首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1324323篇
  免费   87469篇
  国内免费   3005篇
耳鼻咽喉   19718篇
儿科学   44771篇
妇产科学   38075篇
基础医学   198095篇
口腔科学   35689篇
临床医学   111989篇
内科学   263441篇
皮肤病学   33841篇
神经病学   106041篇
特种医学   49767篇
外国民族医学   385篇
外科学   194078篇
综合类   25031篇
一般理论   448篇
预防医学   100842篇
眼科学   31670篇
药学   90259篇
  3篇
中国医学   2691篇
肿瘤学   67963篇
  2021年   10048篇
  2019年   10796篇
  2018年   17346篇
  2017年   12722篇
  2016年   13898篇
  2015年   18337篇
  2014年   22838篇
  2013年   34638篇
  2012年   46417篇
  2011年   48148篇
  2010年   28899篇
  2009年   26145篇
  2008年   44453篇
  2007年   46793篇
  2006年   46630篇
  2005年   44772篇
  2004年   43009篇
  2003年   39545篇
  2002年   36781篇
  2001年   52313篇
  2000年   53486篇
  1999年   45269篇
  1998年   12931篇
  1997年   11728篇
  1996年   12121篇
  1995年   11815篇
  1994年   11106篇
  1993年   10370篇
  1992年   36230篇
  1991年   35011篇
  1990年   34302篇
  1989年   32847篇
  1988年   29991篇
  1987年   30063篇
  1986年   28086篇
  1985年   26947篇
  1984年   20420篇
  1983年   17189篇
  1982年   10756篇
  1979年   18709篇
  1978年   13880篇
  1977年   11722篇
  1976年   10937篇
  1975年   11581篇
  1974年   13922篇
  1973年   13509篇
  1972年   12332篇
  1971年   11482篇
  1970年   10683篇
  1969年   10221篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
42.
43.
44.
45.
Abstract

Supporting patients in making informed healthcare decisions is a cornerstone of ethical medical practice. Surgeons frequently draw for and show images to patients when consenting them for operations but the value of this practice in informed decision-making is unclear. An audit was conducted in a General Surgery Department. 244 patients completed questionnaires on the value of visual materials when giving consent for surgery. The complexity of the operations was classified into “simple”, “moderate” or “complex”. 100% of patients felt they had given informed consent to surgery. 62% of patients received at least one form of visual material during the consenting process. All patients who received a drawing, and 99% of those provided with other images, valued these resources. Visual materials were considered more useful to patients when giving consent for moderate or complex operations than simple ones. Approximately one third of patients who did not receive visual materials would have appreciated these when making an informed decision. This research highlights the value of surgeons drawing for, and providing other visual resources to, their patients as part of the consent process. There is a role for further research and training materials in drawing skills for surgeons.  相似文献   
46.
Obesity Surgery - Laparoscopic sleeve gastrectomy (LSG) is increasingly playing a key role in obesity management. Such operations, however, carry complications sometimes including leaks. The...  相似文献   
47.
Lasers in Medical Science - Studies reported the harmful effects of 2,4-D on body tissues, provoking changes in the anatomy and physiology of the kidneys, liver, and testicles. Thus, the objective...  相似文献   
48.
Background: Poor anger regulation is considered a risk factor of aggression in individuals with mild or borderline intellectual disabilities. Psychomotor therapy (PMT) targets anger regulation through body- and movement-oriented interventions. This study aims to inform practitioners on efficacy and research-base of PMT in this population.

Method: This systematic review evaluated nine studies which met inclusion criteria in terms of participants, intervention procedures, outcomes and certainty of evidence.

Results: Seven studies revealed a substantial reduction of aggressive behaviour or anger. Certainty of evidence was rated inconclusive in most cases due to absence of experimental control.

Conclusions: We can conclude that body-oriented PMT, involving progressive relaxation and meditation procedure “Soles of the Feet”, is a promising approach. However, the paucity of studies and methodological limitations preclude classifying it as an evidence-based practice. This suggests stronger methodological research and research aimed at PMT’s mechanisms of action (e.g., improved interoceptive awareness) is warranted.  相似文献   

49.
50.

Background

Resistin is an immunometabolic mediator that is elevated in several inflammatory disorders. A ligand for Toll-like receptor 4, resistin modulates the recruitment and activation of myeloid cells, notably neutrophils. Neutrophils are major drivers of cystic fibrosis (CF) lung disease, in part due to the release of human neutrophil elastase- and myeloperoxidase-rich primary granules, leading to tissue damage. Here we assessed the relationship of resistin to CF lung disease.

Methods

Resistin levels were measured in plasma and sputum from three retrospective CF cohorts spanning a wide range of disease. We also assessed the ability of neutrophils to secrete resistin upon activation in vitro. Finally, we constructed a multivariate model assessing the relationship between resistin levels and lung function.

Results

Plasma resistin levels were only marginally higher in CF than in healthy control subjects. By contrast, sputum resistin levels were very high in CF, reaching 50–100 fold higher levels than in plasma. Among CF patients, higher plasma resistin levels were associated with allergic bronchopulmonary aspergillosis, and higher sputum resistin levels were associated with CF-related diabetes. Mechanistically, in vitro release of neutrophil primary granules was concomitant with resistin secretion. Overall, sputum resistin levels were negatively correlated with CF lung function, independently of other variables (age, sex, and genotype).

Conclusions

Our data establish relationships between resistin levels in the plasma and sputum of CF patients that correlate with disease status, and identify resistin as a novel mechanistic link between neutrophilic inflammation and lung disease in CF.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号