全文获取类型
收费全文 | 25827篇 |
免费 | 1994篇 |
国内免费 | 101篇 |
专业分类
耳鼻咽喉 | 217篇 |
儿科学 | 600篇 |
妇产科学 | 400篇 |
基础医学 | 3520篇 |
口腔科学 | 329篇 |
临床医学 | 2786篇 |
内科学 | 5796篇 |
皮肤病学 | 314篇 |
神经病学 | 2384篇 |
特种医学 | 836篇 |
外科学 | 4287篇 |
综合类 | 281篇 |
现状与发展 | 1篇 |
一般理论 | 25篇 |
预防医学 | 1888篇 |
眼科学 | 404篇 |
药学 | 1792篇 |
中国医学 | 44篇 |
肿瘤学 | 2018篇 |
出版年
2023年 | 258篇 |
2022年 | 453篇 |
2021年 | 998篇 |
2020年 | 517篇 |
2019年 | 813篇 |
2018年 | 927篇 |
2017年 | 650篇 |
2016年 | 666篇 |
2015年 | 760篇 |
2014年 | 1042篇 |
2013年 | 1313篇 |
2012年 | 2074篇 |
2011年 | 2098篇 |
2010年 | 1122篇 |
2009年 | 980篇 |
2008年 | 1617篇 |
2007年 | 1607篇 |
2006年 | 1470篇 |
2005年 | 1418篇 |
2004年 | 1358篇 |
2003年 | 1258篇 |
2002年 | 1236篇 |
2001年 | 187篇 |
2000年 | 151篇 |
1999年 | 227篇 |
1998年 | 250篇 |
1997年 | 204篇 |
1996年 | 161篇 |
1995年 | 158篇 |
1994年 | 160篇 |
1993年 | 128篇 |
1992年 | 113篇 |
1991年 | 75篇 |
1990年 | 97篇 |
1989年 | 71篇 |
1988年 | 74篇 |
1987年 | 90篇 |
1986年 | 77篇 |
1985年 | 64篇 |
1984年 | 94篇 |
1983年 | 80篇 |
1982年 | 89篇 |
1981年 | 81篇 |
1980年 | 85篇 |
1979年 | 50篇 |
1978年 | 56篇 |
1977年 | 47篇 |
1975年 | 39篇 |
1974年 | 34篇 |
1973年 | 35篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
12.
13.
14.
15.
16.
John P. Sundberg Kathleen A. Silva Victoria E. Kennedy John J. Wilson Nicholas E. Gott Beth A. Sundberg Derry C. Roopenian 《Experimental dermatology》2019,28(9):1091-1093
2‐deoxy D‐glucose (2DG) was tested for efficacy in treating alopecia areata using the C3H/HeJ skin graft model. 2DG has proven to be efficacious in treatment of various mouse models of autoimmunity with minimal serious side effects noted. This agent has been shown to normalize abnormally activated T‐cell populations while also preventing cell surface expression of NKG2D; key factors defining alopecia areata disease progression. Daily oral ingestion of 2DG via drinking water to mice with patchy or diffuse alopecia areata for 16 weeks failed to prevent expansion of alopecia or cause regrowth of hair in treated mice. Histologically, there were no differences between treated and control groups. These results indicate that, while 2DG is effective for some autoimmune diseases, it was not efficacious for the cell‐mediated autoimmune mouse disease, alopecia areata. 相似文献
17.
Dane Scantling Robert Kucejko John Williamson Alvaro Galvez Amanda Teichman Ryan Gruner Nicholas Serniak Brendan McCracken 《Injury》2019,50(1):54-60
Background
Most elderly trauma patients suffer blunt head injury and many utilize antithrombotic (AT) medications. The utility of delayed CT-head (D-CTH) in neurologically intact elderly patients using AT who have an intracranial hemorrhage (ICH) on presentation is unknown. We hypothesized that D-CTH would not alter clinical management and aimed to evaluate the role of D-CTH in this population.Methods
A retrospective cohort study was performed. Patients ≥65 years sustaining blunt head injuries from January 2010 to July 2017 were identified using our level 1 trauma center database. AT-patients presenting with ICH who underwent D-CTH were included. Patients with worsened ICH were compared to those with stable to improved ICH on D-CTH. AT-patients were compared to a cohort of non-AT patients. Fisher’s Exact and Mann-Whitney U tests were utilized and a power analysis conducted.Results
137?A?T and 34 non-AT patients were identified. There was no difference in hemorrhage progression or appearance of new ICH. No patient had a change in management from D-CTH in either cohort. AT-patients were slightly older (p?<?0.001), but cohorts were otherwise similar.50 AT-patients with worsened ICH were compared to 87 with stable ICH. There was no difference in cohort demographics. Hemorrhage progression did not vary with type of AT used but did increase if multiple types of synchronous ICH were present (p?<?0.001).Conclusions
Our data supports abstaining from routine D-CTH of elderly ICH patients with an intact neurologic examination who are utilizing aspirin, clopidogrel or warfarin. Conclusions cannot be drawn regarding new oral anticoagulants (NOACs) given low enrollment. Further multicenter study is required to provide adequate power and detect small levels of management change. 相似文献18.
Nicholas Beazley-Long 《中国神经再生研究》2019,(1)
<正>Microvascular dysfunction and rheumatoid arthritis(RA):Across the UK severe osteoarthritis affects~5–7%and RA affects~1%of the population.These are the most common causes of disabling chronic pain and are major burdens on individuals and society.Consequently,the annual financial cost to the UK economy for arthritis is in the billions of pounds.People living with painful inflammatory conditions and in 相似文献
19.
20.