全文获取类型
收费全文 | 4725篇 |
免费 | 268篇 |
国内免费 | 35篇 |
专业分类
耳鼻咽喉 | 78篇 |
儿科学 | 123篇 |
妇产科学 | 82篇 |
基础医学 | 523篇 |
口腔科学 | 40篇 |
临床医学 | 313篇 |
内科学 | 1236篇 |
皮肤病学 | 40篇 |
神经病学 | 380篇 |
特种医学 | 204篇 |
外科学 | 984篇 |
综合类 | 48篇 |
预防医学 | 219篇 |
眼科学 | 79篇 |
药学 | 296篇 |
中国医学 | 12篇 |
肿瘤学 | 371篇 |
出版年
2023年 | 21篇 |
2022年 | 81篇 |
2021年 | 136篇 |
2020年 | 70篇 |
2019年 | 100篇 |
2018年 | 139篇 |
2017年 | 109篇 |
2016年 | 117篇 |
2015年 | 137篇 |
2014年 | 174篇 |
2013年 | 206篇 |
2012年 | 301篇 |
2011年 | 325篇 |
2010年 | 186篇 |
2009年 | 158篇 |
2008年 | 232篇 |
2007年 | 230篇 |
2006年 | 231篇 |
2005年 | 223篇 |
2004年 | 209篇 |
2003年 | 185篇 |
2002年 | 162篇 |
2001年 | 120篇 |
2000年 | 113篇 |
1999年 | 91篇 |
1998年 | 37篇 |
1997年 | 32篇 |
1996年 | 31篇 |
1995年 | 31篇 |
1994年 | 23篇 |
1992年 | 58篇 |
1991年 | 48篇 |
1990年 | 52篇 |
1989年 | 42篇 |
1988年 | 53篇 |
1987年 | 50篇 |
1986年 | 34篇 |
1985年 | 48篇 |
1984年 | 32篇 |
1983年 | 34篇 |
1982年 | 21篇 |
1981年 | 20篇 |
1979年 | 50篇 |
1978年 | 31篇 |
1977年 | 21篇 |
1976年 | 23篇 |
1975年 | 23篇 |
1974年 | 29篇 |
1973年 | 33篇 |
1972年 | 24篇 |
排序方式: 共有5028条查询结果,搜索用时 0 毫秒
51.
Go Anan Hiromichi Iwamura Jotaro Mikami Yuki Kohada Jun Ito Yasuhiro Kaiho Makoto Sato 《Translational andrology and urology》2021,10(2):775
BackgroundHolmium laser enucleation of the prostate (HoLEP) has been a widely utilized minimally invasive surgical procedure for benign prostate hyperplasia. The current study aimed to compare surgical outcomes and King’s Health Questionnaire (KHQ) assessment scores following HoLEP between younger men and those aged ≥75 years.MethodsThis prospective single-center study compared perioperative complications, postoperative urinary conditions, and KHQ scores (nine categories) between men aged ≥75 years (group A) and men aged <75 years (group B) before and 1, 3, and 6 months after surgery.ResultsA total of 100 patients were included for analysis (group A, n=38 and group B, n=62). No differences in patient backgrounds, perioperative complications, such as perioperative decrease in hemoglobin, postoperative fever, postoperative indwelling catheterization duration, or postoperative hospitalization duration, and KHQ were observed between both groups. Both groups showed significantly better International Prostate Symptom Scores, quality of life, maximum urinary flow rate, and postvoid residual volume 1, 3, and 6 months after HoLEP compared to their respective preoperative levels (P<0.01). Regarding KHQ categories, both groups showed significantly better general health perceptions, impact on life, emotions, and sleep/energy 1 month after HoLEP; role limitations, physical limitations, and social limitations 3 months after HoLEP; and personal relationships and incontinence severity measures 6 months after HoLEP compared to their respective preoperative levels (P<0.05).ConclusionsHoLEP could be safe and effective even for men aged ≥75 years, comparing complications, urinary condition, and KHQ scores. 相似文献
52.
53.
Kuroda T Go G Ojima S Nishi S Mizuno K 《Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.]》1993,2(4):221-224
Isolated avulsion fractures of the lesser tuberosity are extremely rare. A 24-year-old woman fell on her back as her arm was forcibly extended and adducted. Radiographs revealed a small fragment of bone beneath the glenoid. Axillary radiography showed the bone fragment and a bone defect of the lesser tuberosity. Computed tomography scan clearly demonstrated those findings. Surgery was performed 3 weeks after the occurrence of the injury. The bone fragment was reduced and fixed by means of two screws. After 3 weeks, light exercise was started. At follow-up 7 months later she had no complaints. Most reported cases involved sudden contraction of the subscapularis tendon. This type of fracture is sometimes misdiagnosed; computed tomography scan is useful for diagnosis. Previously reported cases have similarly demonstrated a good outcome after surgery, except in cases involving children. 相似文献
54.
55.
Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line 总被引:14,自引:0,他引:14
Estrogens, whether natural or synthetic, clearly influence reproductive development, senescence, and carcinogenesis. Pyrethroid insecticides are now the most widely used agents for indoor pest control, providing potential for human exposure. Using the MCF-7 human breast carcinoma cell line, we studied the estrogenic potential of several synthetic pyrethroid compounds in vitro using pS2 mRNA levels as the end point. We tested sumithrin, fenvalerate, d-trans allethrin, and permethrin. Nanomolar concentrations of either sumithrin or fenvalerate were sufficient to increase pS2 expression slightly above basal levels. At micromolar concentrations, these two pyrethroid compounds induced pS2 expression to levels comparable to those elicited by 10 nM 17ss-estradiol (fivefold). The estrogenic activity of sumithrin was abolished with co-treatment with an antiestrogen (ICI 164,384), whereas estrogenic activity of fenvalerate was not significantly diminished with antiestrogen co-treatment. In addition, both sumithrin and fenvalerate were able to induce cell proliferation of MCF-7 cells in a dose-response fashion. Neither permethrin nor d-trans allethrin affected pS2 expression. Permethrin had a noticeable effect on cell proliferation at 100 microM, whereas d-trans allethrin slightly induced MCF-7 cell proliferation at 10 microM, but was toxic at higher concentrations. Overall, our studies imply that each pyrethroid compound is unique in its ability to influence several cellular pathways. These findings suggest that pyrethroids should be considered to be hormone disruptors, and their potential to affect endocrine function in humans and wildlife should be investigated. 相似文献
56.
57.
58.
59.
M Go?ebiowska I Ligenza I Kobierska E Zielińska J Wlaz?owski P Sikora K Ha?adaj 《Ginekologia polska》1992,63(5):221-226
1110 neonates, from 30 to 42 of estimated gestational age (EGA) were measured on the 1st day of life to estimate upper mid-arm circumference (MAC) and head circumference (HC). Individual MAC/HC ratio was calculated. MAC/HC ratio was used to estimate gestational age and nutritional status of the newborns. We proved that MAC/HC ratio increased linearly between 30 and 38 week of pregnancy and it stabilized between 38-42 week. We compared MAC/HC ratio with birth weight, skin fold score, and ponderal index. We concluded that this ratio may be very useful to estimate gestational age and to include the neonates to "the group of risk". 相似文献
60.
Jerzy Silberring Waldemar Gołda Zbigniew Szybinski 《European journal of nuclear medicine and molecular imaging》1976,1(3):155-158
In this paper attempts were made towards the optimalization and the control of some parameters of the RIA reaction.Basing on the law mass action, as well as on the Scatchard's and Sips's equations, the equilibrium constants for the reversible reaction: insulin-125I-antibody for different incubation temperatures were calculated. Moreover a characteristic of the antiinsulin antibody by means of the heterogeneity coefficient was done, as well as the values of the thermodynamic function increments were calculated, which made possible to point out explicitly the optimal shape of the standard curve. 相似文献