The results of cementless Zweymüller hip system: 5 to 11 years follow-up study

Objective To analyze the intermediate-term results associated with the use of Zweymüller hip system. Methods Review the 116 cases (142 hips) who were treated with total hip replacement from 1996 to 2002 by a single surgeon using cementless Zweymüller hip systems. Results Sixty-one cases (77 hips) were followed up, 50 cases (64 hips) were evaluated both clinically and radiographically while 5 cases (6 hips) and 6 cases (7 hips) were only evaluated clinically and radiographically respectively. The average follow-up period was 7.3 years(range 5 to 11 years). The mean preoperative Harris Hip Score was 46 while the mean postoperative Harris Hip Score was 93. Distal cortical hypertrophy and medullary sclerosis were observed in 30 hips(42.3%) and 33 hips(46.5%) respectively. Heterotopic ossification arose in 45 hips (63.4%). Radiolucent lines occured in 27 stems(38.0%) but in no cups. Radiolucent lines were mosdy observed in Gruen zones 1. Osteolysis occured in 7 cups (9.9%) and 18 stems (25.4%). Osteolysis was mostly observed in Delee Zone 3 and Green zone 7. In the distal Gruen zones 3, 4 and 5, no radiolucent line or osteolysis was observed. No hips had been revised, 3 cups needed revision surgery because of aseptic loosening. Conclusion The 5-11 years follow-up results are satisfactory, but osteolysis is common     

The results of cementless Zweymüller hip system: 5 to 11 years follow-up study

Objective To analyze the intermediate-term results associated with the use of Zweymüller hip system. Methods Review the 116 cases (142 hips) who were treated with total hip replacement from 1996 to 2002 by a single surgeon using cementless Zweymüller hip systems. Results Sixty-one cases (77 hips) were followed up, 50 cases (64 hips) were evaluated both clinically and radiographically while 5 cases (6 hips) and 6 cases (7 hips) were only evaluated clinically and radiographically respectively. The average follow-up period was 7.3 years(range 5 to 11 years). The mean preoperative Harris Hip Score was 46 while the mean postoperative Harris Hip Score was 93. Distal cortical hypertrophy and medullary sclerosis were observed in 30 hips(42.3%) and 33 hips(46.5%) respectively. Heterotopic ossification arose in 45 hips (63.4%). Radiolucent lines occured in 27 stems(38.0%) but in no cups. Radiolucent lines were mosdy observed in Gruen zones 1. Osteolysis occured in 7 cups (9.9%) and 18 stems (25.4%). Osteolysis was mostly observed in Delee Zone 3 and Green zone 7. In the distal Gruen zones 3, 4 and 5, no radiolucent line or osteolysis was observed. No hips had been revised, 3 cups needed revision surgery because of aseptic loosening. Conclusion The 5-11 years follow-up results are satisfactory, but osteolysis is common     

前列腺素E1与甲钻钴胺、丹参治疗DPN疗效观察

DPN患者随机分A组28例，B组30例，C组30例，共2周。结果A组总有效率89．3％，明显高于B组的63．3％及C组的46．7％。结论：三者联合应用可明显改善DPN治疗效果。     

胰岛素强化治疗对早期糖尿病肾病UMA的影响

选取早期DN患者56例，应用胰岛素强化治疗共4周，结果：尿MA水平与TC（r=0．510，P〈0．01）、FPG（r=0、28，P〈0．01）、2hPG（r=0．29，P〈0．01）、HbAl。（r=0．38，P〈0．01）呈正相关。治疗结束时，所有患者血糖和尿MA均达到理想控制，较治疗前明显降低（P〈0．01）。结论：胰岛素强化治疗能够减少UMA。     

体外循环心脏手术后胃肠道并发症的综合治疗探究

目的通过观察体外循环心脏手术后胃肠道并发症的临床特征、危险因素、早期诊断、综合治疗以及预后干预措施,探讨体外循环心脏手术后胃肠道并发症的综合治疗措施。方法回顾我院2002年2月²013年10月收治的56例体外循环心脏手术(心脏瓣膜置换术32例,冠状动脉搭桥14例,心脏瓣膜置换术+冠状动脉搭桥术5例,大血管手术3例,先心病矫治术2例)术后发生胃肠道并发症的患者临床资料,分析胃粘膜保护机制削弱、损伤因素作用增强及机体的神经内分泌功能失调三方面在体外循环心脏术后胃肠道并发症的发生、发展、转归中的作用,总结体外循环心脏手术后胃肠道并发症的综合干预措施。结果 1例原有消化溃疡病史,因大量出血,死于休克;其余55例患者均痊愈出院。对55例患者进行为期12013年10月收治的56例体外循环心脏手术(心脏瓣膜置换术32例,冠状动脉搭桥14例,心脏瓣膜置换术+冠状动脉搭桥术5例,大血管手术3例,先心病矫治术2例)术后发生胃肠道并发症的患者临床资料,分析胃粘膜保护机制削弱、损伤因素作用增强及机体的神经内分泌功能失调三方面在体外循环心脏术后胃肠道并发症的发生、发展、转归中的作用,总结体外循环心脏手术后胃肠道并发症的综合干预措施。结果 1例原有消化溃疡病史,因大量出血,死于休克;其余55例患者均痊愈出院。对55例患者进行为期1⁵年的随访,均无复发和死亡情况。结论体外循环心脏手术后胃肠道并发症病死率高,对术前有胃肠道病史、术前心功能差等高危患者术前可采取必要的预防措施,术后对并发症早期诊断、早期采取综合干预措施,可以提高生率,达到很好的治疗效果。     

曲美他嗪片治疗冠心病并发心力衰竭的临床疗效

目的探讨曲美他嗪片治疗冠心病并发心力衰竭的临床疗效。方法选取咸宁市咸安区妇幼保健院2017年1月—2019年1月收治的冠心病并发心力衰竭患者80例,采取随机数字表法分为对照组与观察组,各40例。对照组予以常规药物治疗,观察组在对照组基础上予以曲美他嗪片治疗,两组均治疗6个月。比较两组临床疗效,治疗前后左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左心室射血分数(LVEF)、24 h出现心肌缺血次数与6分钟步行距离(6MWT)、脑钠肽(BNP)、细胞凋亡抑制因子(Fas/APO-1)、C反应蛋白(CRP)、肿瘤生长因子(TNF-α)。结果观察组治疗总有效率高于对照组(P<0.05)。治疗前两组LVEDD、LVESD、LVEF、24 h出现心肌缺血次数与6MWT比较,差异无统计学意义(P>0.05);治疗后观察组LVEDD、LVESD小于对照组,LVEF高于对照组,24 h出现心肌缺血次数少于对照组,6MWT长于对照组(P<0.05)。治疗前两组BNP、Fas/APO-1、CRP及TNF-α比较,差异无统计学意义(P>0.05);治疗后观察组BNP、Fas/APO-1、CRP及TNF-α低于对照组(P<0.05)。结论曲美他嗪片治疗冠心病并发心力衰竭的临床疗效确切,可有效改善患者心功能,减少炎性反应。     

胸腰段脊柱脊髓损伤减压与固定相关问题探讨(附166例报告)

目的对胸腰段脊柱脊髓、马尾神经损伤患者的外科治疗及几种内固定方法的疗效进行探讨。方法对166例患者的治疗进行回顾分析。该组患者中椎体爆裂性骨折37例,椎体压缩骨折超二分之一109例,椎体骨折脱位14例,多节段或跳跃骨折6例。脊髓损伤按Frankel分级,A级59例、B级46例、C级42例、D级19例。治疗采用后路减压复位122例,前路减压复位、髂骨植骨融合44例。结果术后有123例获3~18个月随访,随防患者中除4例RF钉断裂,5例Harrington上钩脱落,6例棍断裂,其余患者内固定稳固。脊髓、马尾神经恢复:除35例仍为A级外,余脊髓神经功能恢复1~3个级别。结论各种不同内固定可保持或增强脊柱的稳定。胸腰段脊柱脊髓损伤的外科治疗应根据骨折类型、脊髓及马尾神经损伤程度选择手术入路及内固定材料。     

额肌筋膜瓣矫正上睑下垂并发症的统计

目的探讨额肌筋膜瓣悬吊术在矫正上睑下垂术后并发症发生的原因及防治措施,提高手术效果。方法对513例在住院期间及门诊复查中发现的术后并发症进行病因和防治研究。结果发现术后并发症共14种并以相应措施防治。结论绝大部分并发症可以防治,额肌筋膜瓣悬吊术矫治完全性上睑下垂的效果可靠。     

甲基强的松龙与多索茶碱联合治疗AECOPD的疗效

目的探讨甲基强的松龙与多索茶碱联合应用治疗慢性阻塞性肺疾病急性加重期(AECOPD)患者的临床疗效。方法回顾性分析本院2018年7月-2019年3月间收治的70例AECOPD患者的临床资料,所有患者均在常规内科治疗基础上给予甲基强的松龙联合多索茶碱治疗,观察治疗前后患者的动脉血气分析结果及肺功能情况,对临床疗效进行评价。结果患者治疗后Pa CO2水平较治疗前明显下降,而PaO2及SaO2水平较治疗前明显升高(P<0.05),动脉血气分析结果较治疗前有明显改善;患者治疗后肺功能明显改善,FEV1、FEV1/FVC以及PEF水平均优于治疗前(P<0.05),治疗总有效率为94.3%。结论甲基强的松龙联合多索茶碱治疗AECOPD的临床疗效可靠,对于缓解临床症状,改善血气分析结果及肺功能有重要意义。     

类胡萝卜素的新功能与临床评估

类胡萝卜素是一组营养素。广泛存在于许多水果和蔬菜中。过去25年来大量人体试验结果提示,每天摄食500-1000g水果和蔬菜能够预防许多慢性非传染性疾病,而这些水果和蔬菜所含的类胡萝卜素和其他植物营养素起了主要作用。