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321.
胶原酶在治疗烧、创伤创面中应用的临床观察 总被引:2,自引:0,他引:2
目的 探讨胶原酶制剂治疗烧、创伤创面的临床疗效。方法 创面常规清创后涂胶原酶制剂外敷凡士林纱布或无菌纱布包扎 ,每日或隔日换药。结果 本组 2 2 0例 ,其中 4 4例浅Ⅱ度烧伤创面用药后 8~ 11d基本愈合 ,83例深Ⅱ度创面 12~ 18d愈合 ,4 2例Ⅲ度创面用药 7~ 10d基本达到植皮条件 ,5 1例创伤所致肌腱、韧带、骨骼等外露创面用药 12~ 19d基本具备植皮条件。结论 胶原酶治疗烧、创伤创面 ,具有加速坏死组织液化、促进损伤部位残留表皮细胞生长、利于创面修复和减轻瘢痕的作用 相似文献
322.
NADPH-Diaphorase-Positive Neurons in Primate Cerebral Cortex Colocalize with GABA and Calcium-Binding Proteins 总被引:3,自引:3,他引:0
Neurons in the monkey cerebral cortex containing nicotinamideadenine dinucleotide phosphate-diaphorase (NADPH-d) can he dividedinto two distinct types, both nonpyramidal. Type I neurons havea large soma (diameter 2050 µm), a dense NADPH-dhistochemical reaction. and are distributed throughout the cortex,but mainly in the subcortical white matter, and are mostly aspiny.Type II cells have a small soma (< 20 µm) with lightNADPH-d reactivity and are distributed primarily in the supragranularlayers, particularly layers II and upper III. The numericaldensity of type II cells is much greater than that of type I.Type I neurons also stain for GABA and a few intracortical typeI cells contain calbindin. All type II cells found here arecolocalized with both GABA and calbindin. Neither type I nortype II cells are stained for parvalbumin. Together with previous observations that almost all corticalNADPH-d cells in various subprimates are like type I cells,we suggest that type II cells may form a group of NADPH-d-richneurons differentiated in higher mammalian cortex from a subpopulationof calbindin-containing GABAergic interneurons, and these nitricoxide-synthesizing cells may play a role in control of intracorticalneuronal activity characteristic of higher cerebral functionsin advanced mammals. 相似文献
323.
324.
预移植在胚胎移植中的意义 总被引:2,自引:0,他引:2
目的 :评价预移植在胚胎移植中的作用。 方法 :在超声波引导下胚胎移植 114个周期 ,其中 10 1个周期进行预移植。比较预移植与未预移植周期临床妊娠率和胚胎种植率 ;按预移植与实际胚胎放置深度差值分组 ,并比较两组妊娠率和胚胎种植率。 结果 :预移植周期与未预移植周期临床妊娠率和种植率统计学差异无显著性(5 9.4 1%和 6 1.5 4 % ,35 .81%和 31.4 3% ,P均 >0 .0 5 ) ;按预移植与实际胚胎放置深度差值分组后 ,两组妊娠率和种植率统计学差异也无显著性 (6 1.5 4 %和 5 8.6 7% ,4 0 .79%和 34.0 9% ,P均 >0 .0 5 )。 结论 :在胚胎移植技术中 ,预移植不能准确指引胚胎移植深度 相似文献
325.
Recapitulation of fast skeletal muscle development in zebrafish by transgenic expression of GFP under the mylz2 promoter. 总被引:1,自引:0,他引:1
Bensheng Ju Shang Wei Chong Jiangyan He Xukun Wang Yanfei Xu Haiyan Wan Yan Tong Tie Yan Vladimir Korzh Zhiyuan Gong 《Developmental dynamics》2003,227(1):14-26
A 1,934-bp muscle-specific promoter from the zebrafish mylz2 gene was isolated and characterized by transgenic analysis. By using a series of 5' promoter deletions linked to the green fluorescent protein (gfp) reporter gene, transient transgenic analysis indicated that the strength of promoter activity appeared to correlate to the number of muscle cis-elements in the promoter and that a minimal -77-bp region was sufficient for a relatively strong promoter activity in muscle cells. Stable transgenic lines were obtained from several mylz2-gfp constructs. GFP expression in the 1,934-bp promoter transgenic lines mimicked well the expression pattern of endogenous mylz2 mRNA in both somitic muscle and nonsomitic muscles, including fin, eye, jaw, and gill muscles. An identical pattern of GFP expression, although at a much lower level, was observed from a transgenic line with a shorter 871-bp promoter. Our observation indicates that there is no distinct cis-element for activation of mylz2 in different skeletal muscles. Furthermore, RNA encoding a dominant negative form of cAMP-dependent protein kinase A was injected into mylz2-gfp transgenic embryos and GFP expression was significantly reduced due to an expanded slow muscle development at the expense of GFP-expressing fast muscle. The mylz2-gfp transgene was also transferred into two zebrafish mutants, spadetail and chordino, and several novel phenotypes in muscle development in these mutants were discovered. 相似文献
326.
Zheng Qi-xin Zhu Tong-bai Du Jing-yuan Hong Guang-xiang Li Shi-pu Yan Yun-hua Zhang En-dang 《华中科技大学学报(医学英德文版)》1992,12(3):173-178
Summary The authors have prepared the artificial bone of porous tricalcium phosphate ceramics according to an appropriate formula
and manufacturing technology. Physical and chemical testing shows that it possesses several distinguishing features: the communicating
pores and macro/micropores; mean pore size, 380 μm (from 240 μm to 510 μm); porosity, 46.4 %; and compressive strength, 97.4
kg/cm2. It consists of CaO (49.09 %) and P2O5 (48.84 %). The testing of its biocompatibility shows that it is devoid of systemic or local toxicity, and free of irritation
or foreign body response in tissues, and it does not result in hemolysis or mutation. The new bone readily grows into its
pores with direct contact to the implanted material. 11 cases of bone defects were treated with this artificial bone with
satisfactory results. 相似文献
327.
我国登革2型病毒43株包膜E蛋白基因的特征 总被引:2,自引:0,他引:2
对我国1987年流行的登革2型病毒43株包膜E蛋白基因的核苷酸序列进行了分析。结果表明登革2型病毒43株包膜E蛋白基因核苷酸序列含1485个核苷酸,编码495个氨基酸,并就其核苷酸序列及其相应的氨基酸序列与其它的登革2型病毒株进行了比较,发现核苷酸序列与我国1985年分离的登革2型病毒04株,新几内亚C株(NGC),牙买加株1409(JAM)和马来西亚当地流行株M1(登革出血热)、血2(登革休克综合征)、M3(登革热)同源性分别是95.8%、94.6%、97.5%、925%、92.7%和939%,氨基酸序列的同源性分别是94.3%、94.3%、96.0%、93.7%、93.7%和91.5%,推断出的氨基酸序列显示出12个保守的半胱氨酸残基和两个潜在的糖基化位点,分别位于Asn-67和Asn-153位。 相似文献
328.
329.
五型病毒性肝炎的暴露因素与临床表现的比较 总被引:2,自引:1,他引:1
比较急性病毒性肝炎患者感染打危险因素,同时比较五型肝炎的症状和体征。连续收集急性病毒性肝炎患者血清293份,用ELISA法检测了五型肝炎病毒的病原学指标,并进行了流赞美同学调查。暴露因素:丙肝的肠道外暴露外明显多于甲肝;甲肝和戊肝有较高的“甲肝”患者接触史;乙肝,丙肝和丁肝有高的“乙肝”接触史,与甲肝,戊肝相比差异显著。 相似文献
330.
The subdivisions of the sacral intermediolateral nucleus (IML) of the cat have been studied by using a double-labeling technique of retrograde Fluoro-gold (FG) and wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) tracing. The parasympathetic preganglionic neurons (PGNs) that were labeled by the FG injected into the pelvic nerve formed a ‘V’-shaped column known as the sacral parasympathetic nucleus (SPN) in the sacral IML. The neurons that were labeled by the WGA-HRP applied to the lateral parabrachial nucleus (PBL) formed an elongated spindle-shaped column extending throughout the IML of the sacral segments. We designated it by the name of sacral visceral sensory nucleus (SVSN). These findings indicate that the sacral IML of the cat contain two distinct subdivisions, SPN and SVSN. 相似文献