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Ultrasonographic evaluation of gastrointestinal graft‐versus‐host disease after hematopoietic stem cell transplantation
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Mutsumi Nishida Akio Shigematsu Megumi Sato Yusuke Kudo Satomi Omotehara Tatsunori Horie Takahito Iwai Tomoyuki Endo Akihiro Iguchi Hitoshi Shibuya Kanako Hatanaka Chikara Shimizu Takanori Teshima 《Clinical transplantation》2015,29(8):697-704
Gastrointestinal graft‐versus‐host disease (GI‐GVHD) is a major and life‐threatening complication of hematopoietic stem cell transplantation (HSCT). This study evaluated the efficacy of ultrasonography (US) for assessing and monitoring GI‐GVHD. GI tract was evaluated by US in 81 patients. US findings were positive in 43 patients, including 11 false positive, and negative in 38 patients. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of US for the diagnosis of GI‐GVHD were 100%, 78%, 74%, 100%, and 86%, respectively. Diffuse wall thickening of the ileum was the most frequent finding in patients with GI‐GVHD. Severity of GI‐GVHD was correlated with the thickness of internal low echoic layer of the wall, the echogenicity of mesenteric fat tissue, and the intensity of Doppler signaling. We classified US findings of GI‐GVHD into four US grades. There was a significant correlation between clinical stage of GI‐GVHD and the US grade. These ultrasonographic abnormalities were improved with clinical improvement of GI‐GVHD upon treatment. Thus, US is an effective and efficient non‐invasive means of identifying the extent and severity of GI‐GVHD and monitoring response to treatment. 相似文献
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Selenium deficiency in a patient with Crohn's disease receiving long-term total parenteral nutrition
Ishida T Himeno K Torigoe Y Inoue M Wakisaka O Tabuki T Ono H Honda K Mori T Seike M Yoshimatsu H Sakata T 《Internal medicine (Tokyo, Japan)》2003,42(2):154-157
We report a case of selenium deficiency in a patient with Crohn's disease on long-term total parenteral nutrition (TPN). She manifested lassitude of the legs, discoloration of the nail beds, and macrocytosis. Since her plasma selenium level was found to be below the measurable level, we diagnosed this case as selenium deficiency. After intravenous administration of sodium selenite, her symptoms were reversed. Careful attention should be paid to selenium deficiency when a patient receives long-term TPN; supplementary administration of selenium via TPN may be required because selenium is often not routinely added to TPN formulations. 相似文献
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Masatsugu Ohara Goki Suda Megumi Kimura Osamu Maehara Tomoe Shimazaki Taku Shigesawa Kazuharu Suzuki Akihisa Nakamura Naoki Kawagishi Masato Nakai Takuya Sho Mitsuteru Natsuizaka Kenichi Morikawa Koji Ogawa Tomoe Kobayashi Minoru Uebayashi Ryo Takagi Isao Yokota Tsuyoshi Shimamura Naoya Sakamoto 《Hepatology research》2020,50(6):715-725
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An overall characterization of pediatric acute lymphoblastic leukemia with CRLF2 overexpression
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![点击此处可从《Genes, chromosomes & cancer》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Mio Yano Toshihiko Imamura Daisuke Asai Akiko Moriya‐Saito So‐ichi Suenobu Daiichiro Hasegawa Takao Deguchi Yoshiko Hashii Hirohide Kawasaki Hiroki Hori Yoshiyuki Kosaka Koji Kato Keizo Horibe Keiko Yumura‐Yagi Junichi Hara Kenji Matsumoto Nobutaka Kiyokawa Megumi Oda Atsushi Sato for the Japan Association of Childhood Leukemia Study 《Genes, chromosomes & cancer》2014,53(10):815-823
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Ohta Shin Tanaka Akihiko Jinno Megumi Hirai Kuniaki Miyata Yoshito Yamaguchi Munehiro Homma Tetsuya Muramoto Mayumi Watanabe Yoshio Suzuki Shintaro Yokoe Takuya Sagara Hironori 《Sleep & breathing》2020,24(2):523-532
Sleep and Breathing - Obesity increases the severity of asthma, and patients with severe asthma are often complicated with obstructive sleep apnea syndrome (OSAS), a concomitant disease of obesity.... 相似文献
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