全文获取类型
收费全文 | 4013篇 |
免费 | 178篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 78篇 |
儿科学 | 34篇 |
妇产科学 | 86篇 |
基础医学 | 738篇 |
口腔科学 | 72篇 |
临床医学 | 336篇 |
内科学 | 887篇 |
皮肤病学 | 70篇 |
神经病学 | 245篇 |
特种医学 | 215篇 |
外科学 | 433篇 |
综合类 | 18篇 |
一般理论 | 4篇 |
预防医学 | 164篇 |
眼科学 | 19篇 |
药学 | 456篇 |
中国医学 | 64篇 |
肿瘤学 | 295篇 |
出版年
2023年 | 21篇 |
2022年 | 65篇 |
2021年 | 136篇 |
2020年 | 71篇 |
2019年 | 83篇 |
2018年 | 105篇 |
2017年 | 71篇 |
2016年 | 119篇 |
2015年 | 186篇 |
2014年 | 199篇 |
2013年 | 234篇 |
2012年 | 372篇 |
2011年 | 346篇 |
2010年 | 211篇 |
2009年 | 177篇 |
2008年 | 243篇 |
2007年 | 261篇 |
2006年 | 230篇 |
2005年 | 218篇 |
2004年 | 145篇 |
2003年 | 135篇 |
2002年 | 94篇 |
2001年 | 100篇 |
2000年 | 70篇 |
1999年 | 71篇 |
1998年 | 29篇 |
1997年 | 15篇 |
1996年 | 28篇 |
1995年 | 15篇 |
1994年 | 10篇 |
1993年 | 9篇 |
1992年 | 23篇 |
1991年 | 11篇 |
1990年 | 7篇 |
1989年 | 7篇 |
1988年 | 5篇 |
1987年 | 5篇 |
1986年 | 9篇 |
1985年 | 9篇 |
1984年 | 10篇 |
1981年 | 3篇 |
1980年 | 3篇 |
1979年 | 3篇 |
1978年 | 8篇 |
1973年 | 4篇 |
1972年 | 4篇 |
1971年 | 6篇 |
1970年 | 4篇 |
1968年 | 4篇 |
1961年 | 2篇 |
排序方式: 共有4214条查询结果,搜索用时 515 毫秒
91.
Comparison of gait before and after superficial trunk muscle exercise and
deep trunk muscle exercise
[Purpose] The purpose of this study was to examine the effects of superficial trunk
muscle and deep trunk muscle exercise on gait. [Subjects] The subjects were 45 young
adults who voluntarily consented to participate. The subjects were divided into a control
group, a superficial muscle exercise group, and a deep muscle exercise group with 15
participants in each group. [Methods] Each group performed the exercises 5 times a week
for 4 weeks. A Gait Analyzer was used to measure the subjects’ gait. A one-way ANOVA was
conducted for analysis between each group. [Results] After 4 weeks, the values from right
heel contact to foot flat, left foot flat to heel off, right foot flat to heel off, and
left heel off to toe off significantly differed among the groups. [Conclusion] The
superficial trunk muscle exercise improved stability, such as the period of mid stance
during gait. The deep trunk muscle exercise improved mobility, such as heel contact to
foot flat and heel off to toe off during gait.Key words: Superficial trunk muscle exercise, Deep trunk muscle exercise, Gait 相似文献
92.
[Purpose] The purpose of this study was to compare shoulder stabilization muscle
activities according to postural changes during flexi-bar exercise. [Subjects] The
subjects included 18 students (10 males, 8 females) at B University. [Methods] The
subjects performed the following flexi-bar exercises: 1) medio-lateral oscillation with
the 90° shoulder abduction, with the hand in the neutral position; 2) dorso-ventral
oscillation with 90° shoulder flexion, with the hand in the neutral position; 3)
superior-inferior oscillation with 90° shoulder flexion, with the 80° hand pronation.
[Results] The activity of the serratus anterior showed significant differences between
each position; however, activities of the upper trapezius and middle trapezius were not
significantly different. [Conclusion] The results of this study indicate that posture
control is important for selective strengthening of the serratus anterior muscle during
flexi-bar exercises.Key words: Flexi-bar exercise, Shoulder stabilization, Muscle activity 相似文献
93.
Bin Li Yang Yang Alper Toker Bentong Yu Chang Hyun Kang Ghulam Abbas Harmik J. Soukiasian Hecheng Li Hiroyuki Daiko Hongjing Jiang Jianhua Fu Jun Yi Kemp Kernstine Marcello Migliore Michael Bouvet Sara Ricciardi Yin-Kai Chao Yong-Hee Kim Yun Wang Zhentao Yu Abbas E. Abbas Inderpal S. Sarkaria Zhigang Li Cooperative Group of International Expert Consensus on Robot-assisted Esophagectomy for Esophageal Cancer 《Journal of thoracic disease》2020,12(12):7387
94.
Mi Na Kim Hyun Ki Kim Choong Nam Shim Hyun Jik Lee Hyuk Lee Jun Chul Park Sung Kwan Shin Sang Kil Lee Yong Chan Lee 《Digestive and liver disease》2014,46(10):898-902
Background
Endoscopic submucosal dissection is applied in selected cases of signet ring cell early gastric cancer. However, factors related to curability of signet ring cell early gastric cancer with this method have not been fully evaluated. Our aim was to evaluate factors related to incomplete resection in signet ring cell early gastric cancer with endoscopic submucosal dissection.Methods
A retrospective analysis was performed on a total of 126 consecutive patients with signet ring cell early gastric cancer who had undergone endoscopic submucosal dissection at the Severance Hospital in Korea, between March 2007 and March 2012. The clinical outcomes were reviewed and factors related to incomplete resection were analysed.Results
Multivariate analysis showed that large tumour size was the only significant factor related to incomplete resection (P = 0.006; hazard ratio, 1.040; 95% confidence interval, 1.101–1.084). In addition, large tumour size was the only significant factor related to endoscopic size underestimation (P < 0.001; hazard ratio, 1.391; 95% confidence interval, 1.221–1.586). The rate of endoscopic size underestimation was significantly higher in tumours with a size ≥20 mm (P < 0.001).Conclusions
To improve the curability of signet ring cell early gastric cancer with endoscopic submucosal dissection, larger tumours (especially tumour with a size ≥20 mm) should be resected with a larger margin. 相似文献95.
Jong Min Lee Ji Young Jang Seung Hwan Lee Hongjin Shim Jae Gil Lee 《Yonsei medical journal》2014,55(6):1606-1610
Purpose
The aim of this study was to evaluate the feasibility of short hospital stays after laparoscopic appendectomy for uncomplicated appendicitis.Materials and Methods
The records of 142 patients who underwent laparoscopic appendectomy for uncomplicated appendicitis from January 2010 to December 2012 were analyzed retrospectively. Patients were allocated to an early (<48 hours) or a late (>48 hours) group by postoperative hospital stay. Postoperative complications and readmission rates in the two groups were evaluated and compared.Results
Overall mean patient age was 50.1 (±16.0) years, and mean hospital stay was 3.8 (±2.8) days. Fifty-four patients (group E, 38.0%) were discharged within 48 hours of surgery, and 88 patients (group L, 62.0%) stayed more than 48 hours. Overall complication rates were similar in the two groups (14.8% vs. 21.6%, p=0.318), and wound complications (13.0% vs. 12.5%), postoperative bowel obstruction (1.9% vs. 2.3%), and abdominal pain (1.9% vs. 3.4%) were not significantly different.Conclusion
Patients that undergo laparoscopic appendectomy due to uncomplicated appendicitis may be safely discharged within 48 hours. Further study should be conducted to determine the optimal length of hospital stay after laparoscopic appendectomy to reduce hospital costs. 相似文献96.
Sung-Jin Hong Myeong-Ki Hong Young-Guk Ko Donghoon Choi Geu-Ru Hong Jae-Kwang Shim Young-Lan Kwak Sak Lee Byung-Chul Chang Yangsoo Jang 《Yonsei medical journal》2014,55(5):1246-1252
Purpose
We sought to evaluate the clinical usefulness of decision making by a multidisciplinary heart team for identifying potential candidates for transcatheter aortic valve implantation (TAVI) in patients with symptomatic severe aortic stenosis.Materials and Methods
The multidisciplinary team consisted of two interventional cardiologists, two cardiovascular surgeons, one cardiac imaging specialist, and two cardiac anesthesiologists.Results
Out of 60 patients who were screened as potential TAVI candidates, 31 patients were initially recommended as appropriate for TAVI, and 20 of these 31 eventually underwent TAVI. Twenty-two patients underwent surgical aortic valve replacement (AVR), and 17 patients received only medical treatment. Patients who underwent TAVI and medical therapy were older than those who underwent surgical AVR (p<0.001). The logistic Euroscore was significantly highest in the TAVI group and lowest in the surgical AVR group (p=0.012). Most patients in the TAVI group (90%) and the surgical AVR group (91%) had severe cardiac symptoms, but only 47% in the medical therapy group had severe symptoms. The cumulative percentages of survival without re-hospitalization or all-cause death at 6 months for the surgical AVR, TAVI, and medical therapy groups were 84%, 75%, and 28%, respectively (p=0.007, by log-rank).Conclusion
TAVI was recommended in half of the potential candidates following a multidisciplinary team approach and was eventually performed in one-third of these patients. One-third of the patients who were initially considered potential candidates received surgical AVR with favorable clinical outcomes. 相似文献97.
Jong Bum Choi Yon Hee Shim Youn-Woo Lee Jeong Soo Lee Jong-Rim Choi Chul Ho Chang 《Yonsei medical journal》2014,55(5):1430-1435
Purpose
We evaluated the incidence and risk factors of postoperative nausea and vomiting (PONV) in patients with fentanyl-based intravenous patient-controlled analgesia (IV-PCA) and single antiemetic prophylaxis of 5-hydroxytryptamine type 3 (5 HT3)-receptor antagonist after the general anesthesia.Materials and Methods
In this retrospective study, incidence and risk factors for PONV were evaluated with fentanyl IV-PCA during postoperative 48 hours after various surgeries.Results
Four hundred-forty patients (23%) of 1878 had showed PONV. PCA was discontinued temporarily in 268 patients (14%), mostly due to PONV (88% of 268 patients). In multivariate analysis, female, non-smoker, history of motion sickness or PONV, long duration of anesthesia (>180 min), use of desflurane and intraoperative remifentanil infusion were independent risk factors for PONV. If one, two, three, four, five, or six of these risk factors were present, the incidences of PONV were 18%, 19%, 22%, 31%, 42%, or 50%. Laparoscopic surgery and higher dose of fentanyl were not risk factors for PONV.Conclusion
Despite antiemetic prophylaxis with 5 HT3-receptor antagonist, 23% of patients with fentanyl-based IV-PCA after general anesthesia showed PONV. Long duration of anesthesia and use of desflurane were identified as risk factors, in addition to risk factors of Apfel''s score (female, non-smoker, history of motion sickness or PONV). Also, intraoperative remifentanil infusion was risk factor independent of postoperative opioid use. As the incidence of PONV was up to 50% according to the number of risk factors, risk-adapted, multimodal or combination therapy should be applied. 相似文献98.
Hyung Soon Lee Hongjin Shim Ji Young Jang Hosun Lee Jae Gil Lee 《Yonsei medical journal》2014,55(2):395-400
Purpose
This study was undertaken to assess the feasibility of early feeding in patients that have undergone emergency gastrointestinal (GI) surgery.Materials and Methods
The authors retrospectively reviewed 84 patients that underwent emergency bowel resection and/or anastomosis from March 2008 to December 2011. Patients with severe shock, intestinal ischemia, sustained bowel perforation, or short bowel syndrome were excluded. Patients were divided into the early (group E; n=44) or late (group L; n=40) group according to the time of feeding commencement. Early feeding was defined as enteral feeding that started within 48 hours after surgery. Early and late feeding groups were compared with respect to clinical data and surgical outcomes.Results
The most common cause of operation was bowel perforation, and the small bowel was the most commonly involved site. No significant intergroup differences were found for causes, sites, or types of operation. However, length of stay (LOS) in the intensive care unit (1 day vs. 2 days, p=0.038) and LOS in the hospital after surgery were significantly greater (9 days vs. 12 days, p=0.012) in group L than group E; pulmonary complications were also significantly more common (13.6% vs. 47.5%, p=0.001) in group L than group E.Conclusion
After emergency GI surgery, early feeding may be feasible in patients without severe shock or bowel anastomosis instability. 相似文献99.
Background
Small bowel volvulus caused by a jejunal trichobezoar is an extremely rare and life-threatening emergency in children.Case characteristics
An 8-year-old girl with abdominal pain and persistent bilious vomiting.Observation
The abdominal computed tomography scan showed a solitary intraluminal mass and a whirl sign, suggesting the small bowel volvulus. Emergency laparoscopic exploration revealed the rotated segment of small bowel loops by a jejunal trichobezoar.Outcome
Satisfactory recovery after surgery.Message
Trichobezoars should be considered in the differential diagnosis of abdominal pain and projectile vomiting in children. 相似文献100.
In Bum Suh Dae Wui Yoon Won-Oak Oh Eun Joo Lee Kyung Hoon Min Gyu Young Hur Seung Heon Lee Sung Yong Lee Sang Yeub Lee Chol Shin Jae Jeong Shim Kwang Ho In Kyung Ho Kang Je Hyeong Kim 《Journal of Korean medical science》2014,29(4):556-563
This study was performed to examine the role of transglutaminase 2 (TG2) in ventilator-induced lung injury (VILI). C57BL/6 mice were divided into six experimental groups: 1) control group; 2) lipopolysaccharide (LPS) group; 3) lung protective ventilation (LPV) group; 4) VILI group; 5) VILI with cystamine, a TG2 inhibitor, pretreatment (Cyst+VILI) group; and 6) LPV with cystamine pretreatment (Cyst+LPV) group. Acute lung injury (ALI) score, TG2 activity and gene expression, inflammatory cytokines, and nuclear factor-κB (NF-κB) activity were measured. TG2 activity and gene expression were significantly increased in the VILI group (P < 0.05). Cystamine pretreatment significantly decreased TG2 activity and gene expression in the Cyst+VILI group (P < 0.05). Inflammatory cytokines were higher in the VILI group than in the LPS and LPV groups (P < 0.05), and significantly lower in the Cyst+VILI group than the VILI group (P < 0.05). NF-κB activity was increased in the VILI group compared with the LPS and LPV groups (P < 0.05), and significantly decreased in the Cyst+VILI group compared to the VILI group (P = 0.029). The ALI score of the Cyst+VILI group was lower than the VILI group, but the difference was not statistically significant (P = 0.105). These results suggest potential roles of TG2 in the pathogenesis of VILI.