胰岛素对数种缩血管物质作用的影响

目的 观察胰岛素对去甲肾上腺素、内皮素-１、氯化钾（ＫＣＩ）、血管紧张素Ⅱ和５－羟色胺缩血管作用的影响。方法 用ＳＤ大鼠的离体动脉血管观察缩血管物质的作用。结果 在含有１ｍＵ／ｍｌ胰岛素环境中，胰岛素对数种缩血管作用机制不同的物质有程度不同的血管增敏作用。对去甲肾上腺素、内皮素－１和ＫＣＩ有明显的增敏效果；对血管紧张素Ⅱ有增敏趋势，但无显著性差异；对5－羟色胺无增敏效应。结论 胰岛素在高血压的发病过程中可能起重要作用。     

大肠癌细胞增殖分化与多药耐药性的关系

目的 :探讨大肠癌细胞增殖、分化与肿瘤细胞耐药性之间的关系。方法 :收集大肠癌标本 51例 ,显微镜下观察肿瘤的分化情况 ,并用免疫组织化学ABC法检测肿瘤细胞增殖细胞核抗原 (PCNA)和P 糖蛋白 (P Glycoprotein ,P gp)的表达情况 ,分析肿瘤细胞增殖、分化与Pgp表达的关系。 结果 :不同类型和分化程度的肿瘤细胞PCNA和Pgp的表达不同 ,但是 ,它们相互之间无明显的相关性 (P >0 .0 5)。结论 :大肠癌细胞增殖、分化与耐药性的产生分别为独立的现象     

免疫抑制剂SIIA9268A的研究.Ⅰ.发酵、分离及理化性质

在用含ｒａｐａｍｙｃｉｎ结合蛋白基因（ＲＢＰ）的啤酒酵母ＲＳ１８８Ｎ及其变株ＲＳ１８８Ｎ△ｒｂｐ：：：ＬＥＵ筛选免疫抑制剂的过程中，得到活性菌株Ｎｏ．ＳＩＩＡ９２６８（鉴定为吸水链霉菌东湖变种）。应用硅胶柱层析和制备ＴＬＣ等方法从其发酵液中分离出活性化合物ＳＩＡ９２６８Ａ。经理化性质鉴定与ｒａｐａｍｙｃｉｎ同质。     

Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer

Purpose  

An open-label Phase 1 study of recombinant prime-boost poxviruses targeting CEA and MUC-1 in patients with advanced pancreatic cancer was conducted to determine safety, tolerability and obtain preliminary data on immune response and survival.     

ATP和SNP控制性降压对血流动力学的影响

对比研究三磷酸腺苷（ＡＴＰ）和硝普钠（ＳＮＰ）控制性降压对氯胺酮麻醉犬血流动力学的影响。选择犬１４只，随机分为ＡＴＰ组和ＳＮＰ组，由股静脉持续输入ＡＴＰ和ＳＮＰ使ＭＡＰ降低３０％￣４０％，维持３０ｍｉｎ，分别于降压前、降压后１５ｍｉｎ、３０ｍｉｎ及停止降压后１５ｍｉｎ用Ｓｗａｎ－Ｇａｎｚ漂浮导管测定血流动力学指标。结果表明，ＡＴＰ、ＳＮＰ降压期间ＳＶＲ、ＬＶＳＷ显著降低，ＣＯ、ＰＣＷＰ、ＳＶ、ＲＶ     

蟑螂的化学防制进展

近年来,蟑螂危害日趋严重,由于蟑螂孳生栖息环境特殊,故对其防制有较高的要求,所以根除蟑螂仍是一个艰巨的任务.为了消灭蟑螂,人们在长期防制工作中,积累了不少经验,也找到了一些行之有效的办法.诸如环境治理、清除蟑螂的栖息地、综合防制等.媒介防制方针虽然有了根本的改变,但是并不反对应用杀虫剂,而是要正确地使用,以期更好地发挥化学防制的作用.因此,化学杀虫剂不仅是目前乃至是今后较长时期内防制蟑螂的主要手段.     

Acupuncture Treatment of Frequent Urination

Patient Liu （a male office worker of a company in Beijing）, aged 49, paid his first visit on March 10, 2003, with the chief complaint of frequent urination at night for over one year. One year ago, he started to have frequent urination 4-5 times every night, which disturbed his sleep and made him fatigue during the day. Though he tried to drink less water, the above symptoms couldn＇t be alleviated. The condition was accompanied by such symptoms as listlessness, general lassitude,     

The witches’ brew of spirituality and medicine

Recent proposals to join spirituality and medicine are facile and ill defined. The notion that physicians have the time or training to make assessments and recommendations about spirituality is misguided. Whenever a physician demonstrates personal caring for a patient, the healing process is likely enhanced, and in that sense, physicians often promote the spirituality of the patient. However, recent proposals to extend the physician’s task to that of assessing religion and directing the patient toward approved forms of spirituality are inappropriate. The languages of religion and science are radically different. The cultural body-mind split will not be solved by such simplistic solutions as having physicians endorse spirituality, which will result only in denigration of both medicine and religion. Physicians are encouraged to rely on clinically trained ministers for assistance in understanding the patient’s state of mind or spirit and its possible effects on the course of illness and health.     

颞下颌关节的三维有限元法研究

本研究利用颞下颌关节ＣＴ扫描资料和计算机图像分析处理技术以及三维有限元方法相结合建立了髁状突的三维有限元模型，结果表明，此方法在技术上是可行的并将有助于颞下颌关节的临床和基础研究。