首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   3435726篇
  免费   306032篇
  国内免费   13830篇
耳鼻咽喉   47355篇
儿科学   108925篇
妇产科学   87771篇
基础医学   549719篇
口腔科学   93074篇
临床医学   312014篇
内科学   609989篇
皮肤病学   89346篇
神经病学   297239篇
特种医学   138106篇
外国民族医学   309篇
外科学   533941篇
综合类   106050篇
现状与发展   24篇
一般理论   2265篇
预防医学   291308篇
眼科学   78707篇
药学   237524篇
  21篇
中国医学   9551篇
肿瘤学   162350篇
  2021年   55070篇
  2020年   35073篇
  2019年   58082篇
  2018年   71316篇
  2017年   53933篇
  2016年   59631篇
  2015年   73737篇
  2014年   108085篇
  2013年   173128篇
  2012年   92215篇
  2011年   92134篇
  2010年   116543篇
  2009年   120994篇
  2008年   79225篇
  2007年   82390篇
  2006年   93023篇
  2005年   88535篇
  2004年   90515篇
  2003年   81432篇
  2002年   70574篇
  2001年   111131篇
  2000年   104714篇
  1999年   102276篇
  1998年   66192篇
  1997年   63800篇
  1996年   62007篇
  1995年   57759篇
  1994年   51771篇
  1993年   48371篇
  1992年   73582篇
  1991年   70284篇
  1990年   66597篇
  1989年   65179篇
  1988年   60445篇
  1987年   59110篇
  1986年   55947篇
  1985年   56039篇
  1984年   50459篇
  1983年   45792篇
  1982年   42556篇
  1981年   39978篇
  1980年   37689篇
  1979年   41813篇
  1978年   36597篇
  1977年   33147篇
  1976年   30503篇
  1975年   29051篇
  1974年   30328篇
  1973年   29089篇
  1972年   27074篇
排序方式: 共有10000条查询结果,搜索用时 93 毫秒
171.
Erosive pustular dermatosis of the scalp (EPDS) is an uncommon chronic inflammatory response to scalp trauma that usually resolves with cicatricial alopecia. It most commonly affects elderly patients with a history of actinic damage. Herein, we describe a 16‐year‐old girl with acrofacial dysostosis type 1 presenting after surgery with crusting purulent scalp lesions, whose clinical presentation and histopathologic findings were consistent with EPDS. A review of the literature on EPDS in children is also detailed.  相似文献   
172.
173.
174.
175.
176.

Objective

Comparative survival between neoadjuvant chemotherapy and adjuvant chemotherapy for patients with cT2-4N0-1M0 non–small cell lung cancer has not been extensively studied.

Methods

Patients with cT2-4N0-1M0 non–small cell lung cancer who received platinum-based chemotherapy were retrospectively identified. Exclusion criteria included stage IV disease, induction radiotherapy, and targeted therapy. The primary end point was disease-free survival. Secondary end points were overall survival, chemotherapy tolerance, and ability of Response Evaluation Criteria In Solid Tumors response to predict survival. Survival was estimated using the Kaplan–Meier method, compared using the log-rank test and Cox proportional hazards models, and stratified using matched pairs after propensity score matching.

Results

In total, 330 patients met the inclusion criteria (n = 92/group after propensity-score matching; median follow-up, 42 months). Five-year disease-free survival was 49% (95% confidence interval, 39-61) for neoadjuvant chemotherapy versus 48% (95% confidence interval, 38-61) for adjuvant chemotherapy (P = .70). On multivariable analysis, disease-free survival was not associated with neoadjuvant chemotherapy or adjuvant chemotherapy (hazard ratio, 1.1; 95% confidence interval, 0.64-1.90; P = .737), nor was overall survival (hazard ratio, 1.21; 95% confidence interval, 0.63-2.30; P = .572). The neoadjuvant chemotherapy group was more likely to receive full doses and cycles of chemotherapy (P = .014/0.005) and had fewer grade 3 or greater toxicities (P = .001). Response Evaluation Criteria In Solid Tumors response to neoadjuvant chemotherapy was associated with disease-free survival (P = .035); 15% of patients receiving neoadjuvant chemotherapy (14/92) had a major pathologic response.

Conclusions

Timing of chemotherapy, before or after surgery, is not associated with an improvement in overall or disease-free survival among patients with cT2-4N0-1M0 non–small cell lung cancer who undergo complete surgical resection.  相似文献   
177.
178.
179.
180.
Metabolism describes the series of chemical reactions that are concerned with the provision of energy to biological systems. They may be divided into reactions involved in energy yield (catabolism: demand exceeds supply), and energy storage (anabolism: supply exceeds demand). Regulation of these pathways is critical for homeostasis, and derangements in metabolism are seen in a wide variety of pathological processes. Understanding metabolism is key to the treatment of many diseases, notably diabetes, as well as underpinning clinical nutritional support.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号