全文获取类型
收费全文 | 904篇 |
免费 | 46篇 |
国内免费 | 33篇 |
专业分类
儿科学 | 28篇 |
妇产科学 | 10篇 |
基础医学 | 103篇 |
口腔科学 | 46篇 |
临床医学 | 73篇 |
内科学 | 197篇 |
皮肤病学 | 17篇 |
神经病学 | 31篇 |
特种医学 | 136篇 |
外科学 | 95篇 |
综合类 | 86篇 |
预防医学 | 25篇 |
眼科学 | 3篇 |
药学 | 84篇 |
中国医学 | 4篇 |
肿瘤学 | 45篇 |
出版年
2022年 | 7篇 |
2021年 | 7篇 |
2020年 | 5篇 |
2019年 | 4篇 |
2018年 | 8篇 |
2017年 | 11篇 |
2016年 | 12篇 |
2015年 | 9篇 |
2014年 | 8篇 |
2013年 | 19篇 |
2012年 | 22篇 |
2011年 | 28篇 |
2010年 | 23篇 |
2009年 | 24篇 |
2008年 | 34篇 |
2007年 | 45篇 |
2006年 | 37篇 |
2005年 | 35篇 |
2004年 | 16篇 |
2003年 | 25篇 |
2002年 | 20篇 |
2001年 | 23篇 |
2000年 | 23篇 |
1999年 | 29篇 |
1998年 | 41篇 |
1997年 | 26篇 |
1996年 | 25篇 |
1995年 | 33篇 |
1994年 | 29篇 |
1993年 | 20篇 |
1992年 | 16篇 |
1991年 | 22篇 |
1990年 | 12篇 |
1989年 | 33篇 |
1988年 | 35篇 |
1987年 | 26篇 |
1986年 | 26篇 |
1985年 | 15篇 |
1984年 | 18篇 |
1983年 | 16篇 |
1982年 | 10篇 |
1981年 | 13篇 |
1980年 | 9篇 |
1979年 | 20篇 |
1978年 | 10篇 |
1977年 | 8篇 |
1976年 | 4篇 |
1975年 | 10篇 |
1972年 | 4篇 |
1971年 | 4篇 |
排序方式: 共有983条查询结果,搜索用时 31 毫秒
71.
Kino Y 《Nihon rinsho. Japanese journal of clinical medicine》2000,58(11):2307-2312
Inactivated influenza vaccine has been widely used; however, its effectiveness is not always perfect. To create a much better vaccine, live vaccines have been extensively investigated. Among several candidate live vaccines, cold-adapted(Ca) vaccine is the only promising candidate. According to clinical studies recently conducted in the U.S., Ca vaccine was proven to be highly effective against laboratory confirmed influenza, both in adults and children. Furthermore, Ca vaccines for the H5N1 pandemic strains were generated and their attenuation and efficacy were confirmed in experimental animals. 相似文献
72.
Tsuji Y Hamada H Kimura J Katsuki Y Kino S Yamamoto Y Ishizaki A Kassai S Suzuki K Nakasaki H Watanabe M Tsujita K Suzuki S Itou Y Kusano M 《Gan to kagaku ryoho. Cancer & chemotherapy》1999,26(12):1694-1697
This is a compilation of the results of preventive intraarterial infusion following resection of hepatic metastasis from colorectal cancer at four surgical centers. The cases studied included two groups: A) 76 patients who underwent normal liver resection only, and B) 78 patients who underwent resection with adjuvant chemotherapy. Methods included: 1) WHF, 50 cases; 2) other methods using 5-FU, 18 cases; and 3) intraarterial infusions other than 5-FU, 10 (2 cases, outcome unknown). Survival rates for groups A and B for 1 and 5 years were 71.2, 18.9% and 91.5, 56.2%, respectively, with the rates for the intraarterial infusion group showing far better results. The 1- and 5-year survival rates in terms of infusion methods were: 1) 90.7% and 64.6%; 2) 94.4% and 39.3%; and 3) 90% and 60%, respectively, showing no remarkable differences between methods. Total doses of 5-FU were (a) less than 5 g, 7 patients (b) 5-15 g, 16 patients (c) 15-30 g, 22 patients (d) greater than 30 g, 23 patients. A comparison of 1- and 5-year survival rates shows (a) 85.7% and 17.1%; (b) 66.5% and 44.3%; (c) 100% and 62.7%; (d) 100% and 66.5%, respectively, with doses (c) and (d) showing markedly better results than the (a) dosage. From this we conclude that the group undergoing intraarterial hepatic infusion had a markedly improved prognosis compared to the group not undergoing any type of adjuvant therapy. Also, groups receiving a dosage of 15 g or greater of 5-FU showed prolonged survival rates. 相似文献
73.
Y Yamamoto A Kakisaka M Minami J Goto K Ohara A Isizaki S Kino T Kono S Kasai 《Gan to kagaku ryoho. Cancer & chemotherapy》1999,26(8):1159-1162
To clarify the effect of high-dose 5-FU injection into the hepatic artery (1,000 mg/m2 weekly) on liver metastases of colorectal cancer, the peripheral venous 5-FU concentration was measured in two groups of patients, one which had undergone hepatectomy and the other which had not. The area under the concentration-time curve (AUC) was calculated and the preventive effect of 5-FU on extrahepatic lesions was examined. The peripheral venous 5-FU concentration and AUC were higher in patients who received the drug via the hepatic artery after hepatectomy, and 5-FU was effective for the prevention of extrahepatic lesions as well as against recurrence in the residual liver. 相似文献
74.
PC Morris JN Cawson GS Balasubramaniam 《Journal of Medical Imaging and Radiation Oncology》1999,43(1):12-15
Two cases of epidermal cyst of the breast, a rare benign condition, were detected during a 3-year period in a mammographic screening programme, from 57 954 screening examinations. It is not uncommon for epidermal cysts to be initially misdiagnosed. The mammographic, ultrasound and histological features are presented. It is recommended that these lesions be resected because they possibly have malignant potential. 相似文献
75.
The authors studied 54 patients with multisystem trauma, including blunt chest injury, using combined dynamic first-pass and electrocardiographically (ECG) gated radionuclide ventriculography (RNV) to evaluate for posttraumatic myocardial dysfunction. Twenty-six of 54 (48%) patients had abnormalities of ventricular wall motion. The ventricular dysfunction was confined to the right ventricle in 92% of cases. In general, abnormalities consisted of right ventricular dilatation and diffuse hypokinesia, although in seven cases there were localized wall-motion abnormalities. The right ventricular ejection fraction of those patients with wall-motion abnormalities was significantly lower than those with normal studies. Left ventricular ejection fraction did not differ significantly between these groups. ECG changes were not associated with the cardiac dysfunction demonstrated scintigraphically, nor was there a relationship between the number or type of extrathoracic or thoracic injuries demonstrated by RNV. Follow-up studies obtained in 15 cases showed a significant overall improvement in cardiac function by 3 weeks after injury. Combined first-pass and ECG-gated RNV is useful for the identification and follow-up of patients with posttraumatic cardiac dysfunction. 相似文献
76.
Radiologically guided balloon catheters were used to dilate 94 gastrointestinal strictures in 92 patients over a 6-year period. Fifty strictures were esophageal and 44 nonesophageal (22 gastroenterostomies, 11 antral-pyloric strictures, four colorectal strictures, four enteroenterostomies, and three miscellaneous strictures). Factors influencing the success of stricture intubation included patient age, stricture location (esophageal vs. nonesophageal and proximal vs. distal esophageal), and association with a surgical anastomosis. Malignancy was associated with greater postdilation irregularity and a smaller increase in stricture diameter, as measured radiographically. Procedural failures occurred in 8% of cases (2% of esophageal and 30% of nonesophageal lesions). Two small, asymptomatic mucosal tears were seen after dilation (one esophageal and one colonic); no other procedural complications occurred. Following successful dilation, 16 patients (17%; six with esophageal and ten with non-esophageal strictures) had recurrence of symptoms during short-term (30-day) follow-up. 相似文献
77.
78.
FK 506: historical perspectives. 总被引:5,自引:0,他引:5
T Goto T Kino H Hatanaka M Okuhara M Kohsaka H Aoki H Imanaka 《Transplantation proceedings》1991,23(6):2713-2717
79.
80.