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排序方式: 共有291条查询结果,搜索用时 0 毫秒
41.
R C Ballard H G Fehler P Fotheringham E E Sutter J D Treharne 《Social science & medicine (1982)》1983,17(22):1755-1765
Trachoma remains the most common cause of preventable blindness in certain areas of the northern Transvaal region of South Africa. Results of epidemiological studies in the area indicate that trachoma is a familial disease with young children acting as the main source of infection within the family. Elderly women who have lived in these areas for long periods of time are at greater risk of blindness and impaired vision from the disease. Genital tract carriage of Chlamydia trachomatis is relatively infrequent in these trachoma-endemic areas and no evidence of eye-to-eye transmission of oculo-genital serotypes of C. trachomatis could be demonstrated. 相似文献
42.
André S Khayat Adriana C Guimarães Danielle Q Calcagno Aline D Seabra Eleonidas M Lima Mariana F Leal Mário HG Faria Silvia HB Rabenhorst Paulo P Assumpção Samia Demachki Marília AC Smith Rommel R Burbano 《BMC gastroenterology》2009,9(1):55-7
Background
This study evaluates the existence of numerical alterations of chromosome 17 and TP53 gene deletion in gastric adenocarcinoma. The p53 protein expression was also evaluated, as well as, possible associations with clinicopathological characteristics. 相似文献43.
Samuel Lee Rong Lu Jochen Müller‐Ehmsen Robert HG Schwinger Klara Brixius 《Clinical and experimental pharmacology & physiology》2010,37(12):1134-1138
1. There is evidence that different aetiologies of heart failure, especially ischaemic vs dilated cardiomyopathy (ICM and DCM, respectively), may influence the prognosis of patients with this disease. Patients with ICM have a worse prognosis than those with DCM; the mechanisms underlying this difference have not yet been clarified. The aim of the present study was to investigate whether there are changes in myofibrillar function depending on the aetiology of human heart failure. 2. Ca2+‐dependent tension (DT) and actomyosin ATPase acitivity (MYO) in Triton X‐skinned fibre preparations of the left ventricular myocardium from patients with heart failure due to ICM (n = 5) and DCM (n = 5) were measured. Tension‐dependent ATP consumption was calculated by the ratio of DT and MYO (‘tension cost’). Non‐failing myocardium (NF) from donor hearts, which could not be transplanted because of technical reasons, was evaluated as a control. 3. Although DT was reduced, the myofibrillar Ca2+ sensitivity of DT and MYO, as well as tension cost, were increased in preparations from ICM and DCM myocardium compared with NF. The Ca2+ sensitivity of DT and MYO was significantly increased in ICM compared with DCM preparations, resulting in more economic cross‐bridge cycling in ICM than in DCM. 4. In conclusion, ICM is associated with an increased Ca2+ sensitivity of myofibrillar tension and ATPase activity accompanied by decreased tension cost compared with DCM. Thus, the worse prognosis associated with ICM does not seem to be due to differences in myofibrillar function. 相似文献
44.
45.
Ulrike C Ryll Ann-Christin Eliasson Carolien HG Bastiaenen Dido Green 《Physical & occupational therapy in pediatrics》2019,39(2):168-180
Aims: To explore the validity of change scores of the Children's Hand-use Experience Questionnaire (CHEQ). Methods: Analysis of the CHEQ included 44 children (15 girls) between 6–16 years (median 9.0; IQR 8–11) with unilateral cerebral palsy, with baseline and post- (two-week intensive) intervention assessments using the Goal Attainment Scale (GAS) as external anchor for change. Hypotheses on the magnitude of expected change were formulated and correlation coefficients and effect sizes calculated. Receiver operating curve analysis was performed and the area under the curve (AUC) calculated to investigate the ability of CHEQ to discriminate between improvement and non-improvement according to GAS. Results: All hypotheses about the magnitude of change were confirmed supporting longitudinal validity of CHEQ scales to measure change in the perception of bimanual performance. AUCs for the Grasp efficacy and the Time utilization were slightly below, and for the Feeling bothered slightly above the threshold. The latter one accurately discriminating between children that improved and did not improve according to the GAS. Conclusions: Evidence was found that CHEQ scales capture change in bimanual performance but with limited accuracy for two out of three scales. The validity of CHEQ change scores needs to be further explored in a wider population. 相似文献
46.
47.
深静脉血栓形成(DVT)的年发病率为48-182/10万,一般估计为1/1000。DVT病死率为1%-5%,发病率和病死率与年龄密切相关。慢性疼痛、肿胀、偶尔腿部皮肤溃疡等血栓后综合征见于1/3发生过DVT的患者。血栓后综合征可出现较早,也可迟至10年才出现,总的发病率为2年23%,5年28%。患者如使用弹力加压袜至少2年以上,腿部病变的发生率可 相似文献
48.
Syphilis serology in patients with primary syphilis and non-treponemal sexually transmitted diseases in southern Africa. 下载免费PDF全文
A Sischy F da L''Exposto Y Dangor H G Fehler F Radebe D D Walkden S D Miller R C Ballard 《Sexually transmitted infections》1991,67(2):129-132
The reactivity of a non-specific reagin (RPR) test and a specific treponemal (FTA-ABS) test were determined in 21 patients with primary syphilis, 430 patients with proven non-treponemal genital ulcerations and 719 patients with acute urethritis presenting at a clinic for sexually transmitted diseases in southern Africa. Excluding those 21 cases of primary syphilis, 358 of 1149 tests performed (31%) were found to be reactive by at least one test. The rate of false positive RPR tests was very low (0.02%). Significantly higher rates of seropositivity were detected in patients with genital ulcerations than in patients with acute urethritis. The highest rates were detected among patients with proven lymphogranuloma venereum (34% RPR positive, FTA-ABS positive; 19% RPR negative, FTA-ABS positive). The geometric mean titres (GMT) of positive RPR tests in non-treponemal infections were found to be lower than in darkfield positive cases of genital ulcer disease. 相似文献
49.
Mandy B Belfort John AF Zupancic Katherine M Riera Jane HG Turner Lisa A Prosser 《BMC pediatrics》2011,11(1):12
Background
Childhood obesity is a substantial public health problem. The extent to which health state preferences (utilities) are related to a child's weight status has not been reported. The aims of this study were (1) to use a generic health state classification system to measure health related quality of life and calculate health utilities in a convenience sample of children and adolescents and (2) to determine the extent to which these measures are associated with weight status and body mass index (BMI). 相似文献50.
Soh KC Tay KH Tan BS Mm Htoo A Hg Lo R Lin SE 《Cardiovascular and interventional radiology》2008,31(3):604-609
Our aim was to review our experience with percutaneous antegrade ureteric stent (PAUS) placement and to determine if the routinely
conducted check nephrostogram on the day following ureteric stent placement was necessary. Retrospective review of patients
who had undergone PAUS placement between January 2004 and December 2005 was performed. There were 83 subjects (36 males, 47
females), with a mean age of 59.9 years (range, 22–94 years). Average follow-up duration was 7.1 months (range, 1–24 months).
The most common indications for PAUS placement were ureteric obstruction due to metastatic disease (n = 56) and urinary calculi (n = 34). Technical success was 93.2% (96/103 attempts), with no major immediate procedure-related complications or mortalities.
The Bard 7Fr Urosoft DJ Stent was used in more than 95% of the cases. Eighty-one of 89 (91.0%) check nephrostograms demonstrated
a patent ureteric stent with resultant safety catheter removal. Three check nephrostograms revealed distal stent migration
requiring repositioning by a goose-snare, while five others showed stent occlusion necessitating permanent external drainage
by nephrostomy drainage catheter reinsertion. Following PAUS placement, the serum creatinine level improved or stabilized
in 82% of patients. The serum creatinine outcome difference between the groups with benign and malignant indications for PAUS
placement was not statistically significant (p = 0.145) but resolution of hydronephrosis was significantly better (p = 0.008) in patients with benign indications. Percutaneous antegrade ureteric stent placement is a safe and effective means
of relief for ureteric obstruction. The check nephrostogram following ureteric stent placement was unnecessary in the majority
of patients. 相似文献