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41.
Masahiro Saito Tomoyuki Koike Yasuaki Abe Kenichiro Nakagawa Takeshi Kanno Xiaoyi Jin Waku Hatta Kaname Uno Naoki Asano Akira Imatani Fumiyoshi Fujishima Atsushi Masamune 《Internal medicine (Tokyo, Japan)》2021,60(3):391
We herein report the first case of foveolar-type gastric adenocarcinoma that developed after the initiation of vonoprazan (VPZ). A 51-year-old man had heartburn at the first visit and reflux esophagitis endoscopically, so he started taking VPZ. An approximately 5-mm-sized reddish polyp with a raspberry-like morphology was detected at the anterior wall of the upper body of the stomach 156 weeks after starting maintenance therapy with VPZ 10 mg/day. It was diagnosed as foveolar-type gastric adenocarcinoma based on a biopsy. Another approximately 4-mm-sized foveolar-type gastric adenocarcinoma was also detected at the posterior wall of the middle body of the stomach. 相似文献
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43.
Indication of aortocoronary by-pass for coronary arterial obstruction due to Kawasaki disease 总被引:1,自引:0,他引:1
Atsuko Suzuki Tetsuro Kamiya Yasuo Ono Nagaharu Takahashi Yasuaki Naito Yoshiji Kou 《Heart and vessels》1985,1(2):94-100
Summary Six patients with coronary arterial lesions due to Kawasaki disease underwent aortocoronary by-pass grafting at our institute. Before surgery, all of them had been closely monitored for some years by means of selective coronary arteriography, thallium myocardial imaging, electrocardiography (treadmill and/or Holter), and two-dimensional echo cardiography. Based on this experience, we propose the following guidelines as an indication for aortocoronary by-pass in such patients. First, the following three conditions should be satisfied: 1) The progress of coronary arterial lesions has been documented by serial selective coronary arteriography; 2) redistribution to the perfusion defect has been detected on the delayed image in myocardial imaging; 3) no coronary arterial lesions distal to the graft site have been detected by coronary angiography. When these three conditions are satisfied, at least one of the following conditions must apply: 1) Localized stenosis in the left main trunk has progressed to critical stenosis; 2) there is occlusion of two or more vessels; 3) collateral vessels connecting to the peripheral portion of an occluded coronary artery arise from the peripheral part of a vessel with progressive localized stenosis; 4) progressive localized stenosis or critical stenosis has developed in the left anterior descending artery, in addition to significant stenosis in the right coronary artery. 相似文献
44.
Nobuhiro Takemae Tung Nguyen Long Thanh Ngo Yasuaki Hiromoto Yuko Uchida Vu Phong Pham Tsutomu Kageyama Shizuko Kasuo Shinichi Shimada Yasutaka Yamashita Kaoru Goto Hideyuki Kubo Vu Tri Le Hung Van Vo Hoa Thi Do Dang Hoang Nguyen Tsuyoshi Hayashi Aya Matsuu Takehiko Saito 《Archives of virology》2013,158(4):859-876
The antigenicity of the influenza A virus hemagglutinin is responsible for vaccine efficacy in protecting pigs against swine influenza virus (SIV) infection. However, the antigenicity of SIV strains currently circulating in Japan and Vietnam has not been well characterized. We examined the antigenicity of classical H1 SIVs, pandemic A(H1N1)2009 (A(H1N1)pdm09) viruses, and seasonal human-lineage SIVs isolated in Japan and Vietnam. A hemagglutination inhibition (HI) assay was used to determine antigenic differences that differentiate the recent Japanese H1N2 and H3N2 SIVs from the H1N1 and H3N2 domestic vaccine strains. Minor antigenic variation between pig A(H1N1)pdm09 viruses was evident by HI assay using 13 mAbs raised against homologous virus. A Vietnamese H1N2 SIV, whose H1 gene originated from a human strain in the mid-2000s, reacted poorly with post-infection ferret serum against human vaccine strains from 2000-2010. These results provide useful information for selection of optimal strains for SIV vaccine production. 相似文献
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48.
Tetsuro Sohda Takayuki Hanano Hisanori Miyamoto Yoko Kitano Kaoru Iwata Masanori Yokoyama Makoto Irie Yasuaki Takeyama Satoshi Shakado Shotaro Sakisaka 《Hepatology International》2008,2(2):258-261
An 80-year-old man was admitted to our hospital because of the rupture of the liver. Laboratory data showed iron-deficiency
anemia, although there was no liver dysfunction. A computed tomography scan showed large liver tumor with intraperitoneal
hemorrhage, and since a serum level of α-fetoprotein (AFP) was extremely high, we initially suspected a rupture of hepatocellular
carcinoma (HCC). Transarterial embolization was performed to stop bleeding from the tumor, followed by an endoscopic examination
that revealed advanced gastric cancer. Histological analysis revealed that both the gastric and the hepatic tumors were moderately
to poorly differentiated adenocarcinoma, as well as that both tumors were immunohistochemically positive for AFP. Finally,
we diagnosed AFP-producing gastric cancer associated with liver metastasis. Rupture of metastatic liver cancer is rare, and
accordingly, distinction from HCC is important, particularly for the cases of AFP-producing gastric cancer. 相似文献
49.
Norihiro Nishida Tsukasa Kanchiku Yoshihiko Kato Yasuaki Imajo Yuichiro Yoshida Syunichi Kawano Toshihiko Taguchi 《The journal of spinal cord medicine》2015,38(5):593-598
Objective
Cervical myelopathy due to ossification of the posterior longitudinal ligament (OPLL) is induced by static factors, dynamic factors, or a combination of both. We used a three-dimensional finite element method (3D-FEM) to analyze the stress distributions in the cervical spinal cord under static compression, dynamic compression, or a combination of both in the context of OPLL.Methods
Experimental conditions were established for the 3D-FEM spinal cord, lamina, and hill-shaped OPLL. To simulate static compression of the spinal cord, anterior compression at 10, 20, and 30% of the anterior–posterior diameter of the spinal cord was applied by the OPLL. To simulate dynamic compression, the OPLL was rotated 5°, 10°, and 15° in the flexion direction. To simulate combined static and dynamic compression under 10 and 20% anterior static compression, the OPLL was rotated 5°, 10°, and 15° in the flexion direction.Results
The stress distribution in the spinal cord increased following static and dynamic compression by cervical OPLL. However, the stress distribution did not increase throughout the entire spinal cord. For combined static and dynamic compression, the stress distribution increased as the static compression increased, even for a mild range of motion (ROM).Conclusion
Symptoms may appear under static or dynamic compression only. However, under static compression, the stress distribution increases with the ROM of the responsible level and this makes it very likely that symptoms will worsen. We conclude that cervical OPLL myelopathy is induced by static factors, dynamic factors, and a combination of both. 相似文献50.
Yasuaki Hattori M.D. Masayuki Imamura M.D. Takayoshi Tobe M.D. 《The American journal of gastroenterology》1992,87(2):195-200
Recently, gastrinoma cells were demonstrated to release gastrin when directly stimulated by secretin both in vivo and in vitro. In this study, the reaction of antral G cells was investigated. Secretin was injected into the right gastroepiploic artery in canines, and into the common hepatic artery during a selective arteriography in patients without gastrinomas. G cells obtained from the antrum of rats were attached to 0.45-microns filters and irrigated with medium containing secretin. The serum gastrin concentration increased rapidly in significant amounts and very quickly after an intraarterial injection of secretin, both in humans and in dogs. The rate of gastrin release from the rat antral G cells in vitro increased significantly when the medium contained secretin. In conclusion, secretin stimulated gastrin release from antral G cells both in vivo and in vitro. 相似文献