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51.
52.
Jung Soo Park Hyo Sung Kwak Jong Myong Lee Eun Jeong Koh Gyung Ho Chung Seung Bae Hwang 《Journal of Korean Neurosurgical Society》2015,57(2):94-99
Objective
The purpose of our study was to assess prevalence of carotid intraplaque hemorrhage (IPH) and associations between territorial acute infarction and IPH on magnetization-prepared rapid acquisition with gradient-echo (MPRAGE) in patients with acute neurologic symptoms.Methods
83 patients with suspected acute neurologic symptoms were evaluated with both brain diffusion weighted imaging (DWI) and carotid MPRAGE sequences. Carotid plaque with high signal intensity on MPRAGE of >200% that of adjacent muscle was categorized as IPH. We analyzed the prevalence of IPH and its correlation with territorial acute infarction.Results
Of 166 arteries, 39 had a carotid artery plaque. Of these arteries, 26 had carotid artery stenosis less than 50%. In all carotid arteries, MR-depicted IPH was found in 7.2% (12/166). High-signal intensity on DWI was found in 17.5% (29/166). Combined lesion with ipsilateral high-signal intensity on DWI and IPH on carotid MPRAGE sequence was found in 6 lesions (6/166, 3.6%). Of patients with carotid artery plaque, MR-predicted IPH was found in 30.8% (12/39) and match lesions with high-signal intensity on DWI and MPRAGE was found in 15.4% (6/39). MR-predicted IPH was significantly higher prevalence in high-grade stenosis group (p=0.010). Relative risk between carotid MPRAGE-positive signal and ipsilateral high-signal intensity on DWI in arteries with carotid artery plaques was 6.8 (p=0.010).Conclusion
Carotid MPRAGE-positive signal in patients was associated with an increased risk of territorial acute infarction as detected objectively by brain DWI. The relative risk of stroke was increased in high-grade stenosis categories. 相似文献53.
Telomere length changes in patients with aplastic anaemia 总被引:5,自引:0,他引:5
Lee JJ Kook H Chung IJ Na JA Park MR Hwang TJ Kwak JY Sohn SK Kim HJ 《British journal of haematology》2001,112(4):1025-1030
To investigate telomere changes in patients with aplastic anaemia (AA) and clinical factors influencing the telomere dynamics, telomere length (TL) was measured in peripheral blood mononuclear cells using Southern blot analysis of 42 patients with AA and 39 healthy normal controls. Nineteen patients received supportive treatment only, while the remaining 23 patients received immunosuppressive therapy with anti-thymocyte globulin or anti-lymphocyte globulin +/- cyclosporin A. In AA patients, TL was on average 1.41 kb shorter than that of age-matched normal controls (P < 0.001). In patients treated with immunosuppression, the mean TL of non-responders was significantly shorter than that of age-matched normal controls (P < 0.001), while no difference in TL was detected in responders compared with controls. Positive correlation was observed between the extent of telomere shortening, the severity of neutropenia (P = 0.05) and the degree of mean corpuscular volume elevation (P = 0.005) at the time of the study. However, there was no correlation with time elapsed since diagnosis (P = 0.214). These findings suggest that haematopoietic stem cells in patients with AA rapidly lose TL at the onset of the disease. The TL shortening may reflect the severity of impairment of haematopoiesis. 相似文献
54.
Byoung-Sun Park Ju-Hyun Kim Mee-Young Kim Lim-Kyu Lee Seung-Min Yang Hye-Joo Jeon Won-Deok Lee Ji-Woong Noh Jeong-Uk Lee Taek-Yong Kwak Tae-Hyun Lee Ju-Young Kim Junghwan Kim 《Journal of Physical Therapy Science》2015,27(3):641-644
[Purpose] The purpose of this study was to investigate the effects of strengthening
exercises for the hip extensors on the gait performance and stability of patients with
hemiplegia. [Subjects and Methods] The subjects were fifteen stroke patients (ten males,
five females). The experimental subjects performed a hip extensor strengthening exercise
(HESE) program for a total of four weeks. [Results] The experimental subjects showed
significant improvements after the HESE program. Especially, walking speed and the
affected side stance phase time significantly increased after the HESE program.
Furthermore, the affected side stride length and symmetry index in the stance phase
significantly increased after HESE program. [Conclusion] These results suggest that the
HESE program may, in part, help to improve gait performance ability and stabilize physical
disability after stroke.Key words: Stroke patients, Hip extensor strengthening exercise (HESE) program, Gait function 相似文献
55.
Byoung-Sun Park Mee-Young Kim Lim-Kyu Lee Seung-Min Yang Won-Deok Lee Ji-Woong Noh Yong-Sub Shin Ju-Hyun Kim Jeong-Uk Lee Taek-Yong Kwak Tae-Hyun Lee Ju-Young Kim Junghwan Kim 《Journal of Physical Therapy Science》2015,27(5):1603-1607
[Purpose] The purpose of this study was to confirm the effects of both conventional
overground gait training (CGT) and a gait trainer with partial body weight support (GTBWS)
on spatiotemporal gait parameters of patients with hemiparesis following chronic stroke.
[Subjects and Methods] Thirty stroke patients were alternately assigned to one of two
treatment groups, and both groups underwent CGT and GTBWS. [Results] The functional
ambulation classification on the affected side improved significantly in the CGT and GTBWS
groups. Walking speed also improved significantly in both groups. [Conclusion] These
results suggest that the GTBWS in company with CGT may be, in part, an effective method of
gait training for restoring gait ability in patients after a stroke.Key words: Gait training, Spatiotemporal gait parameters, Stroke patients 相似文献
56.
57.
58.
Hong Suk Kwak Jeong Joon Yoo Young-Kyun Lee Kyung-Hoi Koo Kang Sup Yoon Hee Joong Kim 《Clinics in Orthopedic Surgery》2015,7(1):46-53
BackgroundWear cannot be completely prevented after total hip arthroplasty. If severe polyethylene (PE) liner wear develops, the so-called catastrophic failure occurs and metallosis develops. We postulated that longevity of the new implant may be affected after revision surgery for metallosis following a catastrophic failure of a PE liner due to the substantial amount of PE wear particles and infiltration of the metal particles in this catastrophic condition.MethodsTwenty-three hips of 23 patients were identified because they showed metallosis during revision total hip arthroplasties performed in Seoul National University Hospital between January 1996 and August 2004. They were followed for at least 6.5 years after the index revision total hip arthroplasty. The clinical and radiological results of revision total hip arthroplasties in these patients were evaluated.ResultsThe median Harris hip score increased from 60 points before revision total hip arthroplasties to 90 points at the final follow-up. Osteolysis was detected at an average of 9.3 years after revision total hip arthroplasties in 13 hips and acetabular cup loosening at average 9.8 years after revision total hip arthroplasties in 9 hips. With radiographic evidence of osteolysis and loosening as the end points, the 15-year survival rates were 28.2% and 56.0%, respectively.ConclusionsThe survival rate of revision total hip arthroplasty in patients with metallosis following a catastrophic failure of a PE liner was low. 相似文献
59.
Ji-Woong Noh Byoung-Sun Park Mee-Young Kim Lim-Kyu Lee Seung-Min Yang Won-Deok Lee Yong-Sub Shin Ju-Hyun Kim Jeong-Uk Lee Taek-Yong Kwak Tae-Hyun Lee Ju-Young Kim Jaehong Park Junghwan Kim 《Journal of Physical Therapy Science》2015,27(10):3223-3226
[Purpose] The purpose of the present study was to elucidate the muscle conditions such as
the isokinetic muscle of Korean ssireum athletes. [Subjects and Methods] This study
enrolled 25 elite ssireum athletes. We measured body composition and peak torque at an
angular speed at 60°/s using an isokinetic muscle strength dynamometer. [Results] The lean
body mass of the left upper limb was significantly higher than that of the right upper
limb. However, the lean body mass of the left lower limb was significantly lower than that
of the right lower limb. The peak torque for left elbow flexion was significantly higher
than that for right elbow flexion. Conversely, the peak torque for left elbow extension
was significantly lower than that for right elbow extension. Furthermore, the peak torque
for the left knee was significantly lower than that for the right knee for both flexion
and extension. [Conclusion] The data from this study elucidate in part the muscle
conditions of Korean ssireum athletes, which can be used to establish a reference for the
scientific study of sports physiotherapy.Key words: Isokinetic muscle strength, Ssireum athletes, Sports physiotherapy 相似文献
60.