全文获取类型
收费全文 | 7775篇 |
免费 | 586篇 |
国内免费 | 128篇 |
专业分类
耳鼻咽喉 | 112篇 |
儿科学 | 169篇 |
妇产科学 | 116篇 |
基础医学 | 1257篇 |
口腔科学 | 197篇 |
临床医学 | 552篇 |
内科学 | 1640篇 |
皮肤病学 | 289篇 |
神经病学 | 773篇 |
特种医学 | 350篇 |
外科学 | 918篇 |
综合类 | 39篇 |
一般理论 | 1篇 |
预防医学 | 560篇 |
眼科学 | 246篇 |
药学 | 609篇 |
中国医学 | 120篇 |
肿瘤学 | 541篇 |
出版年
2024年 | 3篇 |
2023年 | 58篇 |
2022年 | 139篇 |
2021年 | 278篇 |
2020年 | 138篇 |
2019年 | 239篇 |
2018年 | 298篇 |
2017年 | 230篇 |
2016年 | 314篇 |
2015年 | 423篇 |
2014年 | 455篇 |
2013年 | 507篇 |
2012年 | 804篇 |
2011年 | 769篇 |
2010年 | 480篇 |
2009年 | 372篇 |
2008年 | 539篇 |
2007年 | 470篇 |
2006年 | 422篇 |
2005年 | 381篇 |
2004年 | 333篇 |
2003年 | 253篇 |
2002年 | 249篇 |
2001年 | 49篇 |
2000年 | 40篇 |
1999年 | 40篇 |
1998年 | 27篇 |
1997年 | 19篇 |
1996年 | 10篇 |
1995年 | 18篇 |
1994年 | 11篇 |
1993年 | 11篇 |
1992年 | 14篇 |
1991年 | 17篇 |
1990年 | 10篇 |
1989年 | 5篇 |
1988年 | 7篇 |
1987年 | 6篇 |
1986年 | 11篇 |
1984年 | 5篇 |
1983年 | 3篇 |
1982年 | 4篇 |
1981年 | 2篇 |
1979年 | 3篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1975年 | 2篇 |
1971年 | 2篇 |
1969年 | 2篇 |
1965年 | 2篇 |
排序方式: 共有8489条查询结果,搜索用时 15 毫秒
91.
92.
93.
Daniele Santetti Maria Inês de Albuquerque Wilasco Cristina Toscani Leal Dornelles Isabel Cristina Ribas Werlang Fernanda Urruth Fontella Carlos Oscar Kieling Jorge Luiz dos Santos Sandra Maria Gon?alves Vieira Helena Ayako Sueno Goldani 《World journal of gastroenterology : WJG》2015,21(29):8927-8934
AIM: To evaluate the nutritional status and its association with proinflammatory cytokines in children with chronic liver disease.METHODS: We performed a cross-sectional study with 43 children and adolescents, aged 0 to 17 years, diagnosed with chronic liver disease. All patients regularly attended the Pediatric Hepatology Unit and were under nutritional follow up. The exclusion criteria were fever from any etiology at the time of enrollment, inborn errors of the metabolism and any chronic illness. The severity of liver disease was assessed by Child-Pugh, Model for End-stage Liver Disease(MELD) and Pediatric End Stage Liver Disease(PELD) scores. Anthropometric parameters were height/age, body mass index/age and triceps skinfold/age according to World Health Organization standards. The cutoff points for nutritional status were risk of malnutrition(Z-score -1.00) and malnutrition(Z-score -2.00). Interleukin-1β(IL-1β), IL-6 and tumor necrosis factor-α levels were assessed by commercial ELISA kits. For multivariate analysis, linear regression was applied to assess the association between cytokine levels, disease severity and nutritional status. RESULTS: The median(25th-75 th centile) age of the study population was 60(17-116)-mo-old, and 53.5% were female. Biliary atresia was the main cause of chronic liver disease(72%). With respect to Child-Pugh score, cirrhotic patients were distributed as follows: 57.1% Child-Pugh A, a mild presentation of the disease, 34.3% Child-Pugh B, a moderate stage of cirrhosis and 8.6% Child-Pugh C, were considered severe cases. PELD and MELD scores were only above the cutoff point in 5 cases. IL-6 values were increased in patients at nutritional risk(34.9%) compared with those who were well-nourished [7.12(0.58-34.23) pg/m L vs 1.63(0.53-3.43) pg/m L; P = 0.02], correlating inversely with triceps skinfold-for-age z-score(rs =-0.61; P 0.001). IL-6 levels were associated with liver disease severity assessed by Child-Pugh score(P = 0.001). This association remained significant after adjusting for nutritional status in a linear regression model. CONCLUSION: High IL-6 levels were found in children with chronic liver disease at nutritional risk. Inflammatory activity may be related to nutritional status deterioration in these patients. 相似文献
94.
Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia 总被引:1,自引:0,他引:1
95.
Yong Tao Byunghak Kang Daniel A. Petkovich Yuba R. Bhandari Julie In Genevieve Stein-OBrien Xiangqian Kong Wenbing Xie Nicholas Zachos Shinji Maegawa Himani Vaidya Stephen Brown Ray-Whay Chiu Yen Xiaojian Shao Jai Thakor Zhihao Lu Yi Cai Yuezheng Zhang Hariharan Easwaran 《Cancer cell》2019,35(2):315-328.e6
96.
97.
98.
99.