Acute pancreatitis associated with duodenal obstruction induced by groove pancreatitis: A case report

RationaleGroove pancreatitis (GP) is a rare form of chronic pancreatitis. Since GP presents with nonspecific symptoms, it can be challenging to diagnose. Duodenal obstruction is often caused by malignant diseases; however, when associated with acute pancreatitis, it is rarely induced by groove pancreatitis.Patient''s concernsA 56-year-old man who presented with acute pancreatitis complained of recurrent upper abdominal discomfort. His concomitant symptoms included abdominal pain, postprandial nausea, and vomiting. Contrast-enhanced computed tomography (CT) of the abdomen showed thickening of the duodenum wall. Gastrointestinal radiographs and upper gastrointestinal endoscopy showed an obstruction of the descending duodenum.DiagnosisThe pathologic diagnosis was groove pancreatitis.InterventionsThe patient underwent gastrojejunostomy to relieve the obstruction.OutcomesThe patient had an uneventful recovery with no complications.LessonsGroove pancreatitis should be considered in the differential diagnosis of patients presenting with acute pancreatitis and duodenal obstruction. These data can help to make a precise diagnosis and develop an appropriate treatment plan.     

66例肝硬变患者的血氧变化

目的:了解肝炎后肝硬变患者的动脉血氧水平并探讨其临床意义。方法:应用自动血气分析仪检测66例肝炎后肝硬变患者和20例正常人的动脉血氧分压、血二氧化碳分压及血氧饱和度。结果:肝硬吏患者的动脉血氧分压为10.55±2.61kPa,明显低于正常人(P<0.05)。低氧血症发生率为56.0％(37/66),与腹水、门静脉增宽、皮肤蜘蛛痣及肝贮备功能降低密切相关,好发于并发急性上消化道出血、肝性脑病,肝肾综合征和自发性腹膜炎的患者。结论:动脉血氧水平检测有助于肝硬变的预后判断。     

海马注射白细胞介素—2对痛阈及甲醛引起的中脑导水管周围灰质和脊 …

AIM: To study the effects of intra-hippocampal injection of interleukin-2 (IL-2) on the substance P-like immunoreactivity (SP-LI) in both periaqueductal gray (PAG) and spinal cord, and on pain threshold in rats. METHODS: Immunohistochemistry technique was used and the paw withdrawal threshold to radiant heat was measured. RESULTS: Microinjection of hIL-2 480 U in hippocampus (Hip) increased the pain threshold (93% +/- 57%, P < 0.01). Injection of formaldehyde (For) in one hindpaw decreased SP-LI neuron number on both sides of PAG (2.9 +/- 2.8 vs 22.1 +/- 0.7, 12.3 +/- 2.0 vs 22.4 +/- 1.0, P < 0.01) and increased SP-LI in ipsilateral spinal cord (0.836 +/- 0.015 vs 0.59 +/- 0.09, P < 0.01). Microinjection of hIL-2 480 U in Hip inhibited the effects of For on the SP-LI on both sides of the PAG (11.3 +/- 2.3 vs 2.9 +/- 2.8, 16.9 +/- 3.4 vs 12.3 +/- 2.0, P < 0.05) and spinal cord (0.71 +/- 0.03 vs 0.836 +/- 0.015, P < 0.01). The combination of intraperitoneal injection of corticotropin and intra-hippocampal injection of IL-2 increased the number of SP-LI neurons in PAG furtherly as compared with IL-2 240 U alone (13.6 +/- 3.6 vs 7.6 +/- 4.3, P < 0.05). CONCLUSION: The analgesic effects of intra-hippocampal injection of IL-2 are mediated, possibly, via the increased of SP in PAG and the decrease of SP in the spinal cord. There is a synergetic relation between IL-2 and corticotropin.     

A rat model for evaluating physiological responses to femoral shaft fracture reduction using a surgical robot

The first step in treatment of displaced femoral shaft fractures is adequate reduction of the fracture fragments. Manually performed, reduction can be challenging, and is frequently associated with soft tissue damage, especially when repeated reduction attempts are made. The magnitude of local and systemic inflammatory responses caused by prolonged and repeated reduction maneuvers has not been fully established. We devised an operative technique utilizing a robotic reduction device for use in a rat. A femoral fracture was simulated by means of an osteotomy. The robot enabled reproduction of both manual and guided precision reductions, performed in a single path movement. An external fixator was designed specifically to manipulate the rat femur and also for fixation of the osteotomy region. First, reduction accuracy was assessed in eight femurs, then the quality of fixator placement and reduction accuracy was analyzed in 22 femurs. In the first case, 100% of the femurs were accurately reduced. In the second case, 91% had successful stable fixation and an accurate reduction was achieved in 86% of the specimens. We demonstrated the feasibility of a model of robot‐assisted fracture reduction that could be used to analyze the effects of reduction on the surrounding soft tissue via biochemical and histopathological means. A future aspect will be to evaluate whether the robot confers an advantage in fracture reduction versus the conventional technique, which would have significant implications for the use of robotic devices in orthopaedic surgery. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res     

桡骨远端骨折类型与内外固定植入体、人工假体及其骨替代物的关系★

学术背景：随着桡骨远端骨折三柱理论的提出，以及各种固定材料不断的出现，桡骨远端骨折治疗中应用内外固定植入体、人工假体、骨替代物的相关研究已成为热点。 目的：通过对各种植入体、植入材料的比较选择，进一步认识如何用最简单、最安全的方法处理桡骨远端骨折，使每一位患者、每一种骨折类型能够达到微创、解剖复位、相对稳定的最佳效果。 检索策略：应用计算机检索PubMed 1990-01/2006-12相关的文献，检索词“distal radius，fracture，treatment”，限定文献语言种类为English。检索到临床观察及基础研究文章882篇，综述类文章159篇。对资料进行初审，纳入文献标准为与桡骨远端骨折治疗上相关的临床观察及基础研究文章169篇，选取针对性强的文章，同一领域的文献则选择近期发表或权威杂志的文章。排除非相关文献及综述872篇。未发表的文献均未列入统计。 文献评价：对所得文献进行提炼，按上述标准纳入31篇。 资料综合：①石膏、夹板外固定曾经一直是桡骨远端骨折治疗的标准方法。②近年来，随着腕部生物力学及显微解剖学的发展，以及对桡骨远端骨折复位与重建要求的提高，桡骨远端骨折的治疗观念不断更新，不同类型的桡骨远端骨折出现了不同的治疗方法。③经皮穿针复位内固定植入体主要适用于关节外骨折。④外固定支架是治疗桡骨远端骨折的有效方法之一，尤其是桡骨短缩畸形可以通过外固定支架得到矫正。⑤桡骨远端骨折切开复位内固定置入技术的发展主要是由内固定材料设计上的改进及手术入路的选择所引起的。⑥人工腕关节逐渐被应用于临床，为因腕关节严重创伤、关节僵硬和严重创伤性关节炎的患者提供了一个可供选择的新方法。⑦桡骨远端骨折常存在干骺端骨缺损，尤其是老年骨质疏松明显的患者，治疗时常需要进行骨或骨替代物移植，可注射的磷酸钙骨水泥是治疗桡骨远端骨折的一个新选择。 结论：任何一种单独的方法都不能处理全部的桡骨远端骨折，对每一位患者、每一种骨折类型，应制定个体化的治疗方案，选择适合的植入物及植入材料，采用多种联合的治疗方法。     

项目干预对已婚男性生殖健康知识及服务需求影响的研究

目的 研究干预对已婚男性生殖健康知识及服务需求的影响.方法 采用分层-整群抽样的方法选取仪征市302名已婚男性,对他们进行了问卷调查.经过3年的项目干预,采用相同的调查问卷对他们进行了终点调查.结果 干预前后生殖健康知识和个人行为习惯显著提高,对男性生殖健康知识和服务的需求依然强烈.结论 干预活动对已婚男性生殖健康知识的普及有明显的作用,需要通过多种途径提供为男性提供生殖健康知识和服务,指导男性建立科学的生活方式.     

通用引物PCR同时检测胎儿组织中4种疱疹病毒

目的：介绍一种敏感特异简便快速同时检测４种疱疹病毒的通用引物ＰＣＲ，用于临床检测和流行病学研究。方法：根据它们的高度同源序列－ＤＮＡ聚合酶基因序列设计至引物能同时扩增这４种病毒，根据它们扩增片断的大小就可将它们区分，无需再用内切酶消化。结果：总的阳性率：ＣＭＶ＝２０．１８％，ＨＳＶ＝１４．０７％，ＥＢＶ＝１．４８％。结论：１．本研究建立的通用引物ＰＣＲ是一种敏感特异简便快速能同时检测４种疱疹病毒的     

Intervertebral disc transplantation: a biological approach to motion preservation

Intervertebral disc transplantation was developed in a bipedal animal model through the stages of autograft, fresh allograft and fresh frozen allograft. Results showed that the allografts were able to survive through a deep freezing protocol and maintain cell viability after transplantation without significant immunoreaction. Although degeneration of the allograft appeared to be inevitable, it was able to maintain stability and mobility of the functional spinal unit. These findings were similarly reproduced in the human clinical trial with excellent mid-term clinical results at 5 years. The process of evolution and findings were summarized in this review.

     

Model TJ-IV Computer-Assisted Vectorcardiogram Analysis System

During the last1 6years,we have successfullydeveloped the computer- assisted vectorcardiogramanalysis systems:model TJ- , , .Due to thetechnical limitations at the times,some problems re-mained with the previous versions,such asthe recog-nition accuracy for vectorcardiograms,the measure-ment of trough and peak point of complex QRS,thecalculation of the ratio of T loop length to its width,and the area of spatial vectors etc.In this study,wedeveloped a new version of the computer- assisted ve…