排序方式: 共有103条查询结果,搜索用时 31 毫秒
91.
Shikha Rao MBBS FAAD David Goldberg MD JD FAAD 《Journal of Cosmetic Dermatology》2023,22(10):2765-2768
Background
Neck skin is thinner and has a more delicate dermal layer than facial skin. The studied product was specifically formulated for the neck combining a hydrating delivery system with a trifunctional corrective technology composed of 0.2% pure retinol, 2.5% tripeptide concentrate, and 5.0% glaucine complex to help improvement in signs of aging.Objectives
To evaluate cosmetic and histologic changes 3 months after treatment using immunostains for Type I collagen, Type III collagen, and glycosaminoglycan (GAGS). In addition, overall clinical improvement in photoaged skin was measured by both Griffith's photonumeric photoaging scale, photographic improvement, and questionnaires.Methods
This study was an open-label, blinded clinical trial evaluating a combined retinol, tripeptide, and glaucine containing cream in the treatment of photo-aged skin. The study enrolled a total of 20 healthy male or female subjects, who applied the product for 3 months to their face and neck.Results
Clinical as well histologic changes were consistent with improvement in all 20 subjects.Conclusion
Use of a combined retinol, tripeptide, and glaucine containing cream led to both clinical and histologic improvement of phototoaging. 相似文献92.
David J. Goldberg MD JD Anneke Andriessen PhD Ashish C. Bhatia MD FAAD Michael H. Gold MD FAAD Amy B. Lewis MD Margarita S. Lolis MD FAAD Jason H. Miller MD FAAD Adriana Ros MD FAAD 《Journal of Cosmetic Dermatology》2023,22(11):3026-3032
Introduction
Acne is the most common reason for dermatology consultation in adolescents and young adults. Consultation is often delayed despite unsuccessful self-treatment. Postponing effective treatment places acne sufferers at higher risk for permanent acne scars and post-inflammatory pigment changes.Aim
This review discusses clinical challenges with present therapeutic options for acne treatment and the role of a 1726 nm laser for acne.Methods
Current acne treatment guidelines were reviewed. A literature review was conducted for trials of light-based acne therapy. The selectivity of previous light-based therapies was reviewed.Results
Available acne therapy is effective, but treatment-related side effects are common. Acne treatment guidelines do not include recommendations for light-based treatments. Different types of light-based treatments have been tried but until now no wavelength specifically targeted sebaceous glands.Conclusion
The 1726 nm laser is safe and effective for treating mild to severe acne in all Fitzpatrick skin types. Acne resolution is apparent within the first month and improves for up to 2 years beyond treatment. 相似文献93.
Michael Gold MD FAAD Yoon-Soo Cindy Bae MD FAAD David J. Goldberg MD JD FAAD Sumayah Jamal MD PhD Amy B. Lewis MD Shari Marchbein MD FAAD Adriana Ros DO Uma Santhanam PhD Lisa DiNatale Jaime Emmetsberger PhD 《Journal of Cosmetic Dermatology》2023,22(12):3313-3319
Background
There is an increasing demand for facial skin rejuvenation. Specialized aesthetic skincare treatments may be one of the first steps to help prevent or treat facial signs of aging. This article discusses aesthetic skin care for facial skin rejuvenation, particularly data on two creams containing Macrocystis pyrifera ferment.Methods
The authors convened a dermatology advisory board to discuss challenges and practices in using skincare for facial rejuvenation, combining their expert opinion and experience on facial rejuvenation with preclinical and clinical data on two creams containing Macrocystis pyrifera ferment and a review of the literature.Results
Preclinical and clinical studies on Macrocystis pyrifera ferment and two creams containing the ferment exhibit anti-inflammatory, anti-aging, and healing properties. In preclinical studies, the ferment demonstrated collagen type I enhancing properties in ex vivo skin models, and skin cells treated with the ferment migrated faster than untreated cells in the in vitro study. In clinical studies measuring visible anti-inflammatory activity, the ferment alone and the ferment-containing products significantly decreased erythema, and in anti-aging studies, they improved visible skin aging parameters. Finally, in clinical studies on the stratum corneum, the two creams increased moisture levels and decreased transepidermal water loss (TEWL), reflecting healing by enhancing barrier strength and recovery.Conclusions
The Macrocystis pyrifera ferment and creams containing the ferment are effective skin care treatment products to decrease the visible effects of inflammation and signs of aging while promoting healing by enhancing barrier resilience and recovery. 相似文献94.
95.
96.
Sabrina Guillen Fabi MD FAAD FAACS Je-Young Park MD Wilson W. S. Ho MBChB FRCSEd Vasanop Vachiramon MD Steve Dayan MD 《Journal of Cosmetic Dermatology》2023,22(6):1805-1813
Background
The unique anatomy of the Asian face, along with the influence of cultural forces and regional preferences, has led to the development of specialized approaches to rejuvenation and beautification that are applicable to the aesthetic practice within Asia as well as those who serve these patients internationally.Aims
To discuss similarities and differences in anatomy and treatment preferences of Asian patients and explore how these differences may influence aesthetic practices.Patients/Methods
In support of clinicians who wish to serve a diverse patient population, a six-part international roundtable series focused on diversity in aesthetics was conducted from August 24, 2021 to May 16, 2022.Results
The results of the sixth and final roundtable in the series, the Asian Patient, are described here. Anatomical differences and their influence on treatment preferences are discussed, and specific procedural information provided for management of facial shape and projection, including advanced injection techniques for the eyelid-forehead complex.Conclusions
The continued exchange of ideas and treatment techniques support not only optimal aesthetic outcomes for a diverse range of patients within a given practice, but also the evolution of aesthetic medicine. The expert approaches detailed here may be used to inform treatment plans tailored to the Asian population. 相似文献97.
James Fanning MD Carolyn Jacob MD FAAD Isabel Diaz BA Omer Ibrahim MD FAAD 《Journal of Cosmetic Dermatology》2023,22(11):3033-3041
Chemical peeling treats facial cutaneous aging and may avoid risks in patients with sensitive skin, darker skin types, limited finances, or concern for side effects of other resurfacing techniques. Tolerability and improvement of photoaging using a combination peel containing 6% trichloroacetic acid and 12% lactic acid for treatment of mild-to-moderate signs of facial photoaging were assessed. This is a prospective, single-center, single-arm, study of 32 female subjects with mild-to-moderate signs of facial aging and Fitzpatrick Skin Types I–V treated with three monthly treatments of a combination peel containing 6% trichloroacetic acid and 12% lactic acid. After 3 treatments, there were statistically significant improvements in clarity, brightness, redness, pigmentation, fine lines, tactile and visual roughness, and overall appearance scores. Subjective improvements in photoaging parameters varied from 53% (fine lines) to 91% (clarity/brightness). Three treatments with a combination peel containing 6% trichloroacetic acid and 12% lactic acid achieved improvements in signs of facial photoaging. This procedure is safe and effective at treating cutaneous aging for all skin types and a viable option for patients who wish to avoid other resurfacing techniques such as laser resurfacing, microneedling among others. 相似文献
98.
Antoine Salloum MD Nagham Bazzi MD Stephen Squires MD Thomas Chu MD Paul Benedetto MD FAAD Anthony Benedetto DO FACP FACMS 《Journal of Cosmetic Dermatology》2023,22(3):921-931
Introduction
Xenografts are a now a cornerstone in the management of wound dressings. Promising results were achieved since 1960 in the application of skin substitute for skin defects.Objective
The objective of this study was to evaluate the efficacy of various xenografts.Methods
A literature research was conducted using the following query: ‘Porcine skin dermatology substitute’, ‘bovine skin dermatology substitute’, ‘xenograft skin substitute dermatology’, ‘xenografts skin defect’, ‘porcine skin defect’, ‘bovine skin defect’.Results
The review yielded 35 articles pertaining to the topic. Main indications for porcine and bovine xenograft application were burn wounds and post-traumatic wounds, respectively. Mean discharge date or length of stay was at the 6th day after porcine application, and the time of graft healing was reported for 33.7% (n = 510) of patients. Promising results were seen with Matriderm and split-thickness skin graft. Most wounds achieved an excellent cosmetic result with full range of motion and a smooth contour appearance. A great variety of tissue substitutes exist, and the choice of graft application should depend on a patient's factors, product availability, wound type, size, and physician's factors.Conclusion
In summary, xenografts are more economic and affordable but have higher risk of infections compared to allografts. 相似文献99.
David Goldberg MD FAAD Amogh Kothare MS Margot Doucette BSc Arshdeep Kaur MS Stephen Ronan MD Jeffrey Fromowitz MD FAAD Amer Hamidi-Sakr PhD 《Journal of Cosmetic Dermatology》2023,22(2):486-496
Background
Selective photothermolysis on sebaceous glands is an effective method for treating acne vulgaris (AV); however, safety, efficacy, and discomfort hinder its utilization in clinical settings.Aims
The primary objective is to evaluate the safety and efficacy of a novel 1726 nm laser with contact cooling to treat AV.Methods
Seventeen patients aged 18 to 36 were enrolled and treated in this IRB-approved, single-center, open-label study. Patients received up to three facial laser sessions up to seven weeks apart. Follow-up visits happened ten days post-session and at the 4 and 12 weeks following the final session. The investigator assessed the severity of device-related adverse events (AEs). Investigator Global Assessment (IGA) and inflammatory lesion counts (ILC) were used as metrics to evaluate acne resolution and skin condition enhancement. Patients' perspectives on satisfaction and comfort using this technology were assessed using Subject Experience Questionnaires (SEQ).Results
Safety assessment showed mild and transient AEs. All subjects tolerated anesthetics-free treatments well, with a mean treatment discomfort score of 4.9 ± 1.5. Compared to baseline, a statistically significant reduction in ILC (p = 0.003) of 52% to 56% is achieved four to twelve weeks following treatment. Long-term follow-ups showed progressive improvement 24 months post-treatment with a 97% reduction in ILC. SEQs revealed high subject satisfaction (71%) with psychosocial improvement three months post-treatment.Conclusion
The novel 1726 nm laser appears safe and effective for treating mild-to-severe acne. Acne resolution is apparent within the first month and progresses beyond the study duration. 相似文献100.
Anant Patil MD Jun Lu MD FAAD Martin Kassir MD Mahsa Babaei MD Mohamad Goldust MD 《Journal of Cosmetic Dermatology》2023,22(2):395-401