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71.
72.
Richard Reading 《Child: care, health and development》2009,35(1):142-142
A systematic review of the features that indicate intentional scalds in children .
Maguire S. , Moynihan S. , Mann M. , Potokar T. & Kemp A. M. ( 2008 ) Burns , 34 , 1072 – 1081 .
DOI: 10.1016/j.burns.2008.02.011 . 相似文献
Maguire S. , Moynihan S. , Mann M. , Potokar T. & Kemp A. M. ( 2008 ) Burns , 34 , 1072 – 1081 .
DOI: 10.1016/j.burns.2008.02.011 . 相似文献
73.
74.
Richard Reading 《Child: care, health and development》2009,35(2):281-281
Long-term effects of organized violence on young Middle Eastern refugees' mental health .
Montgomery E. ( 2008 ) Social Science & Medicine , 67 , 1596 – 1603 .
DOI: 10:1016/j.socscimed.2008.07.020. 相似文献
Montgomery E. ( 2008 ) Social Science & Medicine , 67 , 1596 – 1603 .
DOI: 10:1016/j.socscimed.2008.07.020. 相似文献
75.
Richard Reading 《Child: care, health and development》2009,35(3):432-432
Outcomes of conduct problems in adolescence: 40-year follow-up of national cohort .
Colman I. , Murray J. , Abbott R. A. , Maughan B. , Kuh D. , Croudace T. J. & Jones P. B. ( 2009 ) BMJ , 338 , a2981 .
DOI: 10.1136/bmj.a2981 . 相似文献
Colman I. , Murray J. , Abbott R. A. , Maughan B. , Kuh D. , Croudace T. J. & Jones P. B. ( 2009 ) BMJ , 338 , a2981 .
DOI: 10.1136/bmj.a2981 . 相似文献
76.
Gahan J Pandina Robert Bilder Philip D Harvey Richard S E Keefe Michael G Aman Georges Gharabawi 《Neuropsychopharmacology》2007,62(3):226-234
BACKGROUND: Effects of risperidone on cognitive function in children with disruptive behavior disorders (DBDs) and subaverage intelligence quotient (IQ) were assessed. METHODS: Data from two 6-week, double-blind, placebo-controlled studies (n = 228) were combined, as were three 1-year, open-label studies (n = 688). Patients with DBDs and subaverage IQ, 5 to14 years, received placebo or risperidone .02 to .06 mg/kg/day. Cognitive measures included the Continuous Performance Task (CPT) and Verbal Learning Test for Children (VLT-C). Efficacy was assessed using the Nisonger Child Behavior Rating Form (NCBRF). Adverse events were collected via spontaneous report; sedation was assessed using visual analog scale. RESULTS: Improvements on the NCBRF Conduct Problem subscale were significantly greater for risperidone- versus placebo-treated patients (-15.8 vs. -6.4, p < .0001) in short-term studies; significant reductions were observed in long-term studies (-16.3, p < .0001). No overall decline and some significant improvement in attention (CPT) and memory (VLT-C) were noted regardless of treatment in short-term studies. VLT-C improved significantly (p < .0001) for both groups, with no difference between treatment groups. Improvements in memory (VLT-C) and attention (CPT) were noted in long-term studies. Somnolence/sedation did not affect cognitive function. CONCLUSIONS: Cognitive function was not altered by risperidone in short-term studies and was maintained or improved with one year of treatment in children with DBDs and subaverage IQ, potentially representing age-appropriate gains. 相似文献
77.
Richard T. Silver MD 《Current hematologic malignancy reports》2007,2(1):43-46
Polycythemia vera is a myeloproliferative disease, which, if untreated, leads to thrombohemorrhagic complications and eventually
to progressive myelofibrosis, anemia, and splenomegaly. Two newly available drugs, interferon alfa and imatinib mesylate,
may alter the course of this disease. Used as single agents, each produces lasting remissions in about 75% of patients with
polycythemia vera. Of significance, change in JAK2 expression has been reported after treatment with both agents. 相似文献
78.
79.
Terry Joe Sprinkle Julia F. Agee Russell B. Tippins C. Richard Chamberlain Guy B. Faguet George H. DeVries 《Brain research》1987,426(2):349-357
Monoclonal antibodies against human and bovine 2′:3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) were generated by fusing FOX-NY myeloma cells with spleen cells from RBF/Dn mice previously immunized with the purified brain antigens. The enzyme isolated from bovine brain was quite basic, with an isoelectric point of 9.71 and both the bovine and human enzymes consisted of a closely spaced doublet at approximately 44 and 46 kDa on SDS-PAGE. Six monoclonals were identified as strongly recognizing the enzyme on both ELISA plates and on immunoblots of whole brain protein. Four monoclonals very weakly cross-reacted with guinea pig myelin basic protein. In contrast with two previous reports, some of our monoclonal antibodies did immunostain 2 or 3 protein bands in peripheral nerve, two bands closely corresponding to those immunostained in central nervous system (CNS) myelin, the Wolfgram protein fraction and in acetone powders of whole brain. Each of the 6 monoclonals reacting strongly on immunoblots recognized the enzyme in from 2 to 5 of the species examined (human, bovine, rat, mouse and rabbit). In addition, all 6 monoclonals that immunostained the enzyme in whole brain, myelin and Wolfgram protein immunoblots recognized both CNP1 (44 kDa) and CNP2 (46 kDa). The two closely spaced protein bands observed on SDS-PAGE and previously stained on immunoblots of CNS CNPase using polyvalent rabbit anti-bovine CNPase antisera, and now different monoclonal antibodies, appear to be immunologically related and to contain highly conserved sequences. 相似文献
80.