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121.
Amano K Takamatsu J Ogata A Miyazaki C Kaneyama H Katsuragi S Deshimaru M Sumiyoshi S Miyakawa T 《Psychiatry and clinical neurosciences》2000,54(1):17-22
In order to clarify the characteristics of epilepsy in patients with severe mentally retarded (SMR) subjects, we analyzed 52 SMR subjects with epilepsy from the institute for SMR subjects at Kikuchi National Hospital, Kumamoto, Japan. A total of 61.5% patients had uncontrolled seizures which were resistant to treatment. The most common combinations of seizure types in those not responding to conventional anticonvulsants were generalized tonic-clonic seizures (GTCS) with tonic seizure and GTCS with atypical absence. Their clinical features were characterized by spastic paralysis associated with a slower background electroencephalogram and abnormal computed tomography scans of the head, suggesting the involvement of cortical damage. These findings suggest that a large proportion of epilepsy in SMR subjects does not respond to treatment and that the severity of organic brain damage may therefore affect the natural course of epilepsy in such patients. 相似文献
122.
Katsumi Monoo Masato Sageshima Eiko Ito Shigeki Nishihira Kazuo Ishikawa 《Nihon Jibiinkoka Gakkai kaiho》2003,106(3):192-198
In the 22 years between March 1979 and February 2001, we treated 16 patients--10 men and 6 women aged 10-80 years (mean: 44 years)--with mucoepidermoid carcinoma (MEC) of the salivary gland, evaluating them clinically and histopathologically. Tumor sites included 12 at the parotid gland, 3 at the submandibular gland, and 1 at the minor salivary gland. All tumors were graded histopathologically based on the criteria of Goode et al. as follows: low grade (n = 10), intermediate grade (n = 1), and high grade (n = 5). Female gender was associated with low grade MEC and male gender with high grade MEC (P < 0.05). The age at onset in high grade MEC was older than that in low grade MEC (P < 0.005). Lymph-node metastasis was detected in 7 out of the 16 patients (44%) associated significantly with high grade MEC (P < 0.05). Distant metastasis was detected in 4 of 16 patients (25%). Distant metastasis was significantly associated with high grade MEC (P < 0.05). Local recurrence was detected in 3 of 15 patients undergoing surgery (20%). No difference was seen in local recurrence frequency between low and high grade MEC. Survival was calculated with Kaplan-Meier's method. In all 16, 5-year survival was 86% and 10-year survival 75%. Five-year survival in low grade MEC was 100%, whereas that in high grade MEC was 67% (P < 0.05). In MEC of the salivary gland, it was suggested that the histopathological MEC grade evaluated by Goode's criteria significantly correlated with gender, age, lymph-node metastasis, distant metastasis, and 5-year survival. 相似文献
123.
Naoki Matsushiro Takashi Sato Takako Iwaki Katsumi Doi Takeshi Kubo 《Nihon Jibiinkoka Gakkai kaiho》2003,106(3):211-219
Six cochlear implant recipients with hearing aids in the opposite ear were studied to survey binaural advantage. They were examined in separate tests by using a hearing aid alone, cochlear implant alone, and by using both devices (bimodal condition). Test items used were the Japanese monosyllable word list 67--S and Japanese HINT. Statistically significantly results were obtained in the bimodal condition, three out of six subjects were successful in the monosyllable word test and all successful in the Japanese HINT. We conclude that all subjects enjoyed binaural advantage in speech perception in bimodal condition with no conflict at the recognition level; even when different sounds from cochlear implant and contralateral hearing aid were received. The plasticity of the brain is thought to be of importance in the bimodal condition. 相似文献
124.
F. Numa K. Umayahara H. Ogata S. Nawata Y. Sakaguchi T. Emoto K. Kawasaki H. Hirakawa M. Sase A. Oga† & H. Kato 《International journal of gynecological cancer》2003,13(3):364-367
Abstract. Numa F, Umayahara K, Ogata H, Nawata S, Sakaguchi Y, Emoto T, Kawasaki K, Hirakawa H, Sase M, Oga A, Kato H. De novo uterine sarcoma with good response to neoadjuvant chemotherapy. We report here the extremely rare case of a 28-year-old woman with advanced stage uterine sarcoma arising soon after a cesarean section. She underwent an abdominal cesarean section because of a breech presentation. At the time of the procedure, there were no abnormal findings such as leiomyoma of the uterus in the abdominal cavity. One year later, she was referred to our hospital because of a large abdominal tumor. Transabdominal power Doppler ultrasonography and magnetic resonance imaging (MRI) showed a large hypervascular tumor in the abdominal cavity. Her serum levels, for the two tumor markers carbohydrate antigen CA125 and LDH, were elevated, at 219 U/ml (< 35 U/ml) and 862 IU/l (115 U/ml−217 U/ml), respectively. On the basis of a diagnosis of malignant tumor of gynecological origin, exploratory laparotomy was performed, and through biopsy, the tumor was found to be advanced undifferentiated uterine sarcoma. She exhibited a good response to neoadjuvant chemotherapy consisting of cisplatin, epirubicin, and dimethyltriazenoimidazole carboxamide (DTIC) every 28 days, which was successfully followed by a hysterectomy. 相似文献
125.
Nawashiro H Nagakawa S Ono K Nakamura M Katoh H Ohnuki A Tsuzuki N Ishihara S Miyazawa T Shima K Ogata S Aida S Tokumaru A Kosuda S 《No shinkei geka. Neurological surgery》2000,28(9):823-827
We herein describe thallium-201 single photon emission tomography (T1-201 SPECT) findings in three cases with intracranial angioma. One of the lesions which was associated with chronic encapsulated intracerebral hematoma showed moderate accumulation of T1-201, but, others demonstrated no accumulation. The usefulness and limitations of T1-201 SPECT in differential diagnosis of intracranial mass lesions are discussed. 相似文献
126.
127.
Ogata T Kurabayashi M Hoshino YI Sekiguchi KI Kawai-Kowase K Ishikawa S Morishita Y Nagai R 《Transplantation》2000,70(11):1653-1656
128.
Expression and functional analyses of breast cancer resistance protein in lung cancer. 总被引:12,自引:0,他引:12
129.
Ishidoya S Fukuzaki A Kaneto H Takeda A Ogata Y Sasaki T Suzuki K Watanabe R Hoshi S Kikuya M Takeuchi K Ito S Orikasa S 《Nephron》2000,85(2):175-177
A 50-year-old woman developed renin-dependent hypertension immediately after accidental unilateral ureteral ligation during hysterectomy, and the hypertension lasted for 5 months. Surgical release of the obstruction was carried out 157 days after the ligation. Then, her blood pressure was normalized. However, the obstructed kidney showed intensive tubulointerstitial fibrosis and functional recovery was not obtained. This case suggests that the renin-angiotensin system may be upregulated in human kidney during unilateral ureteral obstruction for a long duration. 相似文献
130.
Kazuhiko Ogawa Takafumi Toita Yasumasa Kakinohana Keiichiro Yamaguchi Koichi Miyagi Toshihiko Kinjyo Katsumi Yamashiro Satoshi Sawada 《International journal of clinical oncology / Japan Society of Clinical Oncology》1997,2(2):67-72
Background This retrospective study analyzed the outcome in patients with intracranial germ-cell tumors to determine whether tumor response
during radiation therapy can predict achievement of primary local control with radiation therapy alone.
Methods Between 1983 and 1993, 22 patients with untreated primary intracranial germ cell tumors received a total whole brain radiation
dose of between 18 Gy and 45 Gy (mean 31.3 Gy) with or without a localized field of 10 to 36.4 Gy (mean, 22.4 Gy), or local
irradiation only (1 patient). In 10 patients with pineal tumor only, who were treated first with radiation therapy, tumor
response to radiation therapy was evaluated using computed tomography (CT) (at baseline, and approximately 20 Gy and 50 Gy).
Areas of calcification in the tumor were subtracted from total tumor volume. Follow-up time ranged from 2 to 12 years.
Results Five-year actuarial survival rates for patients with germinoma were 71%, 100% for patients with a teratoma component, and
100% for patients without histologic verification. Patients with germinomas or tumors suspected of being germinomas who were
given more than 50 Gy had no local relapse. There was no correlation between primary local control by radiation therapy alone
and initial tumor volume. The rate of tumor volume response to irradiation assesed by CT was significantly different in those
patients who relapsed compared to those who did not relapse
Conclusion Tumor response during radiation therapy using CT was considered to be predictive of primary local control with radiation therapy
alone. 相似文献