比阿培南致继发性血小板增多症1例报道并碳青霉烯抗生素不良反应文献复习

【】 目的：提高对碳青霉烯抗生素不良反应的认识。方法：报道1例外伤并感染患者使用比阿培南而导致继发性血小板增多症,并且复习碳青霉烯类抗生素不良反应相关文献。结果：停用比阿培南一周后,该患者血小板逐渐降至正常。结论：碳青霉烯类抗生素有可能引起血小板增多症,临床需关注由此可能导致的血管栓塞等不良反应。     

梗塞前心绞痛对急性心肌梗塞近期预后的影响

对１７７例有、无梗塞前心绞痛的首次ＡＭＩ患者进行观察分析，结果为有梗塞前心绞痛组ＣＫ值、住院死亡率、严重心力衰竭和心源性休克发生率明显低于无梗塞前心绞痛组，此仅与梗塞前服用抗心绞痛药物相关。     

pH、HP与消化性溃疡

ｐＨ、ＨＰ与消化性溃疡宋世良（江苏省太仓市第一人民医院太仓２１５４００）ｐＨ是酸碱度的代号。关于酸与溃疡的关系，早在１９１０年Ｓｃｈｗａｒｚ就指出：＂Ｎｏａｃｉｄ，ｎｏｕｌｃｅｒ＂，即＂没有酸就没有溃疡＂。这一医学名言一直沿用了近一个世纪，至今仍有其...     

小儿心脏瓣膜置换术（附2例报告）

２例小儿心脏瓣膜置换术获得成功，其中１例同时施行房间隔缺损和未闭动脉导管缝合术，１例同时施行室间隔缺损补片修补术。作者对该术的指征、手术特点和心肌保护等问题进行了讨论。     

偶测血压正常伴有微量白蛋白尿的2型糖尿病患者动态血压变化

对于伴有微量白蛋白尿的2型糖尿病患者,严格的血压控制对防止糖尿病肾病的进展是非常重要的.临床偶测血压正常的此类患者,24h动态血压监测不一定正常.此类患者应进行降压药物如ACEI治疗以防止糖尿病肾病的发展.为了观察偶测血压正常的伴有微量白蛋白尿的2型糖尿病患者血压变化情况,我们对此类患者血压进行了24h动态监测,报告如下.     

急性心肌梗死致起搏系统故障一例

81岁男性患者,因快慢综合征植入DDD永久型起搏器.术后一月因突发胸闷、气短送我院.     

以视力损害为主要表现的系统性红斑狼疮一例

系统性红斑狼疮(systemic lupus erythematosus，SLE)虽是以多系统、多器官损害伴多种自身抗体为特征的自身免疫性疾病，但在疾病的某一时期．可以某一器官或某一系统受累为突出表现。以视力损害为主要表现的SLE少见，现报道1例如下。     

VEGF-expressing Bone Marrow Mesenchymal Stem Cells Transplantation Improved Heart Function of Myocardial Infarct Rabbits

Objectives To treat myocardial infarction with MSCs transplantation combined with VEGF gene therapy in rabbits and to study its mechanisms. Methods Forty-eight rabbits were randomly divided into MI group (n=12), MSCs group (n=12), VEGF group (n = 12), MSCs VEGF group (M V group, n = 12). Rabbit myocardial infarction models were founded by the ligation of left anterior descending artery. 107 MSCs were injected into the infarct-zone in four sites 2 weeks later in MSCs and M V group. phVEGF gene were injected in infarct-zone in VEGF group and MSCs transfected with phVEGF gene were injected in M V group. Heart function including LVEDP, LVSP, LVDP, -dp/dtmax dp/dtmax, were measured in vivo. The hearts were harvested at 4 weeks after transplantation and sectioned for HE stain, immunohistochemical stain of BrdU andⅧfactor antigen. Results The left ventricular hemodynamics parameters showed that heart function were improved more in M V group than MSCs group, MI group and VEGF group. The numbers of BrdU positive cells in M V group(61±8)were more than in MSCs group (44±8, P < 0.01). The numbers of vessels in infarcted zone were more in M V group (49±8) than in MSCs group (33±6, P < 0.01 ),VEGF group(30±8, P<0.01)and MI group (18±4, P<0.01). Conclusions VEGF- expressing MSCs transplantation could improve heart function after myocardial infarction, and they were more effective than sole MSCs transplantation. Keeping more MSCs survival and ameliorating the blood supply of infarct-zone might be involved in the mechanisms.