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981.
982.
Achalasia: A review of therapeutic options and outcomes 总被引:7,自引:0,他引:7
Advances in achalasia has led to the development of new therapeutic options. This review will focus on methodology and outcomes
of two established techniques; pneumatic dilation and surgical myotomy; and one new technique, LES injection of botulinum
A toxin. 相似文献
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E.C. de Ataide S. Reges Perales M.A. de Oliveira Peres L. Bastos Eloy da Costa F. Quarella F.G. Valerini F. Chueiri Neto R. Silveira Bello Stucchi I. de Fátima Santana Ferreira Boin 《Transplantation proceedings》2018,50(2):476-477
Background
Acute liver failure (ALF) is a clinical syndrome that results from the abrupt loss of liver function in a patient without previous liver disease. The most frequent causes are viral hepatitis, drug induced, and autoimmune disease, but in 20% of cases no cause is identified. Carthamus tinctorius (safflower) oil is used as a dietary supplement for weight loss and antioxidant. There are 4 cases described in the literature of ALF induced by the use of this substance. The objective of this study was to report 3 cases of ALF treated at the Clinical Hospital of the State University of Campinas that suggest the use of C tinctorius oil as a probable etiologic factor.Case Reports
The 3 patients had a diagnosis of ALF according to the King's College criteria. All had a history of ingestion of this oil for weight loss. During etiologic evaluation, viral hepatitis, autoimmune diseases, or any other drug cause were excluded, thus pointing to C tinctorius oil as the triggering factor. All 3 patients underwent liver transplantation: 2 had good postoperative evolution, and 1 died 12 days after the procedure.Conclusions
Two cases are described in which the hepatic insufficiency induced by C tinctorius oil was successfully treated through liver transplantation. This highlights the risk of misuse of this substance for weight loss. 相似文献989.
Jinous Samavat Giulia Cantini Francesco Lotti Alessandra Di Franco Lara Tamburrino Selene Degl’Innocenti Elisa Maseroli Erminio Filimberti Enrico Facchiano Marcello Lucchese Monica Muratori Gianni Forti Elisabetta Baldi Mario Maggi Michaela Luconi 《Obesity surgery》2018,28(1):69-76
Objectives
The aim of this study is to evaluate the effect of massive weight loss on the seminal parameters at 6 months from bariatric surgery.Design
Two-armed prospective study performed in 31 morbidly obese men, undergoing laparoscopic roux-en-Y-gastric bypass (n = 23) or non-operated (n = 8), assessing sex hormones, conventional (sperm motility, morphology, number, semen volume), and non-conventional (DNA fragmentation and seminal interleukin-8), semen parameters, at baseline and after 6 months from surgery or patients’ recruitment.Results
In operated patients only, a statistically significant improvement in the sex hormones was confirmed. Similarly, a positive trend in the progressive/total sperm motility and number was observed, though only the increase in semen volume and viability was statistically significant (Δ = 0.6 ml and 10%, P < 0.05, respectively). A decrease in the seminal interleukin-8 levels and in the sperm DNA fragmentation was also present after bariatric surgery, whereas these parameters even increased in non-operated subjects. Age-adjusted multivariate analysis showed that the BMI variations significantly correlated with the changes in the sperm morphology (β = ?0.675, P = 0.025), sperm number (β = 0.891, P = 0.000), and semen volume (r = 0.618, P = 0.015).Conclusion
The massive weight loss obtained with bariatric surgery was associated with an improvement in some semen parameters. The correlations found between weight loss and semen parameter variations after surgery suggest that these might occur early downstream of the testis and more slowly than the changes in the sex hormones.990.
Raquel Munhoz da Silveira Campos Ana Raimunda Dâmaso Deborah Cristina Landi Masquio Fernanda Oliveira Duarte Marcela Sene-Fiorese Antonio Eduardo AquinoJr Filippo Aragão Savioli Pamela Cristina Lopes Quintiliano Ana Claudia Pelissari Kravchychyn Liliane Isabel Guimarães Lian Tock Lila Missae Oyama Valter Tadeu Boldarine Vanderlei Salvador Bagnato Nivaldo Antonio Parizotto 《Lasers in medical science》2018,33(6):1245-1254
Investigations suggest the benefits of low-level laser therapy (LLLT) to improve noninvasive body contouring treatments, inflammation, insulin resistance and to reduce body fat. However, the mechanism for such potential effects in association with exercise training (ET) and possible implications in browning adiposity processes remains unclear. Forty-nine obese women were involved, aged between 20 and 40 years with a body mass index (BMI) of 30–40 kg/m2. The volunteers were divided into Phototherapy (808 nm) and SHAM groups. Interventions consisted of exercise training and phototherapy applications post exercise for 4 months, with three sessions/week. Body composition, lipid profile, insulin resistance, atrial natriuretic peptide (ANP), WNT5 signaling, interleukin-6 (IL-6), and fibroblast growth factor-21 (FGF-21) were measured. Improvements in body mass, BMI, body fat mass, lean mass, visceral fat, waist circumference, insulin, HOMA-IR, total cholesterol, LDL-cholesterol, triglycerides, and ANP in both groups were demonstrated. Only the Phototherapy group showed a reduction in interleukin-6 and an increase in WNT5 signaling. In addition, it was possible to observe a higher magnitude change for the fat mass, insulin, HOMA-IR, and FGF-21 variables in the Phototherapy group. In the present investigation, it was demonstrated that exercise training associated with LLLT promotes an improvement in body composition and inflammatory processes as previously demonstrated. The Phototherapy group especially presented positive modifications of WNT5 signaling, FGF-21, and ANP, possible biomarkers associated with browning adiposity processes. This suggests that this kind of intervention promotes results applicable in clinical practice to control obesity and related comorbidities. 相似文献