收费全文 | 4783619篇 |
免费 | 384340篇 |
国内免费 | 35820篇 |
耳鼻咽喉 | 65324篇 |
儿科学 | 147006篇 |
妇产科学 | 121804篇 |
基础医学 | 720721篇 |
口腔科学 | 129207篇 |
临床医学 | 450846篇 |
内科学 | 863120篇 |
皮肤病学 | 115529篇 |
神经病学 | 396797篇 |
特种医学 | 183532篇 |
外国民族医学 | 1005篇 |
外科学 | 708387篇 |
综合类 | 168079篇 |
现状与发展 | 97篇 |
一般理论 | 2690篇 |
预防医学 | 382806篇 |
眼科学 | 114095篇 |
药学 | 350457篇 |
326篇 | |
中国医学 | 29046篇 |
肿瘤学 | 252905篇 |
2021年 | 69648篇 |
2020年 | 48266篇 |
2019年 | 72371篇 |
2018年 | 87117篇 |
2017年 | 69438篇 |
2016年 | 75290篇 |
2015年 | 91968篇 |
2014年 | 128535篇 |
2013年 | 191874篇 |
2012年 | 147083篇 |
2011年 | 154897篇 |
2010年 | 142204篇 |
2009年 | 139074篇 |
2008年 | 132393篇 |
2007年 | 139691篇 |
2006年 | 148114篇 |
2005年 | 142325篇 |
2004年 | 137810篇 |
2003年 | 127271篇 |
2002年 | 115433篇 |
2001年 | 184292篇 |
2000年 | 180437篇 |
1999年 | 165119篇 |
1998年 | 76938篇 |
1997年 | 72161篇 |
1996年 | 69153篇 |
1995年 | 64364篇 |
1994年 | 57867篇 |
1993年 | 53196篇 |
1992年 | 116184篇 |
1991年 | 110329篇 |
1990年 | 105617篇 |
1989年 | 102971篇 |
1988年 | 94566篇 |
1987年 | 92328篇 |
1986年 | 86644篇 |
1985年 | 84296篇 |
1984年 | 69252篇 |
1983年 | 61349篇 |
1982年 | 48427篇 |
1981年 | 44946篇 |
1980年 | 41996篇 |
1979年 | 58377篇 |
1978年 | 46608篇 |
1977年 | 41700篇 |
1976年 | 38157篇 |
1975年 | 38457篇 |
1974年 | 41554篇 |
1973年 | 39596篇 |
1972年 | 37171篇 |
Background and aims
It is not known whether non alcoholic fatty liver disease (NAFLD) is a risk factor for diabetes in non obese, non centrally-obese subjects. Our aim was to investigate relationships between fatty liver, insulin resistance and a biomarker score for liver fibrosis with incident diabetes at follow up, in subjects who were neither obese nor centrally-obese.Methods and results
As many as 70,303 subjects with a body mass index (BMI) < 25 kg/m2 and without diabetes were followed up for a maximum of 7.9 years. At baseline, fatty liver was identified by liver ultrasound, insulin resistance (IR) by homeostatic model assessment of insulin resistance (HOMA-IR) ≥2.0, and central obesity by waist circumference (waist circumference ≥90 cm (men) and ≥85 cm (women). The Fibrosis-4 (FIB-4 score) was used to estimate extent of liver fibrosis. Cox proportional hazards models adjusted for confounders were used to estimate hazard ratios (aHRs) for incident diabetes. As many as 852 incident cases of diabetes occurred during follow up (median [IQR] 3.71 [2.03] years). Mean ± SD BMI was 22.8 ± 1.8 and 21.7 ± 2.0 kg/m2 in subjects with and without diabetes at follow up. In subjects without central obesity and with fatty liver, aHRs (95% CI) for incident diabetes at follow up were 2.17 (1.56, 3.03) for men, and 2.86 (1.50,5.46) for women. Similar aHRs for incident diabetes occurred with fatty liver, IR and the highest quartile of FIB-4 combined, in men; and there was a non significant trend toward increased risk in women.Conclusions
In normal weight, non-centrally obese subjects NAFLD is an independent risk factor for incident diabetes. 相似文献Research design and methods: A sample of 1139 reports received by the Shaanxi ADR Monitoring Center from January 2015 to December 2017 was selected. ADR report quality was evaluated using an ADR report quality evaluation system.
Results: None of the reports were rated as excellent and 1.40% (n = 16) as good. Report quality was better for new and serious reports than for general reports. Medical institutions generated higher quality reports than pharmaceutical manufacturers. Nurses generated higher quality reports than doctors, pharmacists, and other professionals. Reporters of different occupations showed significant differences in the quality of the indicators Reporting time limit, Intervention ADR time, ADR termination time, ADR intervention measures, Original disease, and Cause of medication (P = 0.000).
Conclusions: The ADR data quality was poor in western China, and of lower quality than reported data from previous research in other regions. Improvements in the quality and availability of ADR reports are urgently needed. 相似文献