首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   96715篇
  免费   6686篇
  国内免费   1150篇
耳鼻咽喉   863篇
儿科学   3015篇
妇产科学   2583篇
基础医学   12836篇
口腔科学   1573篇
临床医学   8898篇
内科学   22115篇
皮肤病学   1836篇
神经病学   9834篇
特种医学   2781篇
外国民族医学   2篇
外科学   10407篇
综合类   2368篇
现状与发展   2篇
一般理论   44篇
预防医学   7149篇
眼科学   1429篇
药学   7789篇
  8篇
中国医学   1081篇
肿瘤学   7938篇
  2023年   968篇
  2022年   1852篇
  2021年   3954篇
  2020年   2369篇
  2019年   2837篇
  2018年   3141篇
  2017年   2552篇
  2016年   2759篇
  2015年   3204篇
  2014年   4155篇
  2013年   5201篇
  2012年   7239篇
  2011年   7301篇
  2010年   4071篇
  2009年   3601篇
  2008年   5759篇
  2007年   5794篇
  2006年   5275篇
  2005年   4893篇
  2004年   4483篇
  2003年   3944篇
  2002年   3573篇
  2001年   1661篇
  2000年   1527篇
  1999年   1488篇
  1998年   769篇
  1997年   608篇
  1996年   540篇
  1995年   447篇
  1994年   424篇
  1993年   346篇
  1992年   765篇
  1991年   650篇
  1990年   604篇
  1989年   621篇
  1988年   527篇
  1987年   485篇
  1986年   460篇
  1985年   373篇
  1984年   341篇
  1983年   277篇
  1982年   197篇
  1981年   161篇
  1980年   149篇
  1979年   240篇
  1978年   159篇
  1977年   144篇
  1974年   141篇
  1973年   144篇
  1972年   136篇
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
141.
Ultrafiltration and solute transport during 60-min peritoneal dialyses of normal rabbits with intraperitoneal administration of phosphatidylcholine were compared to control values. The ultrafiltration rate of 0.27 mL/Kg/min did not increase when phosphatidylcholine was added. This agent had no effect on the ultrafiltration coefficient, sodium mass transport or solute clearances. Previously reported beneficial results with this agent could be due to repletion of a deficiency or an effect of the organic solvent. More studies of safety and efficacy of phosphatidylcholine are warranted before widespread clinical use.  相似文献   
142.
Sir, We are writing to provide some clarifications on the EditorialComment by Drüeke et al. [1]. We would have been happyto provide these very same clarifications had we been fairlyinvited to do so before the publication of the article. First of all, we would like to  相似文献   
143.
144.
145.
OBJECTIVE: Constitutional delay of puberty (CDP) is the absence of secondary sexual features in otherwise healthy girls past the 13th year of life. The aim of the present work was to follow the development of estrogen-dependent sexual features, determine the concentrations of gonadotropins, estradiol and sex hormone-binding globulin (SHBG) in girls with CDP at menarche and compare the findings with normal controls. METHODS: We enrolled 11 girls with CDP and 40 controls. Primary, secondary and tertiary sexual features were studied at menarche +/- 3 months. The size of the ovaries and uterus was measured using transabdominal ultrasound. Maturation of breasts and pubic hair was staged according to Tanner. Concentrations of gonadotropins (follicle-stimulating hormone (FSH), luteinizing hormone) and estradiol were measured with immunoenzymatic methods. For measurement of SHBG, a radioimmunoassay was applied. RESULTS: Menarche in CDP girls usually appeared with Stage IV or V of breast development and Stage IV of pubic hair development according to Tanner. CDP girls demonstrated a significantly smaller volume of the uterine body at menarche compared with controls (p = 0.0004). Significantly lower levels of FSH (p = 0.0363) and estradiol (p = 0.0332), as well as a tendency towards lower levels of SHBG, were revealed in CDP girls at menarche. CONCLUSION: In CDP girls, menarche is accompanied by more mature tertiary sexual features, apparently resulting from longer exposure of estrogen-dependent tissues to the action of bioactive endogenous estrogens. The smaller volume of the uterine body in CDP girls at menarche may be attributed to decreased concentrations of FSH and estradiol, as well as to the possibility of decreased insulin-like growth factor-1 and increased neuropeptide Y levels.  相似文献   
146.
黄华  邸颖 《中国疗养医学》2007,16(3):130-131
目的分析对比不同时期军队疗养员消化性溃疡(PU)的患病情况。方法采用相同的病史采集和问卷调查法,以胃镜检查资料为确诊手段,对1990年和2005年两个年度的疗养员进行消化性溃疡流行病学调查。结果1990年军队疗养员消化性溃疡的患病率为158/1168人(13.53%);2005年为56/1239人(4.52%),二者相比有显著性差异P〈0.01。结论由于保健意识、生活方式和药物治疗的干预,十五年间,军队疗养员消化性溃疡的发病率显著下降。  相似文献   
147.
Summary The chromophore-modified derivative of doxorubicin, 4-demethyl-6-0-methyl-doxorubicin, has been tested for antitumor activity in a range of experimental murine tumor systems. In contrast to the inactive 6-0-methyl derivative of daunorubicin, 4-demethyl-6-0-methyl-doxorubicin provided antitumor effects comparable to that of the parent compound. In addition, detailed DNA-interaction studies showed that the doxorubicin derivative retains the ability to bind DNA by the intercalation mechanism. However, the binding affinity was appreciably reduced following structural modification in the anthraquinone chromophore. On the basis of the proposed models of intercalation, these results could be rationalized in terms of steric influence of the bulky methoxy group. The results of this study are in agreement with the correlation already observed between DNA binding and relative antitumor activity of anthracyclines.  相似文献   
148.
采用小猪双侧颈动脉结扎伴失血模型检测双侧颈动脉的结扎伴失血对脑氧分压和O-酪氨酸变化的影响,结果发现小猪脑氧分压为(51±4)托.颈动脉结扎和失血后60min降为(10±1.5)托(P<0.001),当颈动脉恢复通畅和失血再灌注后,脑氧分压增至(40±6)托,此值与预试验时的脑氧分压无明显差异.对照组中脑纹状体中的O-酪氨酸的含量为(0.57±0.19)nmoles/g组织.缺血试验后1h其含量明显升为(29±0.5)nmoles/g组织(P<0.005),显示缺血后再灌注导致脑纹状体O-酪氨酸显著上升.提示组织中羟基产生增加,可能与新生小猪脑缺血和再灌注损伤有一定作用.  相似文献   
149.
Global migration from several plastics (phthalate-plasticized PVC, polyurethane, polyether-polyamide copolymer and silicone rubber) into olive oil, used as a liquid simulant for fatty foods, was compared with global migration into isooctane, which has been proposed as a new fatty-food simulant. The results showed that the isooctane test (involving contact for 2 hr at 40 degrees C) is not suitable as a substitute for the olive oil test (contact for 10 days at 40 degrees C) for some types of commercial plastic materials.  相似文献   
150.
Circulating prolactin (PRL) levels, dopamine (DA) content, in vitro basal and stimulus-evoked endogenous DA release from arcuate-periventricular nuclei median-eminence fragments were studied in young (4 months) and old (24-25 months) male rats of Sprague-Dawley strain. Serum PRL levels did not differ in young and aged animals. In addition DA tissue content, basal and K+- or d-amphetamine evoked endogenous DA release did not show age-related differences. These results suggest that in male rats of the Sprague-Dawley strain the activity of tuberoinfundibular dopaminergic (TIDA) neurons does not change during senescence, unlike what happens in other strains of rats.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号