全文获取类型
收费全文 | 2593篇 |
免费 | 208篇 |
国内免费 | 32篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 82篇 |
妇产科学 | 107篇 |
基础医学 | 306篇 |
口腔科学 | 34篇 |
临床医学 | 217篇 |
内科学 | 746篇 |
皮肤病学 | 61篇 |
神经病学 | 156篇 |
特种医学 | 195篇 |
外科学 | 176篇 |
综合类 | 45篇 |
一般理论 | 3篇 |
预防医学 | 241篇 |
眼科学 | 21篇 |
药学 | 139篇 |
肿瘤学 | 302篇 |
出版年
2021年 | 32篇 |
2020年 | 15篇 |
2019年 | 39篇 |
2018年 | 42篇 |
2017年 | 26篇 |
2016年 | 29篇 |
2015年 | 44篇 |
2014年 | 53篇 |
2013年 | 70篇 |
2012年 | 119篇 |
2011年 | 138篇 |
2010年 | 66篇 |
2009年 | 65篇 |
2008年 | 134篇 |
2007年 | 147篇 |
2006年 | 109篇 |
2005年 | 97篇 |
2004年 | 96篇 |
2003年 | 90篇 |
2002年 | 79篇 |
2001年 | 76篇 |
2000年 | 65篇 |
1999年 | 71篇 |
1998年 | 51篇 |
1997年 | 43篇 |
1996年 | 46篇 |
1995年 | 20篇 |
1994年 | 32篇 |
1993年 | 21篇 |
1992年 | 61篇 |
1991年 | 61篇 |
1990年 | 64篇 |
1989年 | 56篇 |
1988年 | 56篇 |
1987年 | 66篇 |
1986年 | 60篇 |
1985年 | 51篇 |
1984年 | 48篇 |
1983年 | 40篇 |
1982年 | 29篇 |
1981年 | 21篇 |
1980年 | 18篇 |
1979年 | 22篇 |
1978年 | 18篇 |
1977年 | 20篇 |
1976年 | 23篇 |
1975年 | 12篇 |
1974年 | 27篇 |
1973年 | 21篇 |
1972年 | 13篇 |
排序方式: 共有2833条查询结果,搜索用时 15 毫秒
81.
Arthur R. Menezes Carl J. Lavie Richard V. Milani Daniel E. Forman Marjorie King Mark A. Williams 《Progress in cardiovascular diseases》2014
Coronary heart disease (CHD) is a significant cause of morbidity and mortality in the United States (US). In addition to this, many of the risk factors of CHD, such as obesity, sedentary lifestyle, diabetes mellitus, and poor nutrition, are disproportionately high in the US. Despite the many known benefits of cardiac rehabilitation (CR), referral and participation rates in these programs are paradoxically low. Over the course of this review, we will discuss some of the many benefits of CR, some of the risk factors for CHD in the US, and factors that affect referral and participation in these programs. 相似文献
82.
83.
84.
85.
Armenian SH Sun CL Francisco L Baker KS Weisdorf DJ Forman SJ Bhatia S 《Bone marrow transplantation》2012,47(2):283-290
Patients undergoing hematopoietic cell transplantation (HCT) are at increased risk of chronic health conditions, including second malignant neoplasms and cardiovascular disease. Little is known about health behaviors and cancer screening practices among HCT survivors that could moderate the risk of these conditions. The BM transplant survivor study examined health behaviors and cancer screening practices in individuals who underwent HCT between 1976 and 1998, and survived 2+ years. Health behavior was deemed as high risk, if an individual was a current smoker and if they reported risky alcohol intake (≥4 drinks per day (males), ≥3 drinks per day (females)) on days of alcohol consumption. Cancer screening assessment was per American Cancer Society recommendations. There were 1040 survivors: 42.7% underwent allogeneic HCT; 43.8% were female; median time from HCT: 7.4 years (range 2.0-27.7 years). Median age at study participation: 43.8 years (range 18.3-73.0 years). Multivariate regression analysis revealed younger age (<35 years) at study participation (Odds ratio (OR)=4.7; P<0.01) and lower education (相似文献
86.
Ibrahim Aldoss Raju Pillai Dongyun Yang Lixin Yang Shukaib Arslan Sally Mokhtari Monzr M. Al Malki Amandeep Salhotra Shilpa Shahani Haris Ali Matthew Mei Andrew Artz David Snyder Michelle Afkhami Saro Armenian Anthony Stein Guido Marcucci Stephen J. Forman Ryotaro Nakamura Vinod Pullarkat 《Blood cancer journal》2021,11(7)
87.
88.
89.
90.
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions 总被引:23,自引:0,他引:23
下载免费PDF全文
![点击此处可从《The American journal of pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Cairns NJ Neumann M Bigio EH Holm IE Troost D Hatanpaa KJ Foong C White CL Schneider JA Kretzschmar HA Carter D Taylor-Reinwald L Paulsmeyer K Strider J Gitcho M Goate AM Morris JC Mishra M Kwong LK Stieber A Xu Y Forman MS Trojanowski JQ Lee VM Mackenzie IR 《The American journal of pathology》2007,171(1):227-240
TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of sporadic and familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions (FTLD-U) with or without motor neuron disease (MND). Thus, TDP-43 defines a novel class of neurodegenerative diseases called TDP-43 proteinopathies. We performed ubiquitin and TDP-43 immunohistochemistry on 193 cases of familial and sporadic FTLD with or without MND. On selected cases, immunoelectron microscopy and biochemistry were performed. Clinically defined frontotemporal dementias (FTDs) included four groups: 1) familial FTD with mutations in progranulin (n = 36), valosin-containing protein (n = 5), charged multivesicular body protein 2B (n = 4), and linked to chromosome 9p (n = 7); 2) familial cases of FTD with unknown gene association (n = 29); 3) sporadic FTD (n = 72); and 4) familial and sporadic FTD with MND (n = 40). Our studies confirm that the spectrum of TDP-43 proteinopathies includes most cases of sporadic and familial FTLD-U with and without MND and expand this disease spectrum to include reported families with FTD linked to chromosome 9p but not FTD with charged multivesicular body protein 2B mutations. Thus, despite significant clinical, genetic, and neuropathological heterogeneity of FTLD-U, TDP-43 is a common pathological substrate underlying a large subset of these disorders, thereby implicating TDP-43 in novel and unifying mechanisms of FTLD pathogenesis. 相似文献