青少年骨性Ⅰ类错 畸形拔牙矫治前后面部软组织三维特征变化研究

目的应用3dMD^?面部三维成像系统研究拔牙矫治对青少年骨性Ⅰ类错 畸形面部软组织三维特征的影响,为正畸矫治提供参考。 方法选取2016—2019年期间于中山大学附属口腔医院正畸科就诊的青少年骨性Ⅰ类患者50例,其中拔牙组25例,非拔牙组25例为对照组,应用3dMD^?收集正畸治疗前后的面部三维图像数据,通过3dMD^? vultus软件测量线距、角度、体积变化,应用SPSS 20.0统计分析软件对各项测量指标的比较采用独立样本t检验。 结果正畸治疗后,在线距方面,拔牙组、非拔牙组前下面高变化量分别为（0.28 ± 2.28）、（1.85 ± 2.18）mm,差异有统计学意义（t = -2.238,P = 0.031）;拔牙组下颌高、颏高、唇宽变化量分别为（-0.52 ± 2.31）、（-1.14 ± 2.64）、（-1.33 ± 3.62）mm,非拔牙组则分别为（1.64 ± 2.42）、（0.93 ± 2.51）、（1.40 ± 2.16）mm,差异有统计学意义（t_下颌高 = -2.878,P_下颌高 = 0.007;t_颏高 = -2.506,P_颏高 = 0.017;t_唇宽 = -2.942,P_唇宽 = 0.006）。在角度方面,拔牙组、非拔牙组鼻唇角变化量分别为4.91° ± 3.12°、1.50° ± 4.26°,差异有统计学意义（t = 2.692,P = 0.011）;拔牙组、非拔牙组颏唇角变化量分别为-0.24° ± 6.83°、4.82° ± 6.50°,差异有统计学意义（t = -2.373,P = 0.023）;拔牙组、非拔牙组唇角变化量分别为-16.80° ± 12.65°、-1.04° ± 11.24°,差异有统计学意义（t = -4.171,P<0.001）。在体积方面,拔牙组、非拔牙组唇部变化量分别为（-0.66 ± 1.24）、（0.46 ± 1.43）cm³,差异有统计学意义（t = -2.584,P = 0.014）;拔牙组、非拔牙组颏部变化量分别为（-0.16 ± 0.94）、（0.65 ± 0.91）cm³,差异有统计学意义（t = -2.766,P = 0.009）。 结论（1）拔牙与非拔牙矫治对患者面下1/3水平向无明显影响,但对面下1/3的垂直向影响有差异,非拔牙较拔牙矫治更易导致面部高度的增加;（2）开唇露齿的青少年患者经拔牙矫治可有效改善颏、唇部形态;（3）对于面部消瘦、颧部凸出的患者,应慎重拔牙矫治。     

Diagnostic value of echocardiography in paracardiac cystic lesions: 43 cases from one single medical center

The International Journal of Cardiovascular Imaging - Paracardial cystic lesions (PCLs) are rare, benign lesions and may occur in any part surrounding the heart. It covers a variety of pathological...     

Three-dimensionally ordered macro–mesoporous CoMo bulk catalysts with superior performance in hydrodesulfurization of thiophene

The introduction of surfactants during the fabrication of hydrodesulfurization catalysts could not only tune the microstructure but also promote the dispersion of active components. In this work, CoMo bulk catalysts with the hierarchical structure of three-dimensionally ordered macro–mesopores were successfully fabricated by using a colloidal crystal template with the addition of PEG 400 and/or F127 surfactants. The obtained samples were characterized by various techniques, and the possible mechanism of the structure formation was also discussed. The characterization and evaluation results reveal that the addition of surfactants can promote the formation of the mesopores (3–4 nm) inside the macroporous walls of these bulk catalysts, which is essential for the increase of catalyst surface area, and the active sites for reaction. The CoMo–PF-1 catalyst displayed superior catalytic performance for thiophene hydrodesulfurization with the thiophene conversion of 99.4% under 1 MPa at 360 °C, which is much higher than that (77.8%) at 0.1 MPa. This result is even comparable to our previous report with the thiophene conversion of 99.2% over the 3DOM CoMo catalyst under 3 MPa.

The addition of surfactants can promote the formation of mesopores and improve the dispersion of MoS₂ slabs.     

Amino group dependent sensing properties of metal–organic frameworks: selective turn-on fluorescence detection of lysine and arginine

Recently, metal–organic frameworks (MOFs) have been extensively investigated as fluorescence chemsensors due to their tunable porosity, framework structure and photoluminescence properties. In this paper, a well-known Zr(iv)-based MOF, UiO-66-NH₂ was demonstrated to have capability for detection of l-lysine (Lys) and l-arginine (Arg) selectively from common essential amino acids in aqueous media via a fluorescence turn-on mechanism. Further investigation reveals its high sensitivity and strong anti-interference properties. Moreover, the possible mechanism for sensing Lys and Arg was explored by FT-IR and ¹H-NMR, and the results indicate that the enhancement of the fluorescence could be ascribed to the adsorption of Lys/Arg and the hydrogen bonding interactions between Lys/Arg and the amino group of UiO-66-NH₂. The difference of the sensing capacity and sensitivity between UiO-66 and UiO-66-NH₂ revealed that the amino group plays an essential role in the sensing performance. This work presents a unique example of the functional group dependent sensing properties of MOFs.

The amino group of UiO-66-NH₂ was demonstrated to play an important role in selective fluorescence turn-on sensing of lysine and arginine.     

64排128层螺旋CT冠状动脉CTA在冠心病筛查中的临床应用

目的:探讨64排128层螺旋CT冠状动脉血管造影术(CTA)在冠心病筛查中的临床应用。方法:回顾性分析2018年6月~2019年10月某院收治的70例冠心病患者临床资料,均采用64排128层螺旋CT冠状动脉CTA检查,1周内进行选择性冠脉造影(CAG)检查。以CAG诊断为金标准,记录CT影像表现,统计冠状动脉狭窄情况;以CAG检查为金标准,分析64排128层螺旋CT冠状动脉CTA对冠脉狭窄诊断的敏感性、特异性。结果:70例患者经64排128层螺旋CT冠状动脉CTA检查,以CAG检查为金标准,螺旋CTA图像表现为冠状动脉轻度狭窄44支,中度54支,重度40支,正常105支;CAG检查冠状动脉轻度狭窄39支,中度62支,重度46支,正常106支。螺旋CTA图像显示轻度冠状动脉狭窄数量多于CAG检查数量,中度、重度狭窄少于CAG检查;64排128层螺旋CT冠状动脉CTA检查敏感性为87.18%,特异性为97.06%。结论:冠心病采用64排128层螺旋CT冠状动脉CTA筛查,具有较高的敏感性、特异性,为冠心病临床筛查、诊断提供参考依据,值得临床推广应用。     

宫颈癌后装放疗时膀胱直肠小肠受照剂量探讨

目的 探讨宫颈癌腔内放疗时不同体积的膀胱、直肠与危及器官受照剂量的关系。方法 选取宫颈癌患者共47例,给予剂量点处方剂量600 cGy的高剂量率腔内后装治疗,用剂量体积直方图(DVH)评价标准计划下不同体积的膀胱、直肠和小肠对相应受照剂量的影响。将膀胱按体积大小分成<80 cm³组、80~120 cm³组和>120 cm³组,直肠按体积大小分成>60 cm³ 组和≤60 cm³组,分析其体积与剂量分布的关系。采用方差分析和t检验方法分析D_{1 cm³}、D_{2 cm³}、D_30%和D_50%。结果 与膀胱体积<80 cm³组相比,80~120 cm³组和>120 cm³组的膀胱D_30%、D_50%受照剂量增高(F=5.074、5.088,P<0.05),小肠D_{1 cm³}和D_{2 cm³}值差异无统计学意义(P>0.05);与直肠体积>60 cm³ 组相比,≤60 cm³组的直肠D_{1 cm³}受照剂量减小(t=-2.045,P<0.05)。结论 宫颈癌近距离放疗时,保持膀胱的适当充盈,直肠体积的减少,可使直肠、膀胱和小肠的受照射剂量均相对降低,从而减少放疗的不良反应。     

科素亚联合血塞通软胶囊治疗胡桃夹综合征38例的疗效观察

目的探讨科素亚联合血塞通软胶囊治疗胡桃夹综合征(NCS)的临床疗效。方法回顾性对照分析我科2008年6-月—2014年3月经超声检查确诊的38例NCS患者,应用科素亚联合血塞通软胶囊治疗前及治疗3个月后的临床资料,并进行统计学比较。结果经过3个月的药物治疗,NCS患者的蛋白尿、血尿症状、左肾静脉内径及血流参数指标较治疗前均有明显好转。结论科素亚联合血塞通软胶囊治疗NCS疗效显著。