全文获取类型
收费全文 | 39177篇 |
免费 | 3672篇 |
国内免费 | 126篇 |
专业分类
耳鼻咽喉 | 384篇 |
儿科学 | 1385篇 |
妇产科学 | 972篇 |
基础医学 | 5539篇 |
口腔科学 | 569篇 |
临床医学 | 5432篇 |
内科学 | 8268篇 |
皮肤病学 | 831篇 |
神经病学 | 4168篇 |
特种医学 | 957篇 |
外国民族医学 | 6篇 |
外科学 | 3975篇 |
综合类 | 364篇 |
一般理论 | 17篇 |
预防医学 | 4132篇 |
眼科学 | 652篇 |
药学 | 2544篇 |
中国医学 | 47篇 |
肿瘤学 | 2733篇 |
出版年
2023年 | 316篇 |
2022年 | 442篇 |
2021年 | 1161篇 |
2020年 | 814篇 |
2019年 | 1263篇 |
2018年 | 1377篇 |
2017年 | 1096篇 |
2016年 | 1162篇 |
2015年 | 1235篇 |
2014年 | 1605篇 |
2013年 | 2184篇 |
2012年 | 3017篇 |
2011年 | 2965篇 |
2010年 | 1722篇 |
2009年 | 1587篇 |
2008年 | 2496篇 |
2007年 | 2485篇 |
2006年 | 2360篇 |
2005年 | 2267篇 |
2004年 | 2184篇 |
2003年 | 1970篇 |
2002年 | 1807篇 |
2001年 | 368篇 |
2000年 | 315篇 |
1999年 | 386篇 |
1998年 | 412篇 |
1997年 | 318篇 |
1996年 | 281篇 |
1995年 | 262篇 |
1994年 | 221篇 |
1993年 | 194篇 |
1992年 | 168篇 |
1991年 | 191篇 |
1990年 | 167篇 |
1989年 | 146篇 |
1988年 | 141篇 |
1987年 | 133篇 |
1986年 | 152篇 |
1985年 | 131篇 |
1984年 | 129篇 |
1983年 | 110篇 |
1982年 | 115篇 |
1981年 | 121篇 |
1980年 | 91篇 |
1979年 | 68篇 |
1978年 | 65篇 |
1977年 | 74篇 |
1976年 | 83篇 |
1975年 | 78篇 |
1974年 | 68篇 |
排序方式: 共有10000条查询结果,搜索用时 328 毫秒
51.
Anne?Helene?Garde ?se?Marie?Hansen Johnni?Hansen 《International archives of occupational and environmental health》2009,82(10):1219-1228
Background
Sleep problems are common effects of shift work. The aim of the present study was to evaluate how different types of shift affect sleep and sleepiness, and to relate sleepiness to urinary 6-sulfatoxymelatonin. 相似文献52.
Justine Royle Rachel Williamson Mark Strachan Marie O’Donnell Simon Jackson Thanos Argryopoulos Alan McNeill 《British journal of medical & surgical urology》2009,2(5):204-207
Emphysematous pyelonephritis is a severe life-threatening infection which continues to carry significant morbidity and mortality. We present a case recently managed at our institution by laparoscopic nephrectomy. The patient survived, and in comparison to some of the more conventionally managed patients in the literature, made an extremely speedy recovery. We would advocate this option to be seriously considered when patients are suitable and appropriately trained surgeons are available. 相似文献
53.
Nuray
. Kanbur Eudice Goldberg Leora Pinhas Robert M. Hamilton Robin Clegg Debra K. Katzman 《The International journal of eating disorders》2009,42(6):575-578
Anorexia nervosa (AN) can cause both functional and structural cardiac complications, including a variety of different conduction abnormalities. This is the first case report of symptomatic diurnal second‐degree atrioventricular (AV) block (Mobitz Type I) in an adolescent with AN. We present a 12‐year‐old girl with AN, restrictor sub‐type who reported cardiac symptoms during weight gain, at the time of the initial diagnosis of AV block. Second‐degree AV block (Mobitz Type I) is discussed as a possible complication of the AN, as well as being an intrinsic conduction system disease. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2009 相似文献
54.
Gastrojejunostomy stricture after Roux-en-Y gastric bypass occurs in 3 to 27% of morbidly obese patients in the USA. We questioned
whether preoperative patient characteristics, including demographic attributes and comorbid disease, might be significant
factors in the etiology of stricture. In this study from November 2001 to February 2006 (51 months), at a high-volume bariatric
center, of the 1,351 patients who underwent laparoscopic gastric bypass, 92 developed stricture (6.8%). All but two were treated
successfully by endoscopic dilation. All patients stopped nonsteroidal anti-inflammatory medications 2 weeks prior to surgery
and did not restart them. The operative procedure included the use of a 21-mm transoral circular stapler to create the gastrojejunostomy;
the Roux limb was brought retrogastric, retrocolic. In an effort to reduce our center’s stricture rate, late in the study,
U-clips used at the gastrojejunostomy were replaced by absorbable sutures, and postoperative H2 antagonists were added to the treatment protocol. The change to absorbable polyglactin suture proved to be significant, resulting
in a lower stricture rate. The addition of H2 antagonists showed no significant effect. Following the retrospective review of the prospective database, univariate and
multivariate logistic regression analyses identified factors associated with the development of stricture. Gastroesophageal
reflux disease and age were each shown to be statistically significant independent predictors of stricture following laparoscopic
gastric bypass.
Presented at the 2006 Annual Meeting of the Society for Surgery of the Alimentary Tract, May 20–24, Los Angeles, CA (poster
presentation). 相似文献
55.
56.
Frederica Perera Deliang Tang Robin Whyatt Sally Ann Lederman Wieslaw Jedrychowski 《Cancer epidemiology, biomarkers & prevention》2005,14(3):709-714
Polycyclic aromatic hydrocarbons (PAH), of which benzo[a]pyrene is a representative member, are combustion-related environmental pollutants and include known carcinogens. Laboratory animal studies indicate that the dose of PAHs to the fetus is on the order of a 10th that to the mother and that there is heightened susceptibility to PAH-induced carcinogenesis during the fetal and infancy periods. Carcinogen-DNA adducts, a measure of procarcinogenic genetic damage, are considered a biomarker of increased cancer risk. Here we compare the levels of benzo[a]pyrene-DNA adducts as a proxy for PAH-DNA damage measured in maternal blood and newborn cord blood obtained at delivery in four different populations of mothers (total of 867) and newborns (total of 822), representing a 30-fold range of exposure to ambient PAHs. The populations include residents in Northern Manhattan, participants in a study of the effects of the World Trade Center disaster, residents in Krakow, Poland, and residents in Tongliang, China. Mean adduct concentrations in both maternal and cord blood and the proportion of samples with detectable adducts, increased across the populations [Northern Manhattan < World Trade Center (WTC) < Krakow < Tongliang], consistent with the trend in estimated ambient exposure to PAHs (P < 0.001). For mothers, the means in the respective populations were Northern Manhattan (0.21 adducts per 10(8) nucleotides), WTC (0.23 adducts per 10(8) nucleotides), Krakow (0.28 adducts per 10(8) nucleotides), Tongliang (0.31 adducts per 10(8) nucleotides); the corresponding means in the newborns were Northern Manhattan (0.23), WTC (0.24), Krakow (0.29), Tongliang (0.31). The percentage of mothers with detectable levels of adducts in the respective populations were Northern Manhattan (36.8%), WTC (57.5%), Krakow (72.9%), Tongliang (73.4%); the corresponding percentages among the newborns were Northern Manhattan (42.4%), WTC (60.6%), Krakow (71.1%), Tongliang (79.5%). Despite the estimated 10-fold lower PAH dose to the fetus based on laboratory animal experiments, the adduct levels in the newborns were similar to or higher than in the mothers. This study suggests that the fetus may be 10-fold more susceptible to DNA damage than the mother and that in utero exposure to polycyclic aromatic hydrocarbons may disproportionately increase carcinogenic risk. The data support preventive policies to limit PAH exposure to pregnant women and children. 相似文献
57.
Daniel A. Monti Marie E. Stoner Gail Zivin Martha Schlesinger 《Journal of cancer survivorship》2007,1(2):161-166
Introduction As many as one quarter of all cancer survivors report traumatic stress symptoms from cancer-related experiences. While the
majority of these patients do not meet the criteria for posttraumatic stress disorder (PTSD), there is growing evidence that
subsyndromal symptoms can significantly contribute to functional impairment and negative health outcomes. Treatment options
for the hallmark symptoms of traumatic stress—unpleasant, intrusive thoughts and avoidant behaviors—have not been well investigated
for the cancer survivorship population.
Materials and methods Seven female cancer survivors with traumatic stress symptoms from cancer-related experiences and no other major psychopathology,
were enrolled to receive three sessions of Neuro-Emotional Technique (NET), a brief, targeted treatment that combines traditional
desensitization principles with complementary modalities.
Results Psychological outcome measures (Impact of Event Scale (IES) and Subjective Units of Distress (SUD) and physiological measures
(Heart Rate (HR) and Skin Conductance Level (SCL) demonstrated the following changes: 71% on IES, 88% SUD, 74% on HR, and
65% on SCL following the intervention. Statistically significant changes were observed for all four parameters, and effect
size g for proportion improved were 0.50 each for IES, SUD, and HR, and 0.20 for SCL.
Conclusions These cases suggest feasibility of the NET intervention for cancer-related traumatic stress and the potential for change in
symptoms and physiological reactivity. Further investigation is needed to determine the specific and long-term effects of
such an approach.
Implications for cancer survivors Traumatic stress from cancer-related experiences might represent a constellation of symptoms that are amenable to brief, targeted
interventions.
This study was supported by the O.N.E. Research Foundation 相似文献
58.
59.
60.