基层医院多层螺旋CT冠状动脉检查现状分析

目的评估基层医院多层螺旋CT(MSCT)行冠状动脉检查的准确性。方法收集在基层医院已行MSCT检查,提示冠状动脉狭窄患者90例,再经北京阜外心血管病医院行冠状动脉造影确诊,采用Kappa检验比较2种检查方法结果的一致性。结果 MSCT诊断冠心病的准确率为88.9%。诊断冠状动脉狭窄程度的准确率39.0%,诊断左前降支、左回旋支和右冠状动脉的准确率分别为45.5%、37.5%和33.3%。在诊断心肌肌桥两者无一相符,诊断钙化准确率较高为80.0%。MSCT检查冠状动脉各节段的狭窄与冠状动脉造影一致性差。左主干、左前降支、左回旋支和右冠状动脉的Kappa值均0.75。结论基层医院MSCT诊断冠心病的准确率较高,但在诊断血管狭窄程度上准确率较低。     

放射治疗后致严重冠状动脉病变一例

放射治疗是胸部肿瘤如何杰金氏病、乳腺癌、肺癌等常见的方法之一,但肿瘤放射治疗所致的放射损伤不可忽视,特别是心血管并发症逐渐引起人们的重视.本文报告1例放射治疗后致严重冠状动脉病变的病例.     

近15年间急性心肌梗死患者的性别年龄演变趋势

目的:了解阜外心血管病医院1994年~2008年急性心肌梗死患者性别和年龄演变趋势。方法:回顾1994年~2008年出院诊断为急性心肌梗死的病历,根据时间段、首发和再发病例以及性别分别计算发病平均年龄、高峰发病年龄段和女性患者的比例,并进行统计学分析。结果:1994年至2008年期间,共收住11 859例,首发病例9 737例,再发病例2 122例。每年收治病例数呈上升趋势(P0.001),差异有统计学意义。首发和再发病例中女性患者比例分别为22.0%和20.5%。女性患者比例随时间增加未见显著变化。首发病例中男性平均年龄随年度增加总体呈下降趋势(P0.01),差异有统计学意义。首发病例中女性平均年龄随年度增加未见显著变化。再发病例中男性平均年龄随年度增加总体呈下降趋势(P0.05),差异有统计学意义。再发病例中女性平均年龄随年度增加总体呈上升趋势(P0.05),差异有统计学意义。首发病例中男性高峰发病年龄段2000年~2008年稳定在45~54岁;女性患者高峰发病年龄段1997年~2008年稳定在65~74岁。结论:急性心肌梗死男性患者发病有年轻化趋势,发病患者中女性的比例保持稳定。男性和女性患者高峰发病年龄段基本保持稳定。     

分光光度法检测清洁验证中过氧化氢残留

目的建立清洁验证中过氧化氢残留物限度检查的含量测定方法。方法利用过氧化氢与高锰酸钾在硫酸介质中能够发生定量氧化还原反应,并引起高锰酸钾溶液吸光度值降低的原理(反应方程式如下:2KMnO4+3H2SO4+5H2O2=K2SO4+2MnSO4+5O2↑+8H2O),采用分光光度法,以纯化水作参比在525nm处测定高锰酸钾溶液吸光度值的变化,并根据其变化值与过氧化氢含量成正比的关系,计算过氧化氢的含量。结果过氧化氢检测浓度在0～19.48μg·mL-1范围内线性良好,回归方程为:Y=0.0063X+0.0008,r=0.9989;最低检出限及最低定量限分别为0.162μg·mL-1、0.540μg.mL-1;平均回收率为102.1%,RSD为8.24%(n=6)。结论本法简便、准确、灵敏度高、重现性好,可用于清洁验证中过氧化氢残留的含量测定。     

一种富含黄酮醇的可可快餐对高胆固醇血症人群胆固醇水平的影响

作者通过单盲、随机、双中心临床研究,对麝香草和报春花根水提物制成的液体制剂Bronchicum Elixir S)及麝香草水提物和报春花根酊剂制作的滴剂Bronchicum Tropfen治疗急性支气管炎病人的疗效进行了等效性对比研究。实验用液体制剂每100g含麝香草提取液(1∶3)5g,报春花根提取液(1∶2)2.5g及其他附加成分;实验用滴剂每100g含麝香草提取液(1∶3)40g,报春花根酊剂(1∶5)20g及其他附加成分。将189名患有急性支气管炎、没有进行过其他治疗、发病时间少于48h的病人随机分为2组。1组94人,其中女66名,男28名,服用液体制剂治疗;另1组95人,其中女…     

可变形的、含亚麻籽的眼部疾病治疗装置

WO2006061596-A1这种医疗装置主要用于眼科疾病的治疗,如睑板腺功能障碍(MGD)、睑板腺疾病、睑板腺增生、睑腺炎、睑板腺囊肿、以及与泪膜不稳定有关的MGD、干眼,睑缘炎和睑结膜炎、前眼色素层炎、虹膜睫状体炎、虹膜炎。它还可以在治疗眼周疾病(肿胀、挫伤或碰伤)中,促进或加速药剂的散瞳和睫状肌麻痹作用,也可治疗偏头痛。这种医疗装置可以改变形状,广泛用于病人面部不同部位,并可以反复使用。可变形的、含亚麻籽的眼部疾病治疗装置@高展     

含乌司他丁肺保护液在心肺转流术中的肺保护作用

Objective To evaluate protective effects of hypothermic pulmonary protective solution with uli-nastatin on lung function during cardiopulmouary bypass (CPB) in the patients with congenital heart disease(CHD) and pulmonary hypertenion. Method Fifty-four children,who had CHD of left-to-fight shunts with moderate-se-rious pulmonary hypertension, were enrolled. They had been performed with the radical operation under CPB from September 2005 to December 2006 in the Department of Cardiovascular Surgery, Children' s Hospital of Zhejiang University. Moderate-serious pulmonary hypertension was defined as pulmonary-to-systolic pressure ratio > 0.45(Pp/Ps > 0.45). Fifty-four children were randomly divided into three groups. Patients in group A (n = 18)didn't receive pulmonary protective solution, and scrved as control; patients in group B (n = 18) were adminis-tered with pulmonary protective solution without ulinastatin;patients in group C (n = 18) were administered with pulmonary protective solution with ulinastatin. The serum concentrations of MDA and MPO were measured at five different time points:pre-operation, 0 h, 3 h, 6 h and 24 h in the intensive care unit (ICU) (T1～5). Patients'lung functions were monitored at T1 - T4. The time of mechanical ventilation was recorded. Results No one died in this study. The mean time of mechanical ventilation was shorter in the group B and group C than that in the group A. The MDA and MPO levels were lower in group B compared with group A at T4. The MDA level at T3-T5 and the MPO level at T4 was lower in group C than those in group A. There were no significant in MDA and MPO levels between group B and group C at five time point.A-aDO2 was lower in groups B and C than those in group A at T3 and T4, whereas at T4, A-aDO2 was lower in group C than that in group B. Cdyn was higher in group B at T3and group C at T3 - T4 than those in group A. Cdyn was lower in groups C than that in group B at T4.Condusions Lung perfusion with hypothermic protective solution during CPB can all lung injury and promote recovery after operation, especialy with ulinastatin.     

含乌司他丁肺保护液在心肺转流术中的肺保护作用

Objective To evaluate protective effects of hypothermic pulmonary protective solution with uli-nastatin on lung function during cardiopulmouary bypass (CPB) in the patients with congenital heart disease(CHD) and pulmonary hypertenion. Method Fifty-four children,who had CHD of left-to-fight shunts with moderate-se-rious pulmonary hypertension, were enrolled. They had been performed with the radical operation under CPB from September 2005 to December 2006 in the Department of Cardiovascular Surgery, Children' s Hospital of Zhejiang University. Moderate-serious pulmonary hypertension was defined as pulmonary-to-systolic pressure ratio > 0.45(Pp/Ps > 0.45). Fifty-four children were randomly divided into three groups. Patients in group A (n = 18)didn't receive pulmonary protective solution, and scrved as control; patients in group B (n = 18) were adminis-tered with pulmonary protective solution without ulinastatin;patients in group C (n = 18) were administered with pulmonary protective solution with ulinastatin. The serum concentrations of MDA and MPO were measured at five different time points:pre-operation, 0 h, 3 h, 6 h and 24 h in the intensive care unit (ICU) (T1～5). Patients'lung functions were monitored at T1 - T4. The time of mechanical ventilation was recorded. Results No one died in this study. The mean time of mechanical ventilation was shorter in the group B and group C than that in the group A. The MDA and MPO levels were lower in group B compared with group A at T4. The MDA level at T3-T5 and the MPO level at T4 was lower in group C than those in group A. There were no significant in MDA and MPO levels between group B and group C at five time point.A-aDO2 was lower in groups B and C than those in group A at T3 and T4, whereas at T4, A-aDO2 was lower in group C than that in group B. Cdyn was higher in group B at T3and group C at T3 - T4 than those in group A. Cdyn was lower in groups C than that in group B at T4.Condusions Lung perfusion with hypothermic protective solution during CPB can all lung injury and promote recovery after operation, especialy with ulinastatin.     

脑出血并发肺部感染152例临床分析

肺部感染是脑出血常见的严重并发症，是脑出血急性期的主要死亡原因之一。我院自1994年1月～2001年12月之间收治的脑出血病人836例，其中并发肺部感染(肺炎组)152例(占18．2％)，无肺部感染(对照组)684例，本就其发生率、易感因素及预后等问题进行探讨。     

某部抓好分散点部队健康教育工作的几点做法

目的 抓好分散部队健康宣传教育,增强官兵自我保健能力,提高部队战斗力。方法 结合部队实际,回顾3年来工作实践,分析具体措施的成效,总结抓好健康教育的做法。结果 总结出抓好分散点部队健康教育工作的3点做法：(1)加大宣传力度,提高思想认识;(2)讲究方式,注重实效;(3)健全制度,抓好落实。采取这些做法,官兵卫生意识及心理素质明显增强,提高了分散点官兵的健康水平,保障了部队的战斗力。结论抓好分散点部队的健康教育是降低部队发病率的的重要手段,是促进部队整体健康水平的有效方法。