全文获取类型
收费全文 | 636篇 |
免费 | 54篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 124篇 |
妇产科学 | 31篇 |
基础医学 | 118篇 |
口腔科学 | 2篇 |
临床医学 | 55篇 |
内科学 | 105篇 |
皮肤病学 | 9篇 |
神经病学 | 46篇 |
特种医学 | 21篇 |
外科学 | 69篇 |
综合类 | 10篇 |
预防医学 | 20篇 |
眼科学 | 9篇 |
药学 | 21篇 |
中国医学 | 3篇 |
肿瘤学 | 41篇 |
出版年
2023年 | 6篇 |
2022年 | 6篇 |
2021年 | 23篇 |
2020年 | 13篇 |
2019年 | 15篇 |
2018年 | 23篇 |
2017年 | 20篇 |
2016年 | 24篇 |
2015年 | 15篇 |
2014年 | 25篇 |
2013年 | 28篇 |
2012年 | 30篇 |
2011年 | 32篇 |
2010年 | 20篇 |
2009年 | 12篇 |
2008年 | 30篇 |
2007年 | 41篇 |
2006年 | 34篇 |
2005年 | 27篇 |
2004年 | 24篇 |
2003年 | 20篇 |
2002年 | 25篇 |
2001年 | 13篇 |
2000年 | 17篇 |
1999年 | 14篇 |
1998年 | 9篇 |
1997年 | 4篇 |
1996年 | 6篇 |
1995年 | 6篇 |
1994年 | 9篇 |
1993年 | 4篇 |
1992年 | 12篇 |
1991年 | 12篇 |
1990年 | 5篇 |
1989年 | 6篇 |
1988年 | 4篇 |
1987年 | 8篇 |
1986年 | 3篇 |
1985年 | 8篇 |
1984年 | 5篇 |
1983年 | 5篇 |
1981年 | 4篇 |
1979年 | 10篇 |
1978年 | 4篇 |
1975年 | 8篇 |
1974年 | 4篇 |
1973年 | 5篇 |
1972年 | 2篇 |
1970年 | 2篇 |
1967年 | 2篇 |
排序方式: 共有690条查询结果,搜索用时 31 毫秒
51.
Acute interstitial nephritis (AIN) should be ruled out in children with unexplained acute renal failure. We present a 4 1/2 year old girl who presented with oliguric acute renal failure preceded by a febrile illness. Renal histopathology revealed features of drug induced AIN. She recovered with dialysis, other supportive treatment and a course of steroids. 相似文献
52.
Three affected sibs in a consanguineous family with short stature, mental retardation, downslanting palpebral fissures, ptosis and polydactyly are described. There was no hypogonadism or pigmentary retinopathy. They were thin in childhood and while two of the postpubertal sibs have a stocky build none is obese. We propose that this could be a previously unreported autosomal recessive syndrome. 相似文献
53.
Lentivirus lytic peptide 1 perturbs both outer and inner membranes of Serratia marcescens 总被引:1,自引:0,他引:1
Phadke SM Lazarevic V Bahr CC Islam K Stolz DB Watkins S Tencza SB Vogel HJ Montelaro RC Mietzner TA 《Antimicrobial agents and chemotherapy》2002,46(6):2041-2045
Bis-lentivirus lytic protein 1 (Bis-LLP1) and polymyxin B exhibited similar killing activities against Serratia marcescens. By electron microscopy, bis-LLP1 interacted with the outer and cytoplasmic bacterial membranes, while polymyxin B affected only the outer membrane. The results of standard biochemical probes supported the findings of the electron microscopy studies, suggesting that these antimicrobial peptides have different mechanisms of action. 相似文献
54.
Fibrosing mediastinitis is underdiagnosed because of the nonspecific character of the presenting symptoms. The endobronchial findings obtained via flexible bronchoscopy are not defined in the literature. We describe 3 cases of fibrosing mediastinitis, most likely caused by histoplasmosis. All 3 patients presented with hemoptysis and were found to have tracheobronchial concentric narrowing, severe hyperemia, and mucosal edema. The hyperemic blood vessels were treated with neodymium yttrium-aluminum-garnet (Nd:YAG) laser and argon plasma coagulation. We believe that recognition of specific endobronchial findings aids in prompt diagnosis of fibrosing mediastinitis. 相似文献
55.
Phadke MA Gadgil B Bharucha KE Shrotri AN Sastry J Gupte NA Brookmeyer R Paranjape RS Bulakh PM Pisal H Suryavanshi N Shankar AV Propper L Joshi PL Bollinger RC 《The Journal of nutrition》2003,133(10):3153-3157
Access to safe breast-feeding alternatives for HIV-infected mothers and their infants in many settings is limited. We compared the rates of early postpartum hospitalization of infants born to HIV-infected mothers using different infant-feeding practices in a large government hospital in Pune, India. From March 1, 2000 to November 30, 2001, infants born to HIV-infected mothers were followed in a postpartum clinic. All mothers had received a standard short course of antenatal zidovudine. Infant-feeding practices were assessed within 3 d of delivery, prior to postpartum hospital discharge. Sixty-two of 148 mothers (42%) were breast-feeding their infants. Eighty-six of the mothers (58%) were providing replacement feeding, primarily diluted cow, goat or buffalo milk (top feeding). Twenty-one of the 148 participating infants (14.2%) born during the study period required hospitalization within the 1st 6 mo of life and 6 infants required repeat hospitalization. All hospitalized infants were receiving replacement feeding with a rate of 0.093 hospitalizations per 100 person-days (95% CI, 0.062 to 0.136). The reasons for hospitalization included acute gastroenteritis (48.1%), pneumonia (18.5%), septicemia (11.1%) and jaundice (11.1%). A high risk for early postpartum hospitalization was seen in replacement-fed infants born to HIV-infected mothers in Pune, India. In settings such as India, where access to safe replacement feeding is limited, interventions making exclusive breast-feeding safer for HIV-infected mothers and infants are needed. Such interventions would be valuable additions to the very effective national prevention programs that currently rely on the provision of short-course zidovudine and nevirapine. 相似文献
56.
57.
Milk samples from 54 well-nourished urban mothers between the age of 18-36 years were studied. The birth weight of infants ranged between 2.5 to 3.9 kg at full term. The mean (g or Cal/100 ml) lactose (6.51), protein (1.08), fat (4.48) and energy contents (74.83) of milk was on par with the well-nourished mothers of developed countries. The milk fat content observed was higher than that reported in under nourished mothers from developing countries. 相似文献
58.
59.
Transfusion transmitted diseases 总被引:1,自引:0,他引:1
Transfusion transmitted disease (TTD) is a major challenge to the transfusion services all over the world. The problem of
TTD is directly proportionate to the prevalence of the infection in the blood donor community. In India, hepatitis B/C, HIV,
malaria, syphilis, cytomegalo virus, parvo-virus B-19 and bacterial infections are important causes of concern. Hepatitis
B and C infections are prevalent in India and carrier rate is about 1–5% and 1%, respectively. Post transfusion hepatitis
B/C is a major problem in India (about 10%) because of low viraemia and mutant strain undetectable by routine ELISA. HIV prevalence
among blood donors is different in various parts of the country. It may not be so alarming as projected by some agencies.
In one study from north India, confirmed HIV positivity was found in 0.2/1000 blood donor. Post transfusion CMV is difficult
to prevent but use of leukocyte filters may help to reduce it significantly. Parvo virus B-19 infection in blood donors is
39.9% which may increase morbidity in multitransfused or immunocompromised patients. Current symphilis tests may not be sensitive
but it should be continued to exclude high-risk donors. Malaria is a real problem for India due to the lack of a simple and
sensitive screening test. Incidence of bacterial contamination is greatly reduced due to improved collection/ preservation
techniques and use of antibiotics in patients. However, proper vigilance and quality control is needed to prevent this problem.
Total dependence of altruistic repeat voluntary donors and use of sensitive laboratory tests may help Indian blood transfusion
services to reduce incidences of TTDs. 相似文献
60.
Papiris SA Manali ED Kalomenidis I Kapotsis GE Karakatsani A Roussos C 《Critical care (London, England)》2007,11(3):213
The term Pulmonary-renal syndrome refers to the combination of diffuse alveolar haemorrhage and rapidly progressive glomerulonephritis. A variety of mechanisms such as those involving antiglomerular basement membrane antibodies, antineutrophil cytoplasm antibodies or immunocomplexes and thrombotic microangiopathy are implicated in the pathogenesis of this syndrome. The underlying pulmonary pathology is small-vessel vasculitis involving arterioles, venules and, frequently, alveolar capillaries. The underlying renal pathology is a form of focal proliferative glomerulonephritis. Immunofluorescence helps to distinguish between antiglomerular basement membrane disease (linear deposition of IgG), lupus and postinfectious glomerulonephritis (granular deposition of immunoglobulin and complement) and necrotizing vasculitis (pauci-immune glomerulonephritis). Patients may present with severe respiratory and/or renal failure and require admission to the intensive care unit. Since the syndrome is characterized by a fulminant course if left untreated, early diagnosis, exclusion of infection, close monitoring of the patient and timely initiation of treatment are crucial for the patient's outcome. Treatment consists of corticosteroids in high doses, and cytotoxic agents coupled with plasma exchange in certain cases. Renal transplantation is the only alternative in end-stage renal disease. Newer immunomodulatory agents such as those causing TNF blockade, B-cell depletion and mycophenolate mofetil could be used in patients with refractory disease. 相似文献