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91.
Ahmed S. Bahaj Haddad H. Alkaff Bashair N. Melebari Anwar N. Melebari Suhail I. Sayed Syeddah S. Mujtaba Sherif K. Abdelmonim Saeed A. Alghamdi Fares E. Alghamdi Omar A. Abu Suliman Mohammad A. Alessa Firas R. Abi Sheffah Anas H. Al-Tammas Rajab A. Al-Zahrani Osama A. Marglani John C. Heaphy Osama A. Bawazir Ameen Z. Alherabi 《Saudi medical journal》2020,41(10):1098
Objectives:To evaluate the accuracy and efficacy of fine-needle aspiration cytology (FNAC) in diagnosing thyroid nodules, correlating it with the histopathological findings.Methods:A retrospective evaluation of 314 patients was undertaken at a tertiary referral center of King Abdullah Medical City (KAMC), Makkah, Kingdom of Saudi Arabia, between 2010-2019. Patients who presented with thyroid swellings underwent ultrasonography and FNAC. If indicated, surgery was performed. The FNAC findings were compared to the final histopathological reports.Results:The findings for FNAC from our data set of 314 patients showed a sensitivity value of 79.8%, specificity of 82.1%, accuracy of 74.8%, positive predictive value of 74.8%, and negative predictive value of 85.9%.Conclusion:Our study showed that FNAC has high sensitivity and specificity in the initial evaluation of patients with thyroid nodules. When guided by ultrasonography, the accuracy can be markedly improved. Molecular markers once widely available can improve the diagnostic power of FNAC to be no less than the histopathologic evaluation of thyroid tissue. 相似文献
92.
Sevil Hemayat Akbar Shafiee Saeed Oraii Farideh Roshanali Farshid Alaedini Amirhossein Sami Aldoboni 《Journal of interventional cardiac electrophysiology》2014,40(1):81-86
Purpose
This study aimed at comparing the development of tricuspid and mitral regurgitation between the right ventricular outflow tract (RVOT) and right ventricular apex (RVA) pacing.Methods
We prospectively enrolled 164 patients for permanent pacemaker implantation due to sick sinus syndrome or atrioventricular block and randomly divided them into two equal groups to receive either RVOT or RVA pacing. Patients with heart failure or valvular disease were excluded. The post-procedural echocardiographic evaluations were performed 1 year after the pre-procedural echocardiography, and the results were compared with respect to the development of mitral and tricuspid regurgitation and probable changes in the ejection fraction (EF).Results
Age, gender, pacing mode, and baseline cardiac rhythm did not significantly differ between the RVOT and RVA pacing groups. The incidence of mitral regurgitation was significantly higher in the RVA group (p?=?0.03), but the incidence of tricuspid regurgitation was similar in both groups. There was a trend toward less tricuspid regurgitation in the RVOT group; however, it was not statistically significant. The mean EF was not significantly different between the study groups.Conclusion
It seems that the incidence of mitral regurgitation in RVA pacing is significantly higher than that in RVOT pacing. The formation of tricuspid regurgitation needs to be discussed in the future.Clinical trial registration number
IRCT201103146061N1 相似文献93.
L. J. Gray M. A. Saeed D. Smith W. Hanif K. Khunti 《Diabetes, obesity & metabolism》2014,16(6):527-536
94.
95.
Haddad H. Alkaff Bayan O. Besharah Deemah H. Bukhari Suhail I. Sayed Mohammad A. Alessa Sherif K. Abdelmonim Saeed A. Alghamdi Fares E. Alghamdi Omar A. Abu Suliman Firas R. Abi Sheffah Anas H. Al-Tammas Rajab A. Al-Zahrani Osama A. Marglani John C. Heaphy Osama A. Bawazir Ameen Z. Alherabi 《Saudi medical journal》2020,41(12):1330
96.
97.
Ahmed Bari Daniel Grenier Jabrane Azelmat Saeed Ali Syed Abdulrahman M. Al‐Obaid Eric C. Hosten 《Chemical biology & drug design》2019,94(4):1750-1759
In continuation with our research program on the development of novel bioactive molecules, we report herein the design and synthesis of a series of diversified heterocycles ( 4 – 22 ). The synthesized compounds were evaluated for their anti‐inflammatory activity. The chemical structures of the newly synthesized compounds have been confirmed by NMR, FTIR, and microanalysis. 相似文献
98.
99.
Svenja Sydor Paul Manka Lea van Buren Sarah Theurer Suzan Schwertheim Jan Best Janette Heegsma Ali Saeed Diana Vetter Martin Schlattjan Anna Dittrich Maria I. Fiel Hideo A. Baba Alexander Dechêne Francisco J. Cubero Guido Gerken Ali Canbay Han Moshage Scott L. Friedman Klaas Nico Faber Lars P. Bechmann 《Liver international》2020,40(9):2172-2181
100.
Finn AV Saeed O Virmani R 《Circulation research》2012,110(9):e64; author reply e65-e64; author reply e66