全文获取类型
收费全文 | 14099篇 |
免费 | 706篇 |
国内免费 | 93篇 |
专业分类
耳鼻咽喉 | 153篇 |
儿科学 | 258篇 |
妇产科学 | 74篇 |
基础医学 | 1518篇 |
口腔科学 | 469篇 |
临床医学 | 911篇 |
内科学 | 3614篇 |
皮肤病学 | 403篇 |
神经病学 | 896篇 |
特种医学 | 554篇 |
外科学 | 2329篇 |
综合类 | 52篇 |
预防医学 | 436篇 |
眼科学 | 383篇 |
药学 | 1345篇 |
中国医学 | 18篇 |
肿瘤学 | 1485篇 |
出版年
2023年 | 92篇 |
2022年 | 195篇 |
2021年 | 326篇 |
2020年 | 192篇 |
2019年 | 251篇 |
2018年 | 343篇 |
2017年 | 254篇 |
2016年 | 295篇 |
2015年 | 295篇 |
2014年 | 382篇 |
2013年 | 492篇 |
2012年 | 773篇 |
2011年 | 839篇 |
2010年 | 514篇 |
2009年 | 407篇 |
2008年 | 738篇 |
2007年 | 792篇 |
2006年 | 807篇 |
2005年 | 776篇 |
2004年 | 711篇 |
2003年 | 685篇 |
2002年 | 697篇 |
2001年 | 334篇 |
2000年 | 379篇 |
1999年 | 349篇 |
1998年 | 148篇 |
1997年 | 128篇 |
1996年 | 124篇 |
1995年 | 102篇 |
1994年 | 84篇 |
1993年 | 79篇 |
1992年 | 211篇 |
1991年 | 178篇 |
1990年 | 181篇 |
1989年 | 191篇 |
1988年 | 171篇 |
1987年 | 161篇 |
1986年 | 136篇 |
1985年 | 148篇 |
1984年 | 120篇 |
1983年 | 85篇 |
1982年 | 44篇 |
1981年 | 53篇 |
1979年 | 65篇 |
1978年 | 46篇 |
1977年 | 45篇 |
1973年 | 51篇 |
1971年 | 42篇 |
1969年 | 50篇 |
1968年 | 52篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
M Usui T Kimura J Yamazaki 《The Journal of bone and joint surgery. American volume》1990,72(9):1370-1373
We successfully replanted five amputated legs in five patients and followed the patients for two years or more (average, six years and three months). Although some patients found it impossible to squat and to run because of joint contractures, muscle weakness, or deformities of the foot, all patients could perform other activities without difficulty. None had important pain or any intolerance to cold, and all were satisfied with the results of the replantation. 相似文献
12.
Lipoprotein [a] (Lp[a]) is known to show high values in patients with ischemic heart disease (IHD). In the present study attempts were made to determine Lp[a] levels and to investigate the association of Lp[a] and other atherosclerotic risk factors in patients with chronic renal failure treated by hemodialysis. Lp[a] concentrations were measured in 30 hemodialysis patients in the age range 34 to 77 years. Mean (+/- SD) levels of serum Lp[a] were not elevated in the hemodialysis patients compared to controls (19.3 +/- 18.0 mg/dl vs. 18.3 +/- 10.4 mg/dl, respectively). We found no statistically significant correlation of Lp[a] with either cholesterol, triglycerides, HDL-C or apoproteins. However, compared with controls, more than fivefold as many of those hemodialysis patients had high risk (greater than 30 mg/dl) concentrations of Lp[a]. Lp[a] tended to increase in hemodialysis patients with diabetes mellitus and/or ischemic heart disease. In patients with high levels of Lp[a] (greater than 30 mg/dl), Lp[a] tended to correlate positively with cholesterol, LDL-, HDL-C, apo B or apo B/AI. Incidence of IHD was also elevated in these patients. Along with other known risk factors such as hyperlipidemia and hypertension, an increased concentration of Lp[a] may play an important role in accelerating development of atherosclerosis in this condition. 相似文献
13.
14.
15.
16.
17.
Toshihiko Imakiire Yuichi Kikuchi Muneharu Yamada Taketoshi Kushiyama Keishi Higashi Naomi Hyodo Kojiro Yamamoto Takashi Oda Shigenobu Suzuki Soichiro Miura 《Hypertension research》2007,30(7):635-642
The mechanisms of hypertensive nephrosclerosis are not fully understood. In experimental models of the disease, inflammatory reactions such as macrophage infiltration play an important role. In human hypertensive nephrosclerosis, however, there have been few studies examining the role of inflammation histologically. We investigated whether the number of infiltrating macrophages was increased in human hypertensive nephrosclerosis, and evaluated the effects of a blockade of the renin-angiotensin system on clinical and histological findings. We examined macrophage infiltration using immunohistochemistry in renal biopsy specimens obtained from 16 patients with hypertensive nephrosclerosis, 5 patients with IgA nephropathy, 5 patients with membranous nephropathy, and 5 patients with minimal change nephrotic syndrome. The number of infiltrating macrophages in glomeruli was significantly larger in the patients with hypertensive nephrosclerosis than in those with minimal change nephrotic syndrome. The patients with hypertensive nephrosclerosis were divided into groups based on their use of antihypertensive agents at the time of renal biopsy. We investigated the effects of antihypertensive agents on clinical findings, macrophage infiltration, and monocyte chemoattractant protein-1 expression. There was no difference in clinical findings between the hypertensive groups. The numbers of infiltrating macrophages and monocyte chemoattractant protein-1-positive cells in glomeruli were significantly smaller in patients treated with an angiotensin-converting enzyme inhibitor or angiotensin II type 1 receptor blocker, whereas calcium channel blockers had no influence on histological findings. In conclusion, inflammation is involved in the progression of human hypertensive nephrosclerosis and the inflammatory process is inhibited by blocking the renin-angiotensin system. 相似文献
18.
Kaname Ishii Yuichi Hayashida Katsuhiro Yoshimoto Hidehiro Tajima Uichiro Fuchisaki Toshiya Takeda Toru Kamata Hirotoshi Miyamori Masahiro Kanno 《Nihon Shokakibyo Gakkai zasshi》2006,103(8):931-935
We report a case of granulocyte-colony stimulating factor producing gastric cancer with multiple liver metastases. A 68-year-old woman who complained of epigastralgia visited our hospital. Upper gastrointestinal endoscopic examination revealed a type-2 gastric cancer. The laboratory data at admission indicated leukocytosis (35,900/microl) and a high level of serum granulocyte-colony stimulating factor (61 pg/mg). Granulocyte-colony stimulating factor producing gastric cancer was diagnosed by immunohistochemistry of biopsy specimen. Since we detected multiple liver metastases, chemotherapy was performed. Granulocyte-colony stimulating factor-producing gastric cancer is relatively rare and we summarize previous reports. 相似文献
19.
Kenji Tsukada Shigeru Kobayashi Tatsuya Gotoh Naoki Asakage Masayuki Sekine Morio Sasaki Eiji Miyazaki Takahisa Suzuki Toshio Yamada Shu Hirai Shigetaka Yamazaki 《Digestive endoscopy》2006,18(1):55-58
A case of early gastric carcinoma accompanied by Dieulafoy ulcer is presented. The patient, a 26‐year‐old female, visited our emergency room with chief complaints of massive hematemesis and tarry stool. The initial endoscopic examination revealed a superficial depressed lesion with a faded color accompanied by a tiny ulcer with converging folds at the anterior wall of the middle gastric body. Although no active bleeding vessel was found at that time, the patient was admitted to our hospital for further check‐ups and treatment. On the 6th hospital day, she developed massive hematemesis resulting in shock. Urgent endoscopy, this time, disclosed an exposed bleeding vessel at the small ulcer floor previously mentioned, and endoscopic hemostasis was achieved. Since, however, a biopsy at initial examination from the surrounding depressed area proved carcinoma, a partial distal gastrectomy was subsequently carried out. Histological examination of the resected specimen confirmed the diagnosis of carcinoma limited to the mucosa and submucosa along with findings consistent with Dieulafoy ulcer. This is a rare case of combination of early cancer and Dieulafoy ulcer particularly in such a young patient. A review of the literature is also presented. 相似文献
20.
Satoru Miyawaki Ryuichi Yamazaki Takehiko Harada Shigehiko Takanashi Tadashi Nagashima Hiroshi Nakaguchi Ryo Okazaki Kazuhito Yamazaki Yasuo Ishida Akira Matsuno 《Journal of clinical neuroscience》2007,14(5):481-484
Skull metastasis of thyroid carcinoma is rare. The majority of skull metastases of thyroid carcinoma are of the follicular subtype, rather than thyroid papillary carcinoma. In this report, a 55-year-old woman with skull metastasis from thyroid papillary carcinoma is presented. The metastatic lesion of the skull was hypervascular and osteolytic, and the bleeding was profuse during resection. There have been only four reports of skull metastasis from thyroid papillary carcinoma. The mean period from the initial diagnosis of thyroid carcinoma until the detection of skull metastasis is 23.3 years, whereas in this patient, it was about 2 years. Therefore, in the clinical course of thyroid papillary carcinoma, skull metastasis should be considered, and the patient should be meticulously followed up. 相似文献