全文获取类型
收费全文 | 1699092篇 |
免费 | 136970篇 |
国内免费 | 17671篇 |
专业分类
耳鼻咽喉 | 21142篇 |
儿科学 | 51061篇 |
妇产科学 | 46239篇 |
基础医学 | 235114篇 |
口腔科学 | 42285篇 |
临床医学 | 162181篇 |
内科学 | 333794篇 |
皮肤病学 | 36531篇 |
神经病学 | 135453篇 |
特种医学 | 64253篇 |
外国民族医学 | 559篇 |
外科学 | 244839篇 |
综合类 | 66839篇 |
现状与发展 | 51篇 |
一般理论 | 610篇 |
预防医学 | 129206篇 |
眼科学 | 39329篇 |
药学 | 125612篇 |
165篇 | |
中国医学 | 14145篇 |
肿瘤学 | 104325篇 |
出版年
2022年 | 13456篇 |
2021年 | 23770篇 |
2020年 | 16053篇 |
2019年 | 20684篇 |
2018年 | 26147篇 |
2017年 | 20834篇 |
2016年 | 22116篇 |
2015年 | 27372篇 |
2014年 | 37226篇 |
2013年 | 47993篇 |
2012年 | 67225篇 |
2011年 | 71671篇 |
2010年 | 42369篇 |
2009年 | 38612篇 |
2008年 | 60657篇 |
2007年 | 63403篇 |
2006年 | 63226篇 |
2005年 | 61792篇 |
2004年 | 55538篇 |
2003年 | 52284篇 |
2002年 | 49493篇 |
2001年 | 77887篇 |
2000年 | 79465篇 |
1999年 | 67239篇 |
1998年 | 21036篇 |
1997年 | 19357篇 |
1996年 | 18577篇 |
1995年 | 17588篇 |
1994年 | 15837篇 |
1993年 | 14308篇 |
1992年 | 47806篇 |
1991年 | 45212篇 |
1990年 | 42955篇 |
1989年 | 40822篇 |
1988年 | 37296篇 |
1987年 | 36371篇 |
1986年 | 33674篇 |
1985年 | 31984篇 |
1984年 | 24327篇 |
1983年 | 20435篇 |
1982年 | 12556篇 |
1979年 | 20946篇 |
1978年 | 14763篇 |
1977年 | 12249篇 |
1976年 | 11475篇 |
1975年 | 11723篇 |
1974年 | 14100篇 |
1973年 | 13622篇 |
1972年 | 12711篇 |
1971年 | 11534篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
51.
52.
53.
54.
55.
56.
JM Martín† L Calduch† C Monteagudo‡ I Molina† D Ramón† V Alonso† E Jordᆠ《Journal of the European Academy of Dermatology and Venereology》2006,20(4):428-431
Cutaneous plasmacytosis is a rare disorder characterized by a benign proliferation of mature plasma cells that appears as multiple dark-brown to purplish skin lesions, often associated with polyclonal hypergammaglobulinaemia. We present the case of a 55-year-old Caucasian man who suffered from a cutaneous plasmacytosis associated with two different carcinomas. Cutaneous plasmacytosis seems to be a reactive process because most cases reported are not associated with any apparent underlying disease. Nevertheless, because few reported cases were associated with malignancies, screening of additional neoplasms would be justified. 相似文献
57.
58.
陈晨 《世界核心医学期刊文摘》2006,2(4):47-53
严重脑损伤后17年的社会心理调整;由琥珀酸脱氢酶(SDHA)黄素蛋白(Fp)亚单位突变所致Leigh综合征;动脉瘤性蛛网膜下腔出血早期循环中的内皮细胞激活标记物水平:与脑缺血事件和预后的关系;CSF前列腺素E2水平与认知功能下降和阿尔茨海默病存活率的关系;变异型克罗伊茨费尔特-雅各布病患者的CSF磷酸-tau蛋白浓度升高:诊断和病理学意义。 相似文献
59.
Gazzaruso C. Bruno R. Pujia A. 《世界核心医学期刊文摘》2006,2(8):54-54
背景:针对糖尿病患者Lp(a)水平和冠状动脉疾病(CAD)严重程度之间关系的研究较少并且结论有争议。另外,目前尚无关于apo(a)多态性与上述疾病关系的研究。本研究旨在探讨大样本2型糖尿病患者中冠状动脉粥样硬化的程度与Lp(a)水平及apo(a)多态性的相关性。方法:连续选取227例2型糖 相似文献
60.
Chukwuka C Okafor Hana Haleem-Smith Patrice Laqueriere Paul A Manner Rocky S Tuan 《Journal of orthopaedic research》2006,24(3):461-473
Continual loading and articulation cycles undergone by metallic (e.g., titanium) alloy arthroplasty prostheses lead to liberation of a large number of metallic debris particulates, which have long been implicated as a primary cause of periprosthetic osteolysis and postarthroplasty aseptic implant loosening. Long-term stability of total joint replacement prostheses relies on proper integration between implant biomaterial and osseous tissue, and factors that interfere with this integration are likely to cause osteolysis. Because multipotent mesenchymal stem cells (MSCs) located adjacent to the implant have an osteoprogenitor function and are critical contributors to osseous tissue integrity, when their functions or activities are compromised, osteolysis will most likely occur. To date, it is not certain or sufficiently confirmed whether MSCs endocytose titanium particles, and if so, whether particulate endocytosis has any effect on cellular responses to wear debris. This study seeks to clarify the phenomenon of titanium endocytosis by human MSCs (hMSCs), and investigates the influence of endocytosis on their activities. hMSCs incubated with commercially pure titanium particles exhibited internalized particles, as observed by scanning electron microscopy and confocal laser scanning microscopy, with time-dependent reduction in the number of extracellular particles. Particulate endocytosis was associated with reduced rates of cellular proliferation and cell-substrate adhesion, suppressed osteogenic differentiation, and increased rate of apoptosis. These cellular effects of exposure to titanium particles were reduced when endocytosis was inhibited by treatment with cytochalasin D, and no significant effect was seen when hMSCs were treated only with conditioned medium obtained from particulate-treated cells. These findings strongly suggest that the biological responses of hMSCs to wear debris are triggered primarily by the direct endocytosis of titanium particulates, and not mediated by secreted soluble factors. In this manner, therapeutical approaches that suppress particle endocytosis could reduce the bioreactivity of hMSCs to particulates, and enhance long-term orthopedic implant prognosis by minimizing wear-debris periprosthethic osteolysis. 相似文献