全文获取类型
收费全文 | 42176篇 |
免费 | 4459篇 |
国内免费 | 2759篇 |
专业分类
耳鼻咽喉 | 312篇 |
儿科学 | 525篇 |
妇产科学 | 457篇 |
基础医学 | 4870篇 |
口腔科学 | 882篇 |
临床医学 | 5420篇 |
内科学 | 6087篇 |
皮肤病学 | 456篇 |
神经病学 | 1931篇 |
特种医学 | 1569篇 |
外国民族医学 | 17篇 |
外科学 | 4472篇 |
综合类 | 7275篇 |
现状与发展 | 13篇 |
一般理论 | 15篇 |
预防医学 | 3070篇 |
眼科学 | 1344篇 |
药学 | 4156篇 |
59篇 | |
中国医学 | 2513篇 |
肿瘤学 | 3951篇 |
出版年
2024年 | 171篇 |
2023年 | 812篇 |
2022年 | 1894篇 |
2021年 | 2462篇 |
2020年 | 1827篇 |
2019年 | 1543篇 |
2018年 | 1565篇 |
2017年 | 1439篇 |
2016年 | 1331篇 |
2015年 | 2002篇 |
2014年 | 2523篇 |
2013年 | 2336篇 |
2012年 | 3218篇 |
2011年 | 3505篇 |
2010年 | 2260篇 |
2009年 | 1885篇 |
2008年 | 2295篇 |
2007年 | 2224篇 |
2006年 | 2251篇 |
2005年 | 1910篇 |
2004年 | 1385篇 |
2003年 | 1201篇 |
2002年 | 1017篇 |
2001年 | 868篇 |
2000年 | 818篇 |
1999年 | 880篇 |
1998年 | 543篇 |
1997年 | 503篇 |
1996年 | 394篇 |
1995年 | 336篇 |
1994年 | 339篇 |
1993年 | 195篇 |
1992年 | 253篇 |
1991年 | 195篇 |
1990年 | 157篇 |
1989年 | 197篇 |
1988年 | 141篇 |
1987年 | 139篇 |
1986年 | 69篇 |
1985年 | 72篇 |
1984年 | 46篇 |
1983年 | 32篇 |
1982年 | 27篇 |
1981年 | 26篇 |
1980年 | 19篇 |
1979年 | 26篇 |
1978年 | 11篇 |
1977年 | 5篇 |
1975年 | 9篇 |
1974年 | 10篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
Adult-to-adult living donor liver transplantation using extended right lobe grafts. 总被引:11,自引:0,他引:11 下载免费PDF全文
C M Lo S T Fan C L Liu W I Wei R J Lo C L Lai J K Chan I O Ng A Fung J Wong 《Annals of surgery》1997,226(3):261-270
OBJECTIVE: The authors report their experience with living donor liver transplantation (LDLT) using extended right lobe grafts for adult patients under high-urgency situations. SUMMARY BACKGROUND DATA: The efficacy of LDLT in the treatment of children has been established. The major limitation of adult-to-adult LDLT is the adequacy of the graft size. A left lobe graft from a relatively small volunteer donor will not meet the metabolic demand of a larger recipient. METHODS: From May 1996 to November 1996, seven LDLTs, using extended right lobe grafts, were performed under high-urgency situations. All recipients were in intensive care units before transplantation with five having acute renal failure, three on mechanical ventilation, and all with hepatic encephalopathy. The median body weight for the donors and recipients was 58 kg (range, 41-84 kg) and 65 kg (range, 53-90 kg), respectively. The body weights of four donors were less than those of the corresponding recipients, and the lowest donor-to-recipient body weight ratio was 0.62:1. The extended right lobe graft was chosen because the left lobe volume was <40% of the ideal liver mass of the recipient. RESULTS: Median blood loss for the donors was 900 mL (range, 700-1600 mL) and hospital stay was 19 days (range, 8-22 days). Homologous blood transfusion was not required. Two donors had complications (one incisional hernia and one bile duct stricture) requiring reoperation after discharge. All were well with normal liver function 5 to 10 months after surgery. The graft weight ranged from 490 g to 1140 g. All grafts showed immediate function with normalization of prothrombin time and recovery of conscious state of the recipients. There was no vascular complication, but six recipients required reoperation. One recipient died of systemic candidiasis 16 days after transplantation and 6 (86%) were alive with the original graft at a median follow-up of 6.5 months (range, 5-10 months). CONCLUSIONS: When performed by a team with experience in hepatectomy and transplantation, LDLT, using an extended right lobe graft, can achieve superior results. The technique extends the success of LDLT from pediatric recipients to adult recipients and opens a new donor pool for adults to receive a timely graft of adequate function. 相似文献
82.
近红外线乳腺扫描对诊断乳腺癌,特别对早期乳癌具有高度的敏感性和诊断特异性,根据1500例证实的分析,近红外线乳腺扫描诊断率T1—T2期为95%;T1期直径<1cm及TO期乳癌诊断率为85%。 作者首先提出近红外线乳腺扫描的所见15种分型,本文叙述了近红外线乳腺检查的诊断原则及其诊断价值。 由于近红外线乳腺扫描具有高敏感性而且是无损害的简易的检查方法,我们认为应作为乳腺的常规检查及普查时的首选检查方法。 相似文献
83.
84.
用聚焦层析结合DEAE-Sephadex A-50离子交换层析,从正常人肝浸液中分离得两个精氨酸酶同工酶组分.经聚丙烯酰胺凝胶电泳(PAGE)鉴定从聚焦层析得到的第一峰同工酶组分为一条蛋白带,第二峰具有精氨酸酶活性的蛋白组分的主要蛋白带也极明显。各蛋白质成分向阴极电泳的前后顺序与从聚焦层析洗脱的先后次序一致。两型同工酶的比活力分别约为2050U/mg及790U/mg。用SDS-PAGE检测两型同工酶均由两种亚基组成,且分子量近似。 相似文献
85.
86.
S T Fan T K Choi E C Lai J Wong 《The Australian and New Zealand journal of surgery》1988,58(9):717-721
Forty-seven patients aged more than 75 years with acute pancreatitis were studied. The most common cause of acute pancreatitis was biliary tract stones. The clinical presentation and severity of the disease as judged by the number of poor prognostic factors were not different from the group of patients aged less than 75 years. The mortality rate in the older group was thrice that of the younger group (21.3% versus 7.24%). The higher mortality rate was explained by a higher incidence of deaths related to complications of biliary stones and coincidental diseases. Significantly more aged patients with mild disease died, indicating the limitation of predictive ability of the scoring system in acute pancreatitis of the aged. 相似文献
87.
Influence of age on the mortality from acute pancreatitis 总被引:6,自引:0,他引:6
The influence of age on the mortality rate of 268 patients with acute pancreatitis was studied. The hospital mortality rate for patients aged below 50 years was 5.9 per cent. The figure increased to 21.3 per cent in patients aged over 75; the high mortality was accounted for by a higher incidence of deaths related to concomitant medical or surgical diseases in the same hospital admission rather than to complications resulting directly from the pathological process of acute pancreatitis. When only deaths due to complications of acute pancreatitis were analysed, the mortality rate was not significantly different between the young and elderly groups. Moreover, the complication rate and the proportion of patients having severe disease (judged by the number of prognostic signs) were not higher in the elderly. Thus acute pancreatitis was intrinsically not more serious were it not for the presence of concomitant diseases with advanced age. 相似文献
88.
本文报导了1983~1984年北京市城区(宣武区),近郊区(西红门)和远郊区(大皮营)母乳脂质成分的测定结果,并结合乳母营养状况给予评价。 共测定了207例母乳比重,平均范围在1.018~1.023之间;测定了216例母乳的脂肪含量(g/100g乳),城区平均值为3.78,近郊区为3.31,远郊区为3.08,城区的显著较高;测定了194例母乳胆固醇含量,初乳的最高(23.4mg/100g乳),以后逐渐减低,到第三个月后达稳定水平(约10mg/100g乳),三个调查点的情况相同,测定了221例母乳的脂肪酸组成,其主要成分为油酸(29~37%),棕榈酸(17~25%)和亚油酸(12~25%),远郊区母乳中所含的必需脂肪酸显著较高。 统计分析证明三个地区的乳脂含量(%)与乳胆固醇含量(mg/100g乳)间有显著性相关(P<0.01);188例乳母的膳食脂肪摄入量(g/日或%kcal)与乳脂含量间也有显著性相关(P<0.05),此结果表明,北京城乡母乳的乳脂含量可能受膳食脂质与量的影响,其脂肪酸组成的特点是亚油酸含量高,反映了我国人民以素食为主的饮食习惯。乳中的必需脂肪酸供给量可满足婴儿所需,胆固醇供给量为70~85mg/d,可作为同龄婴儿自母乳摄入量的参考。 相似文献
89.
饮水锶对大鼠骨骼生长发育影响的实验研究 总被引:1,自引:0,他引:1
研究了高锶饮水对大鼠骨骼生长发育的影响。结果表明,饮水中锶浓度为5~500mg/L达12周可引起Wistar大鼠血清、尿、股骨、颌骨和牙齿中锶含量增高,呈明显的剂量-反应关系。同时,锶还可使骨骼钙含量降低,牙齿钙含量和骨骼的骨密度增高,以及除第12周雌性大鼠外血清钙水平下降。尚未发现锶对动物体重、体长、血清AKP活性、尿钙水平以及股骨弯曲断裂载荷的影响。然而,锶对动物骨骼生长发育影响性别之间存在差异,如在第12周染锶组雄性大鼠血清钙含量降低,而雌性大鼠升高;在第4周和第8周时,仅雄性大鼠尿Hop/Cr比值增高,而雌性大鼠维持于正常水平;Sr2+还使雄性大鼠颌骨骨密度增加,而雌性大鼠股骨骨密度增加。上述改变提示可能是动物性别之间在内分泌调节和代谢过程上不同的结果。 相似文献
90.
中国蒙,汉族酒依赖与醇脱氢酶和醛脱氢酶基因多态性的相关研究 总被引:7,自引:1,他引:6
为探讨醇脱氢酶(ADH)基因和醛脱氢酶(ALDH)基因多态性与酒依赖患病的相互关系,用耳血干血痕聚合酶链反应、等位基因特异性寡核苷酸探针方法,检测乙醇代谢酶ADH和ALDH基因型在我国蒙、汉民族酒依赖与非酒依赖者中分布频率。结果显示在酒依赖组(汉族52例,蒙族31例)与正常对照组(汉族48例,蒙族35例)之间:汉族的ALDH2基因型频率与等位基因频率的分布差异有非常显著性(P<0.01),而蒙族则表示为ADH2基因型频率与等位基因频率的分布差异有非常显著性(P<0.01)。这提示汉族酒依赖的发病与ALDH2基因有关,蒙族则与ADH2基因有关。 相似文献