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41.
42.
深静脉血栓形成(DVT)的年发病率为48-182/10万,一般估计为1/1000。DVT病死率为1%-5%,发病率和病死率与年龄密切相关。慢性疼痛、肿胀、偶尔腿部皮肤溃疡等血栓后综合征见于1/3发生过DVT的患者。血栓后综合征可出现较早,也可迟至10年才出现,总的发病率为2年23%,5年28%。患者如使用弹力加压袜至少2年以上,腿部病变的发生率可 相似文献
43.
Yurdakul P Dalton J Beattie L Brown N Erguven S Maroof A Kaye PM 《The American journal of pathology》2011,179(1):23-29
Progressive splenomegaly is a hallmark of visceral leishmaniasis in humans, canids, and rodents. In experimental murine visceral leishmaniasis, splenomegaly is accompanied by pronounced changes in microarchitecture, including expansion of the red pulp vascular system, neovascularization of the white pulp, and remodeling of the stromal cell populations that define the B-cell and T-cell compartments. Here, we show that Ly6C/G(+) (Gr-1(+)) cells, including neutrophils and inflammatory monocytes, accumulate in the splenic red pulp during infection. Cell depletion using monoclonal antibody against either Ly6C/G(+) (Gr-1; RB6) or Ly6G(+) (1A8) cells increased parasite burden. In contrast, depletion of Ly6C/G(+) cells, but not Ly6G(+) cells, halted the progressive remodeling of Meca-32(+) and CD31(+) red pulp vasculature. Strikingly, neither treatment affected white pulp neovascularization or the remodeling of the fibroblastic reticular cell and follicular dendritic cell networks. These findings demonstrate a previously unrecognized compartment-dependent selectivity to the process of splenic vascular remodeling during experimental murine visceral leishmaniasis, attributable to Ly6C(+) inflammatory monocytes. 相似文献
44.
Isguven P Arslanoglu I Mesutoglu N Yildiz M Erguven M 《European journal of pediatrics》2008,167(11):1263-1268
There is a tendency to adiposity in patients with congenital adrenal hyperplasia (CAH) despite physiological corticosteroid
doses. This study investigated body fatness in children with CAH under corticosteroid replacement therapy. Seventeen children
with CAH (female:male, 9:8; age range 1.6–10.5 years) and 18 controls (female:male, 9:9; age range 1.4–10.2 years) were studied.
Serum lipids, leptin, insulin, anthropometry, body circumferences, skinfold thickness, and body fat ratio as measured with
bioelectrical impedance analysis (BIA) were the study parameters. Weight standard deviation scores (SDS), body mass index
(BMI), BMI–SDS, body circumferences, skinfold thickness, and body fat ratio were higher and leptin was positively correlated
with all of the body circumference and skinfold thickness parameters as well as body fat ratio in the study group. Waist/hip
ratio was lower in the study group. Body fatness is a serious problem starting in early childhood in CAH patients and further
refinement of the glucocorticoid replacement regimens as well as lifestyle measures are needed. 相似文献
45.
46.
Notalgia paresthetica is an isolated mononeuropathy involving the skin over or near the scapula. The cause remains unknown. We histologically observed a significant increase in the number of dermal nerves in a case of notalgia paresthetica. Immunohistochemical examination using a neural marker, S-100, positively stained the nerves. Interestingly, a biopsy from perilesional skin also showed an abnormal nerve proliferation. 相似文献
47.
Mandy B Belfort John AF Zupancic Katherine M Riera Jane HG Turner Lisa A Prosser 《BMC pediatrics》2011,11(1):12
Background
Childhood obesity is a substantial public health problem. The extent to which health state preferences (utilities) are related to a child's weight status has not been reported. The aims of this study were (1) to use a generic health state classification system to measure health related quality of life and calculate health utilities in a convenience sample of children and adolescents and (2) to determine the extent to which these measures are associated with weight status and body mass index (BMI). 相似文献48.
Soh KC Tay KH Tan BS Mm Htoo A Hg Lo R Lin SE 《Cardiovascular and interventional radiology》2008,31(3):604-609
Our aim was to review our experience with percutaneous antegrade ureteric stent (PAUS) placement and to determine if the routinely
conducted check nephrostogram on the day following ureteric stent placement was necessary. Retrospective review of patients
who had undergone PAUS placement between January 2004 and December 2005 was performed. There were 83 subjects (36 males, 47
females), with a mean age of 59.9 years (range, 22–94 years). Average follow-up duration was 7.1 months (range, 1–24 months).
The most common indications for PAUS placement were ureteric obstruction due to metastatic disease (n = 56) and urinary calculi (n = 34). Technical success was 93.2% (96/103 attempts), with no major immediate procedure-related complications or mortalities.
The Bard 7Fr Urosoft DJ Stent was used in more than 95% of the cases. Eighty-one of 89 (91.0%) check nephrostograms demonstrated
a patent ureteric stent with resultant safety catheter removal. Three check nephrostograms revealed distal stent migration
requiring repositioning by a goose-snare, while five others showed stent occlusion necessitating permanent external drainage
by nephrostomy drainage catheter reinsertion. Following PAUS placement, the serum creatinine level improved or stabilized
in 82% of patients. The serum creatinine outcome difference between the groups with benign and malignant indications for PAUS
placement was not statistically significant (p = 0.145) but resolution of hydronephrosis was significantly better (p = 0.008) in patients with benign indications. Percutaneous antegrade ureteric stent placement is a safe and effective means
of relief for ureteric obstruction. The check nephrostogram following ureteric stent placement was unnecessary in the majority
of patients. 相似文献
49.
患者为1例39岁女性,患T/NK细胞淋巴瘤,在外周血异基因干细胞移植后15天,发生环孢素A(CSA)毒性相关的微血管病溶血性贫血(MAHA).因血清肌酐从移植前的0.4mg/dL,上升至移植后第9和15天的1.0和2.9 mg/dL.故停用CSA. 相似文献
50.
c-kit expression in human megakaryoblastic leukemia cell lines 总被引:1,自引:0,他引:1