全文获取类型
收费全文 | 50345篇 |
免费 | 4225篇 |
国内免费 | 1891篇 |
专业分类
耳鼻咽喉 | 695篇 |
儿科学 | 824篇 |
妇产科学 | 1142篇 |
基础医学 | 6028篇 |
口腔科学 | 910篇 |
临床医学 | 5620篇 |
内科学 | 9059篇 |
皮肤病学 | 1002篇 |
神经病学 | 3447篇 |
特种医学 | 1809篇 |
外国民族医学 | 17篇 |
外科学 | 5963篇 |
综合类 | 4433篇 |
现状与发展 | 5篇 |
一般理论 | 35篇 |
预防医学 | 3541篇 |
眼科学 | 1294篇 |
药学 | 4793篇 |
22篇 | |
中国医学 | 1674篇 |
肿瘤学 | 4148篇 |
出版年
2024年 | 71篇 |
2023年 | 550篇 |
2022年 | 886篇 |
2021年 | 2133篇 |
2020年 | 1408篇 |
2019年 | 1616篇 |
2018年 | 1820篇 |
2017年 | 1485篇 |
2016年 | 1448篇 |
2015年 | 2042篇 |
2014年 | 2569篇 |
2013年 | 2689篇 |
2012年 | 3958篇 |
2011年 | 4066篇 |
2010年 | 2474篇 |
2009年 | 1973篇 |
2008年 | 2921篇 |
2007年 | 2842篇 |
2006年 | 2815篇 |
2005年 | 2782篇 |
2004年 | 2146篇 |
2003年 | 2011篇 |
2002年 | 1761篇 |
2001年 | 1021篇 |
2000年 | 897篇 |
1999年 | 851篇 |
1998年 | 583篇 |
1997年 | 508篇 |
1996年 | 421篇 |
1995年 | 381篇 |
1994年 | 334篇 |
1993年 | 249篇 |
1992年 | 384篇 |
1991年 | 328篇 |
1990年 | 263篇 |
1989年 | 215篇 |
1988年 | 227篇 |
1987年 | 185篇 |
1986年 | 148篇 |
1985年 | 138篇 |
1984年 | 118篇 |
1983年 | 73篇 |
1982年 | 51篇 |
1981年 | 67篇 |
1980年 | 53篇 |
1979年 | 43篇 |
1978年 | 41篇 |
1977年 | 32篇 |
1976年 | 33篇 |
1975年 | 29篇 |
排序方式: 共有10000条查询结果,搜索用时 187 毫秒
41.
Amy Y. Zhang Christopher Burant Alex Z. Fu Gerald Strauss Donald R. Bodner Lee Ponsky 《Journal of psychosocial oncology》2020,38(2):210-227
AbstractPurpose: We examined underlying psychosocial processes of a behavioral treatment for urinary incontinence (UI) of prostate cancer survivors.Design: Secondary analysis of data collected from a clinical trial.Sample: Two hundred forty-four prostate cancer survivors who participated in a clinical trial of behavioral intervention to UI as intervention or control subjects.Methods: The participants had a 3-month behavioral intervention or usual care and were followed up for an additional 3?months. They were assessed at baseline, 3, and 6?months. Latent growth curve models were performed to examine trajectories of each study variable and relationships among the variables.Findings: Increasing self-efficacy and social support were significantly and independently associated with more reduction of urinary leakage frequency over time.Implications for psychosocial oncology: Providing problem-solving skills and social support, including peer support, are essential for empowering patients to reduce UI. 相似文献
42.
43.
44.
Clinical decisions are often made with incomplete information, yet patient care decisions are made every day. Patients vary clinically, uncertainty exists in diagnostic and prognostic information, and many preventive and treatment alternatives have not been formally assessed for their effectiveness. Because scientific information will never answer all clinical questions, clinical decisions are partially based on probabilistic information.
This paper describes how to apply clinical decision making to diagnosing and managing dental caries and periodontal diseases. By using explicit information to quantify probabilities and outcomes, clinical decision making analyzes decisions made under uncertain conditions and the uncertain impact of clinical information.
Clinical decision making incorporates concepts for preventing, diagnosing and treating dental caries and periodontal diseases: risk assessment, evidence-based dentistry, and multiple oral health outcomes. This information can serve as a tool for clinicians to augment clinical judgment and expertise. 相似文献
This paper describes how to apply clinical decision making to diagnosing and managing dental caries and periodontal diseases. By using explicit information to quantify probabilities and outcomes, clinical decision making analyzes decisions made under uncertain conditions and the uncertain impact of clinical information.
Clinical decision making incorporates concepts for preventing, diagnosing and treating dental caries and periodontal diseases: risk assessment, evidence-based dentistry, and multiple oral health outcomes. This information can serve as a tool for clinicians to augment clinical judgment and expertise. 相似文献
45.
目的 探讨Lugol液染色对食管早期癌和癌前病变的诊断价值。方法 对45例食管黏膜可疑病变经内镜以2%Lugol液喷洒染色,观察黏膜染色情况,并取活检送病理组织学检查。结果 45例食管病变染色后,39例呈浅染色或不染色,其中食管癌8例(食管早期癌5例,进展期癌3例),Barrett食管5例,轻至中度不典型增生1l例。本组Lugol液染色对食管早期癌和癌前病变的检出率达46.7%。结论 内镜下应用Lugol液染色结合活检有助于食管早期癌和癌前病变的诊断,且操作简便,具有重要的临床价值。 相似文献
46.
47.
Willemijn A K M Windt Atsua Tahara Alex C A Kluppel Dick de Zeeuw Robert H Henning Richard P E van Dokkum 《Journal of the renin-angiotensin-aldosterone system》2006,7(4):217-224
INTRODUCTION: Vasopressin, mainly through the V1a-receptor, is thought to be a major player in the maintenance of hyperfiltration. Its inhibition could therefore lead to a decrease in progression of chronic renal failure. To this end, the effect of the vasopressin V1a-receptor-selective antagonist, YM218, was studied on proteinuria and focal glomerulosclerosis in early and late intervention after 5/6 nephrectomy in rats, and compared with an angiotensin-converting enzyme inhibitor (ACE-I). MATERIALS AND METHODS: After 5/6 nephrectomy, early intervention was performed between week 2 and 10 thereafter with the V1a-receptor-selective antagonist (VRA, 10 mg/kg/day, n=10), enalapril (ACE-I, 10 mg/kg/day, n=9), or vehicle (n=8). Late intervention was performed in another group between week 6 and 12 with VRA (10 mg/kg/day, n=7), lisinopril (ACE-I, 5 mg/kg/day, n=7), or vehicle (n=7). RESULTS: In early intervention, proteinuria and focal glomerulosclerosis were significantly decreased by VRA compared to vehicle (44+7% and 59+8% respectively). ACE-I significantly decreased proteinuria (67+7%) and a trend towards a decrease in focal glomerulosclerosis was observed (30+18%). In late intervention, VRA did not decrease proteinuria and focal glomerulosclerosis compared to vehicle (21+20% and 0%, respectively), ACE-I significantly lowered proteinuria (92+2%) and a focal glomerulosclerosis (69+1%) lowering trend was observed. CONCLUSION: These results indicate that VRA may protect against early progression of renal injury after 5/6 nephrectomy, whereas its effectiveness seems limited in established renal damage. 相似文献
48.
循证护理在临床实习教学中的尝试 总被引:4,自引:0,他引:4
循证护理(evidence based nursing,EBN),直译为“以证据为基础的护理”,指护理人员在护理实践中将科研结论与病人需求相结合,考虑当时护理环境,结合个人经验,最终做出护理决策,其核心内容是运用现有最好的科学证据为服务对象提供服务。循证护理是20世纪90年代随着循证医学的发展而发展起来的,是一种新概念,新观点,新思维。经调整发现我市实习护生对循证护理了解甚少。 相似文献
49.
Thomas J. Cahill Shehan Hettiaratchy Alex Clarke Peter E.M. Butler 《Transplantation reviews (Orlando, Fla.)》2006,20(2):76-81
Animal models have traditionally provided the basis for preliminary investigation of new techniques prior to trials taking place in human subjects. The timing of when to proceed with human trials is difficult, as the accuracy of preclinical models can only be determined with hindsight. This review outlines the progression from transplantation in animal models to man. Now that many transplant procedures are well established, it is possible to assess the predictive value and limitations of animal models. These results are of great importance in the current debate about composite tissue allotransplantation (CTA) and in particular facial transplantation. This progression of CTA from animal models to man is outlined and compared with early renal, cardiac, and liver transplants. There is some evidence to suggest that animal models may have been misleading in CTA and that this has effectively delayed the transition to humans. The role for animal models in facial transplantation, which is currently making the step to clinical trials, is discussed. 相似文献
50.
目的 :探讨移动数字成像系统GE OECSeries 980 0进行经皮冠状动脉腔内成形术 (PTCA)的可行性和安全性。方法 :回顾分析 32例应用GE OECSeries 980 0X线机进行PTCA治疗冠心病的临床资料。结果 :①本组病例成功率为 90 6 % (2 9/ 32 ) ,血管成功率为 88 1% (37/ 4 2 ) ,病变成功率 83% (39/ 4 7)。成功病例狭窄由术前目测平均直径狭窄(92 8± 3 5 ) %减少到术后的 (6 5± 4 2 ) %。②AMI溶栓后补救性PTCA成功率高。结论 :应用GE OECSeries 980 0X线机能够满足心血管病区心脏介入治疗的需要 ,是安全可行的和具有良好的成本 效益比 相似文献