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51.
Elizabeth Reed Balaiah Donta Anindita Dasgupta Mohan Ghule Madhusudana Battala Saritha Nair Jay G. Silverman Arun Jadhav Prajakta Palaye Niranjan Saggurti Anita Raj 《Public health reports (Washington, D.C. : 1974)》2015,130(6):664-671
Objective
Evidence has linked economic hardship with increased intimate partner violence (IPV) perpetration among males. However, less is known about how economic debt or gender norms related to men''s roles in relationships or the household, which often underlie IPV perpetration, intersect in or may explain these associations. We assessed the intersection of economic debt, attitudes toward gender norms, and IPV perpetration among married men in India.Methods
Data were from the evaluation of a family planning intervention among young married couples (n=1,081) in rural Maharashtra, India. Crude and adjusted logistic regression models for dichotomous outcome variables and linear regression models for continuous outcomes were used to examine debt in relation to husbands'' attitudes toward gender-based norms (i.e., beliefs supporting IPV and beliefs regarding male dominance in relationships and the household), as well as sexual and physical IPV perpetration.Results
Twenty percent of husbands reported debt. In adjusted linear regression models, debt was associated with husbands'' attitudes supportive of IPV (b=0.015, p=0.004) and norms supporting male dominance in relationships and the household (b=0.006, p=0.003). In logistic regression models adjusted for relevant demographics, debt was associated with perpetration of physical IPV (adjusted odds ratio [AOR] = 1.4, 95% confidence interval [CI] 1.1, 1.9) and sexual IPV (AOR=1.6, 95% CI 1.1, 2.1) from husbands. These findings related to debt and relation to IPV were slightly attenuated when further adjusted for men''s attitudes toward gender norms.Conclusion
Findings suggest the need for combined gender equity and economic promotion interventions to address high levels of debt and related IPV reported among married couples in rural India.Intimate partner violence (IPV) perpetrated by male partners or husbands occurs in high proportions globally as well as in low- to middle-income countries such as India.1,2 One recent multi-country household study found that 37% of men in India reported having ever perpetrated physical violence against a female intimate partner in their lifetime. The health burden of IPV has been well demonstrated, with significant effects on women''s sexual and reproductive health (e.g., increased sexually transmitted infections, unintended pregnancy, and poor pregnancy outcomes),3–5 mental health (e.g., anxiety, depression, and substance use),6,7 as well as a multitude of other poor health outcomes among women and their children (e.g., maternal and child malnutrition and infant death).8,9Recent research among women has identified economic hardship (e.g., financial dependence on male partners and economic instability) as increasing women''s vulnerability to IPV.10,11 Although studies have found an association between economic stressors and reports of male IPV perpetration,12–16 no research has examined debt in relation to these outcomes.Debt and other economic decisions in the context of marriage, particularly in rural India, are largely under the control of husbands. Taking on debt may be associated with economic hardship, heightening stress levels among men, and, in turn, IPV. Also, previous work documenting the association between economic hardship and increased IPV perpetration by males12–15 has largely been explained by perceptions related to men''s roles financially within the family (e.g., men who do not feel that they are providing financially for their families may perceive that they are not fulfilling their roles as husbands/males, and this perception related to lack of role fulfillment may escalate into violence). Given that a decision to take on debt appears to be largely controlled by men in this context and likely tied to their perceived role of providing financially for the family, a man''s decision to take out loans may be determined, in part, by their support of masculine gender norms (e.g., a man''s role in the family and male dominance and control in the household). In addition, given previous work highlighting the association between masculine gender norms and a number of risk behaviors among boys and men (e.g., substance and tobacco use and behaviors resulting in unintentional injury),17–21 such gender norms may also be linked to taking on risks associated with debt, as well as debt-acquiring behaviors (e.g., spending money on nonessential goods such as alcohol).Gender norms pertaining to IPV, relationships, and the household are also important driving factors in terms of understanding men''s behaviors related to IPV. Cross-cultural research has shown that societies with greater gender inequities in social norms and policies have a higher prevalence of IPV.21 In the context of India and elsewhere, women''s low status in families and high levels of societal tolerance and acceptance of IPV promote IPV.22More research is needed to understand economic hardship, and debt specifically, in relation to attitudes toward gender norms and IPV perpetration. Many studies have hypothesized that stress related to economic hardship and debts increases IPV perpetration;12–15 however, less research has sought to understand the role of attitudes supportive of men''s more traditional gender norms in relationships or households in contributing to decisions to take on debt as well as in terms of explaining its association with increased IPV perpetration. Increased understanding of the mechanisms that explain associations between economic hardship/debt and IPV is needed to inform prevention approaches, particularly given the increasing number of economic promotion interventions being implemented globally and throughout India.Thus, the primary objective of the current study was to assess household debt in relation to husbands'' support of gender-inequitable norms and norms promoting IPV as well as husbands'' use of IPV against wives. The secondary objective of this study was to assess whether or not gender-based attitudes are important factors in debt and IPV, as well as in explaining an association between debt and increased risk for IPV perpetration among husbands. 相似文献52.
Sushma Tejwani Shoruba Dinakaran Anuja Joshi Rohit Shetty Abhijit Sinha Roy 《Indian journal of ophthalmology》2015,63(11):815-820
Objective:
To study the correlation and effect of sequential measurement of intraocular pressure (IOP) with Goldmann applanation tonometer (GAT), ocular response analyzer (ORA), dynamic contour tonometer (DCT), and Corvis ST.Setting and Design:
Observational cross-sectional series from the comprehensive clinic of a tertiary eye care center seen during December 2012.Methods:
One hundred and twenty-five study eyes of 125 patients with normal IOP and biomechanical properties underwent IOP measurement on GAT, DCT, ORA, and Corvis ST; in four different sequences. Patients with high refractive errors, recent surgeries, glaucoma, and corneal disorders were excluded so as to rule out patients with evident altered corneal biomechanics.Statistical Analysis:
Linear regression and Bland–Altman using MedCalc software.Results:
Multivariate analysis of variance with repeated measures showed no influence of sequence of device use on IOP (P = 0.85). Linear regression r2 between GAT and Corvis ST, Corvis ST and Goldmann-correlated IOP (IOPg), and DCT and Corvis ST were 0.37 (P = 0.675), 0.63 (P = 0.607), and 0.19 (P = 0.708), respectively. The Bland–Altman agreement of Corvis ST with GAT, corneal compensated IOP, and IOPg was 2 mmHg (−5.0 to + 10.3), −0.5 mmHg (−8.1 to 7.1), and 0.5 mmHg (−6.2 to 7.1), respectively. Intraclass correlation coefficient for repeatability ranged from 0.81 to 0.96.Conclusions:
Correlation between Corvis ST and ORA was found to be good and not so with GAT. However, agreement between the devices was statistically insignificant, and no influence of sequence was observed. 相似文献53.
Sharoda Dasgupta Michael R Kramer Eli S Rosenberg Travis H Sanchez Landon Reed Patrick S Sullivan 《JMIR Public Health and Surveillance》2015,1(2)
Background
Travel-related barriers to human immunodeficiency virus (HIV) care, such as commute time and mode of transportation, have been reported in the United States.Objective
The objective of the study was to investigate the association between public transportation use and HIV care attendance among a convenience sample of Atlanta-based, HIV-positive men who have sex with men (MSM), evaluate differences across regions of residence, and estimate the relationship between travel distance and time by mode of transportation taken to attend appointments.Methods
We used Poisson regression to estimate the association between use of public transportation to attend HIV-related medical visits and frequency of care attendance over the previous 12 months. The relationship between travel distance and commute time was estimated using linear regression. Kriging was used to interpolate commute time to visually examine geographic differences in commuting patterns in relation to access to public transportation and population-based estimates of household vehicle ownership.Results
Using public transportation was associated with lower rates of HIV care attendance compared to using private transportation, but only in south Atlanta (south: aRR: 0.75, 95% CI 0.56, 1.0, north: aRR: 0.90, 95% CI 0.71, 1.1). Participants living in south Atlanta were more likely to have longer commute times associated with attending HIV visits, have greater access to public transportation, and may live in areas with low vehicle ownership. A majority of attended HIV providers were located in north and central Atlanta, despite there being participants living all across the city. Estimated commute times per mile traveled were three times as high among public transit users compared to private transportation users.Conclusions
Improving local public transit and implementing use of mobile clinics could help address travel-related barriers to HIV care. 相似文献54.
Meenakshi Singh Abhijit Hazra Yogesh P. Bharitkar Ritu Kalia Ashutosh Sahoo Sneha Saha V. Ravichandiran Shekhar Ghosh Nirup B. Mondal 《RSC advances》2018,8(34):18938
Curcumin has been transformed to several diversely substituted bis-pyrrolizidino/thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via a sequential azomethine ylide cycloaddition reaction using isatins/acenaphthoquinone and proline/thioproline as the reagents. The products were separated via extensive chromatography and characterized by 1D/2D NMR and HRMS analysis.Curcumin has been transformed to several diversely substituted bis-pyrrolizidino/thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via a sequential azomethine ylide cycloaddition reaction. 相似文献
55.
56.
57.
Bhattacharyya S Ghosh S Dasgupta B Mazumder D Roy S Majumdar S 《The Journal of infectious diseases》2002,185(12):1704-1708
This study explored the role of the proinflammatory chemokines macrophage inflammatory protein (MIP)-1alpha and macrophage chemoattractant protein (MCP)-1 for development of antileishmanial activity. There was substantial inhibition in nitrite generation in Leishmania donovani-infected macrophages. A marked elevation of nitrite generation and induction of inducible nitric oxide (NO) synthase (iNOS) mRNA was found in chemokine-primed parasite-infected macrophages. Tumor necrosis factor-alpha, which is the priming signal for NO production, was also up-regulated under similar experimental conditions. The priming with chemokine inhibited the multiplication of L. donovani amastigotes within the intramacrophageal milieu. The antileishmanial effect of chemokines was almost completely abrogated when the macrophages were preincubated with l-N-monomethyl arginine, the specific inhibitor of iNOS. The results of this investigation suggest that the CC chemokines MIP-1alpha and MCP-1 orchestrate an antileishmanial armamentarium via the induction of an NO-mediated regulatory mechanism to control the intracellular growth and multiplication of the Leishmania protozoan. 相似文献
58.
Cardiovascular disease is common, affecting an increasing number of persons as the population ages. To combat this growing health problem, physicians use a multitude of medications in the treatment of their patients. Although pharmacologic therapy greatly enhances quality of life for a majority of patients, there is always the potential for an unfavorable reaction. For example, cardiovascular drugs can induce a vast array of adverse dermatologic responses. This article reviews the various cutaneous reaction patterns that can occur as a result of treatment with vasodilators and other antihypertensive drugs, anticoagulants and antiplatelet drugs, thrombolytic agents, and lipid-lowering agents. 相似文献
59.
Makkuni D Bharadwaj A Wolfe K Payne S Hutchings A Dasgupta B 《Rheumatology (Oxford, England)》2008,47(4):488-490
Objective. The ischaemic complications of giant cell arteritis(GCA) such as blindness and stroke may result from luminal narrowingof the affected arteries. This study focuses on the associationbetween the severity of intimal proliferation on temporal arterybiopsy (TAB) histology and neuro-ophthalmic complications (NOCs)of GCA. Method. We identified 30 cases of biopsy-proven temporal arteritis.One histopathologist (blinded to the clinical details) evaluatedthe TAB specimens and categorized the degree of maximum stenosisdue to intimal hyperplasia into four grades: grade 1 is <50%luminal occlusion due to intimal hyperplasia, grade 2 is 50–75%,grade 3 is >75% and grade 4 is complete luminal occlusion.A second histopathologist (also blinded to the clinical details)independently evaluated the TAB specimens using the same gradingsystem. The NOCs in these patients were noted after a case recordreview. Results. Of the 30 patients, 12 had NOC-10 with eye complications(complete visual loss, anterior ischaemic neuropathy, visualfield defects), one patient had cerebral infarcts and one hadboth cerebral infarcts and vision loss. There was evidence fora statistically significant trend of NOC associated with higherintimal hyperplasia scores (P = 0.001). The scores of the histopathologistsagreed for 23 (77%) patients and differed by 1 category forthe remaining 7 (-statistic 0.88). Conclusions. Our study suggests that the degree of intimal hyperplasiaon TAB histology (routinely available to all hospital units)seems to be closely associated with NOCs of GCA. The study highlightsthe possible prognostic as well as diagnostic role of the biopsy.We feel that intimal hyperplasia noted in biopsy specimens mayhelp us in the risk stratification of GCA patients and targetingof appropriate and novel therapies. KEY WORDS: Intimal hyperplasia, Giant cell arteritis, Neuro-ophthalmic complications
Submitted 1 June 2007; revised version accepted 7 January 2008. 相似文献
60.
Abhijit Chandra Vishal Gupta Manoj Kumar Anit Parihar Ashok Kumar Ramendra Jauhari Devendra Singh P. K. Shrivastav Pankaj Kumar 《Surgical and radiologic anatomy : SRA》2013,35(1):67-74