全文获取类型
收费全文 | 1409333篇 |
免费 | 115653篇 |
国内免费 | 3330篇 |
专业分类
耳鼻咽喉 | 18371篇 |
儿科学 | 46556篇 |
妇产科学 | 41067篇 |
基础医学 | 200865篇 |
口腔科学 | 37740篇 |
临床医学 | 126057篇 |
内科学 | 284497篇 |
皮肤病学 | 33370篇 |
神经病学 | 116945篇 |
特种医学 | 53855篇 |
外国民族医学 | 464篇 |
外科学 | 210598篇 |
综合类 | 32757篇 |
现状与发展 | 3篇 |
一般理论 | 487篇 |
预防医学 | 110078篇 |
眼科学 | 31493篇 |
药学 | 98582篇 |
1篇 | |
中国医学 | 3347篇 |
肿瘤学 | 81183篇 |
出版年
2021年 | 10856篇 |
2019年 | 11672篇 |
2018年 | 16590篇 |
2017年 | 12684篇 |
2016年 | 14278篇 |
2015年 | 16018篇 |
2014年 | 22576篇 |
2013年 | 33423篇 |
2012年 | 45410篇 |
2011年 | 47955篇 |
2010年 | 28172篇 |
2009年 | 27067篇 |
2008年 | 44348篇 |
2007年 | 46840篇 |
2006年 | 47409篇 |
2005年 | 45883篇 |
2004年 | 43764篇 |
2003年 | 41703篇 |
2002年 | 40219篇 |
2001年 | 73031篇 |
2000年 | 74545篇 |
1999年 | 61569篇 |
1998年 | 17001篇 |
1997年 | 15442篇 |
1996年 | 15585篇 |
1995年 | 14795篇 |
1994年 | 13405篇 |
1993年 | 12588篇 |
1992年 | 45860篇 |
1991年 | 43500篇 |
1990年 | 41508篇 |
1989年 | 39566篇 |
1988年 | 36203篇 |
1987年 | 35372篇 |
1986年 | 32883篇 |
1985年 | 31298篇 |
1984年 | 23836篇 |
1983年 | 20039篇 |
1982年 | 12215篇 |
1981年 | 10790篇 |
1979年 | 20708篇 |
1978年 | 14583篇 |
1977年 | 12085篇 |
1976年 | 11368篇 |
1975年 | 11622篇 |
1974年 | 13996篇 |
1973年 | 13535篇 |
1972年 | 12635篇 |
1971年 | 11472篇 |
1970年 | 10913篇 |
排序方式: 共有10000条查询结果,搜索用时 375 毫秒
911.
Knowledge of the health status of, and patterns of health care service utilization by rural Australian communities, is scant. This deficiency limits attempts to formulate policies designed to bring about efficient, effective and equitable delivery of health care services. This article reports the results of a health interview survey conducted in the Wimmera region of Victoria during spring 1984. The results demonstrate not only that patterns of morbidity in rural areas differ from the Australian average, but also that the health status of rural dwellers is worse than that of most Australians. Evidence suggests that while accessibility is not the most significant determinant of utilization of health care services, distance from services does affect propensity to use them. 相似文献
912.
Pharmacological properties of fluphenazine-mustard, an irreversible calmodulin antagonist 总被引:1,自引:0,他引:1
We describe an improved synthesis and properties of fluphenazine-mustard, a potent phenothiazine having an alkylating chlorethylamine chain in its structure. The drug possesses anticalmodulin activity equivalent to the parent compound, but unlike fluphenazine dihydrochloride, the mustard derivative irreversibly antagonizes the ability of calmodulin to activate cyclic nucleotide phosphodiesterase. This property is partially calcium-dependent and can be overcome by coincubation with excess fluphenazine dihydrochloride. The compound irreversibly inactivated calmodulin when incubated with intact cells and caused single-stranded breakage of DNA. Fluphenazine-mustard possesses potent antiproliferative and cytotoxic properties against malignant cell lines that are likely to be mediated through both of these actions. 相似文献
913.
914.
915.
Long-term dialysis patients frequently develop acquired renal cystic disease (ARCD). The discovery of ARCD and renal cell carcinoma in one of our hemodialysis patients led us to review the literature. ARCD has been described mainly in the maintenance hemodialysis (MH) population. Therefore, we investigated 20 peritoneal dialysis (PD) patients for ARCD using ultrasonography. Seven patients (35%) had detectable cysts and two patients (10%) had multiple bilateral cysts. One patient had a large asymptomatic complex cyst that proved to be an adenocarcinoma. Our study suggests that ARCD is relatively common in the PD population, and we speculate that it may be related more to length of time in end-stage renal disease (ESRD) than to the mode of dialysis. The potential for malignant change appears to justify a routine screening examination with ultrasonography and/or computerized tomography (CT) to detect this recently described and probably underrecognized entity. 相似文献
916.
917.
BILLY C. ROVER DMD CARL J. TOGA DMD JUDITH A. JONES DDS MPH 《Special care in dentistry》1987,7(2):70-72
Modern medicine has made many advances in the capability to sustain life. The dental profession needs to keep up to date with these changes and be creative in caring for these individuals who are medically compromised and who require special care.11 This sometimes requires the purchase of new equipment; other times it means modifying that which exists. In all instances, the level of care for these individuals requires a team approach and mandates education of all team members. In the case presented, the medical problems necessitated such a team effort to achieve optimal care. 相似文献
918.
Hypomagnesemia due to isolated renal magnesium loss was demonstrated in two unrelated families with autosomal dominant mode of inheritance. Magnesium infusions performed in two patients showed not only a reduced renal magnesium threshold but also a lowered renal tubular maximum for magnesium. All members of both families who presented with hypomagnesemia had also a lowered excretion of calcium in the urine, presumably as a consequence of increased reabsorption in Henle's loop. 相似文献
919.
The 5-year results of a randomized trial of adjuvant radiation therapy after chemotherapy in breast cancer patients treated with mastectomy 总被引:4,自引:0,他引:4
K L Griem I C Henderson R Gelman D Ascoli B Silver A Recht R L Goodman S Hellman J R Harris 《Journal of clinical oncology》1987,5(10):1546-1555
The use of adjuvant radiation therapy in breast cancer patients treated with mastectomy and adjuvant chemotherapy has been controversial. In order to assess the necessity and effectiveness of adjuvant radiation therapy in this setting, we reviewed the results in 510 patients with T1-T3 tumors and pathologically positive nodes or tumors larger than 5 cm and negative nodes who were treated with adjuvant chemotherapy. Patients with four or more positive nodes or at least one positive apical node were randomized to receive either five or ten cycles of cyclophosphamide/Adriamycin (Adria Laboratories, Columbus, OH) (CA) and patients with one to three positive nodes or operable tumors larger than 5 cm and pathologically negative nodes were randomized to receive eight cycles of either cyclophosphamide, methotrexate, and 5-fluorouracil (5-FU) (CMF) or methotrexate and 5-FU (MF) chemotherapy. Two hundred six of these patients were subsequently rerandomized to receive either no further treatment or adjuvant radiotherapy. Thirty-five patients withdrew after randomization, including 34 who declined to receive radiotherapy. Radiation therapy consisted of 4,500 cGy in 5 weeks to the chest wall and appropriate draining lymph nodes. Median follow-up from chemotherapy randomization is 45 months for patients in the CA arm and 53 months for those in the CMF/MF arm. The crude rate of local failure (chest wall or draining lymph node areas) as first site of failure for patients randomized to receive chemotherapy only was 14%; for those randomized to receive both chemotherapy and radiotherapy it was 5% (P = .03). For patients in the CMF/MF arm, the rate of local failure as the first site of failure was nearly the same for patients randomized to chemotherapy only as for those randomized to adjuvant radiotherapy as well (5% v 2%). For patients in the CA arm, the crude rate of local failure was 20% for patients randomized to receive chemotherapy only, and 6% for those randomized to both types of adjuvant treatment (P = .03). Among the 43 patients treated with CA who actually received radiotherapy, there was only one local failure, compared with 12 local failures among the 59 patients (20%) who actually did not receive radiotherapy (P = .007). No significant difference was seen in disease-free survival or overall survival in either the CA or the CMF/MF arm between patients randomized to receive radiation therapy and those randomized to no further treatment.(ABSTRACT TRUNCATED AT 400 WORDS) 相似文献
920.
MALCOLM CLARKE M.B. F.R.C.P. ALBERT ALLEN 《Journal of cardiovascular electrophysiology》1987,1(5):388-395
The facility of direct real-time endocardial electrogram recording offered by newer pacemaker models can be helpful in the assessment of normal pacemaker function. Confirmation of the main hallmarks of sensing (amplitude, slew rate, and timing of the electrogram) can be achieved. Assessment of pacing capture also can be made; techniques for further analysis using external signal averaging can enhance this. The measurement of atrial and ventricular electrograms by telemetry has led to alterations in the protocol used at implantation to allow for the input impedance of the sensing circuit of the pacemaker. Accurate measurements of retrograde VA conduction times and confirmation of normal upper rate limit behavior of ODD pacemakers can be achieved simply and reliably using telemetered electrograms from the permanent pacemaker system. 相似文献