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Ignacio Mejía‐Calvo Leonardo E. Lpez‐Jurez Said Vzquez‐Leyva Carlos A. Lpez‐Morales Daniel Montoya‐Escutia Pamela G. Merlos Rivera Jos Enrique Herbert‐Pucheta Luis Gerardo Zepeda‐Vallejo Marco Velasco‐Velzquez Lenin Pavn Sonia M. Prez‐Tapia Emilio Medina‐Rivero 《Journal of Cosmetic Dermatology》2021,20(1):150-158
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Potential case of gynecomastia in mummified remains of an early modern period northern finnish vicar
Tiina Väre Francesco M. Galassi Jaakko Niinimäki Juho‐Antti Junno 《Clinical anatomy (New York, N.Y.)》2018,31(5):641-644
We report possibly the oldest evidence of gynecomastia in mummified human remains. Computed tomography was performed on the mummified remains of an early 17th century Northern Finnish vicar. The examination of the scans revealed large bilateral subareolar irregular masses resembling female mammary glands. The nearly septuagenarian vicar appears to have had gynecomastia, as it is a common condition in elderly men, and is sometimes associated with obesity. Gynecomastia is the most likely explanation for these findings. Clin. Anat. 31:641–644, 2018. © 2018 Wiley Periodicals, Inc. 相似文献
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Chronological observation of surgically‐treated granuloma faciale implies the necessity of circumspect management for perinasal nodular subset
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Yurie Shimoda‐Komatsu Misaki Kinoshita‐Ise Hiroaki Shimoyamada Manabu Ohyama 《The Journal of dermatology》2018,45(9):1122-1125
Granuloma faciale (GF) is a rare chronic dermatosis with still unknown etiopathology, which usually presents a solitary, asymptomatic, smooth reddish‐brown to violaceous plaques or nodules on the face. Various therapeutic approaches, including topical application of corticosteroid or tacrolimus and removal with laser, cryotherapy and surgery have been attempted; however, the outcome has been inconsistent. Herein, we report a case of perinasal nodular GF who repeatedly underwent surgical excisions after the failure of laser treatment. Despite its nomenclature, GF does not manifest granulomatous tissue and the lesion is histopathologically characterized by dense dermal cell infiltration devoid of granulomatous changes and not distinguished by a clear border, which partially explains the difficulty of complete removal in our case. Review of the published work delineated that GF could be largely divided into two clinical subsets: plaque and nodular types. The plaque type GF could be responsive to topical tacrolimus, an approach preferentially adopted nowadays, while nodular type GF was often resistant to topical therapies and required surgical or laser removal. The latter subset often arose around the nose. For this location, surgical excision with sufficient removal margin is sometimes technically difficult when an aesthetically acceptable outcome is expected, explaining the basis for local recurrence. Postoperative recurrence could be observed after years of disease‐free period. These observations indicated that the need for respective treatment strategies for the management of distinctive GF subsets. Of note, a multidisciplinary approach combining radical resection and additional supportive intervention with long‐term follow up may be required for perinasal and nodular GF. 相似文献
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