浆膜受侵的结直肠癌术后腹腔化疗联合静脉化疗的临床研究

Objective To compare the clinical efficacy of postoperative intraperitoneal chemotherapy combined with systemic chemotherapy to systemic chemotherapy alone for serosa-involved colorectal cancer. Methods According to the criteria of serosa-involving in colorectal cancer, 332 cases were divided into 2 groups prospectively without randomization. Study group (n=166) was treated with intraperitoneal chemotherapy combined with systemic chemotherapy, and control group (n=166) with systemic chemotherapy alone. Incidence of local recurrence, peritoneal metastasis, hepatic metastasis, other distant metastasis and 3-year, 5-year overall survival (OS) rate of two groups were compared. Results 3-year and 5-year OS rates of stage Ⅱ B in study group were similar to those in control group (χ2=0.612,P=0.434). The above rates of stage Ⅲ in study group were higher than those in control group (χ2=3.989,P=0.046). Either the study group or the control group, the 3-year and 5-year OS rates of patients undergone laparoscopic surgery or open surgery were similar (P=0.839, P=0.172). Incidences of local recurrence, peritoneal metastasis and hepatic metastasis in study group were 1.9%, 3.8% and 3.8% respetively, lower than those in control group (8.2%,9.5% and 10.1%,P<0.05). Distant metastasis rate in study group was similar to that in control group. In study group, intraperitoneal chemotherapy regimen with Oxaliplatin had lower rates of peritoneal metastasis and hepatic metastasis as compared to that with Cisplatin (0.9% vs 8.8% ,P=0.019), while the incidences of local recurrence and other distant metastasis were similar. Conclusions Postoperative intraperitoneal chemotherapy combined with systemic chemotherapy improves 3-year and 5-year overall survival rates in patients with stage Ⅲ serosa-involved colorectal cancer, and decreases local recurrence, peritoneal metastasis and liver metastasis rate, especially when intraperitoneal chemotherapy regimen contains Oxaliphtin. Comparing with open surgery, laparoscopic surgery dose not improve 3-year and S-year overall survival rates in patients receiving combined chemotherapy or systemic chemotherapy alone.     

产后失血性休克的相关因素与预防(附17例报告)

目的 探讨产后失血性休克的相关因素和预防措施。方法 对本院2001～2003年收住的17例产后失血性休克患者的临床资料进行回顾性分析。结果 产后失血性休克的相关因素为未作产前检查，有人工流产史，剖宫产以及对产后出血量估计不足。结论 做好产前检查，降低人工流产率和剖宫产率，正确处理3个产程，准确计算产后2h出血量以预防产后失血性休克的发生。     

多功能活动输液架的制作及应用

临床上输液架的功能比较单一，如患者的引流袋无法固定，护理人员只能将引流袋固定在床边，操作起来非常不方便，输液及老年体弱者活动不方便，我科在临床实践中研制了一种多功能活动输液架，经使用，效果甚好，报告如下。     

冲浪者耳

外耳道外生性骨疣(EAE)是常见于在冷水中活动者的外耳道良性病变,故亦名冲浪者耳,过去曾认为病因与遗传、炎症可能有关,现认为与耳部长期受冷水刺激有关。Karegeannes(1995)发现海军潜水员中26％有EAE,Wong等(1999)在307名参加美国西海岸冲浪赛     

原发性纵膈肿瘤的CT诊断价值

原发性纵膈肿瘤是一类较常见的胸部肿瘤，本文收集经手术病理证实且有完整临床及CT与X线资料的58例进行分析，探讨CT检查对该病的诊断价值。     

推拿治疗心脾两虚引起的不寐证

不寐,俗称失眠,是以邪扰神明或心营失养致使经常不易入睡为主症的症证。临床上常见头晕、头痛、心悸、健忘等症状。临床上常以心脾两虚引起的不寐证为常见。笔者推拿治疗本病20例,效果显著,现介绍如下。     

我上演了一场作茧自缚的物质性爱革命

我的物质性爱始于一条红色的T型裤。在商场岁末疯狂打折中，我攥着最后的150元返券，像一只迷路的兔子在眼花缭乱的商品之间乱窜。最后，我做了女性内衣柜台售货小姐的俘虏，她用双手略略撑开那条艳红的T型裤，橘色的灯光穿过透明的蕾丝，细纽的弧形后带勾出令人媚惑的曲线，她说这可以做两个人的新年礼物，难道不是物有所值？     

涎腺肿瘤109例总结和组织病理学研究

本文总结１０９例涎腺肿瘤，其中良性８１例（７４．３１％），恶性２８例（２５．６９％），多形性腺瘤６８例（６２．４％），恶性多形性腺瘤７例（６．４２％）。对良、恶性多形性腺瘤作了组织病理学研究。根据多形性腺瘤各种成分的多少，将其中５６例分成腺瘤型（１８例）、肌上皮型（２０例）和粘液型（１８例）三个亚型。随访４８例有６例复发，其中粘液型５例，腺瘤型１例。随访到１６例的肌上皮型无１例复发。故认为亚型和复     

济南地区儿童IDDM捕获—再捕获方法发病率调查

为了解胰岛素依赖型糖尿病(IDDM)在青少年中的发病情况,我们对济南地区1989～1993年0～14岁儿童的IDDM采用新质控技术捕获一再捕获方法,进行发病率回顾性调查,现报告如下。1 对象与方法 调查对象为济南市五区、章丘市,以及长清、平阴、济阳、商河县15岁以下儿童1207936人。     

SPECT显像在小儿复杂部分性癫痫中的诊断价值：附8例报告

小儿复杂部分性癫痫(Complex Partial Seizures in Children,CPSC)难治性患者需要手术治疗,脑电图(EEG)对脑内深部癫痫病灶难以准确定位。单光子发射计算机断层扫描(SPECF)是80年代后发展成为核医学的主要显像技术,SPECT局部脑