对液化石油气燃烧产物接触者尿致突变性的研究

应用鼠伤寒沙门菌株ＴＡ９８及其新的衍生菌株ＹＧ１０２１和ＹＧ１０２４检测了液化石油气（ＬＰＧ）燃烧产物接触者尿的致突变性。吉果表明，在有大鼠Ｓ_９已β－葡萄糖醛酸酶存在时，尿样显示较强的致突变性。尿样对ＹＧ１０２４的致突变性明显高于ＴＡ９８，而对ＹＧ１０２１的致突变性与ＴＡ９８相近。提示ＬＰＧ燃烧产物接触者尿中致突变物主要是以葡萄糖醛酸贰结合状态存在的芳香胺类物质。同时也证明ＹＧ１０２４在检测该尿样的致突变性上比ＴＡ９８更为敏感。     

Prognosis-related analysis of renal pelvic cancer

Objective To promote the diagnosis and therapeutic results for renal pelvic cancer. Methods The prognosis-related factors in 47 cases with renal pelvic cancer were analyzed retrospectively. Results The overall 3 and 5-year survival rates for renal pelvic cancer patients were 65.9% (31/47) and 51.1% (24/47), respectively. The 5-year survival was 55% (23/40) in organ-confined cancer and 26.7% (2/7) with coexisting muiti -organ involvement (P>0.05). The 5-year survival was 38.7%( 12/31) in cases with a tumor >2.5 cm and 75%(12/16) in the cases with tumor ≤2.5 cm (P<0 05). The 5-year survival was 37.9% (11/29) in cases with serious hydronephrosis, which was significantly lower than the 72.2% (13/18) found in those with slight hydronephrosis (P <0.05). According to the histologicsl grade, the 5-year survival was 100% (6/6) in patients with a G1 tumor, 65.2% (15/23) with G2, and 16.7% (3/18) with G3 (P<0.01 ). Based on the pathologic stage, the 5-year survival of cases was 84.6% (11/13) with T1 tumors, 60% (12/20) with T2, and 7.1% (1/14) with T3-T4 (P<0.01). Patients with a G2T2 or higher staging tumor, who underwent radical nephroureterectomy with partial bladder resection by a transabdominal approach had a significantly higher 5-year survival than those; who underwent nephrectomy or nephroureterectomy with partial bladder resection via a lumbar approach (P <0.05). There was no significant difference between the 5 -year survival of patients with recurrence of bladder carcinoma compared to patients without recurrence (P>0.05). Conclusion The tumor grade and stage are the key points for prognosis. Radical nephroureterectomy with partial bladder resection is an effective method to improve the prognosis of patients with a high grade and high stage tumor.     

Calot三角的应用解剖学

本对50例成年尸体Calot三角的形状，内容和位置关系作了调查，并进行了讨论，尤其是对于胆囊动脉在Calot三角内的有关情况作了探讨。     

高锌摄入对正常小鼠生长发育、血液成份及免疫功能的影响

观察了高锌摄入对小鼠食量、体重、血液成份及免疫功能的影响，结果显示，连续给予高锌饲料（１．５ｇ／ｋｇ）３周后，可使小鼠食欲下降，体重增长延缓，饲料效价显著降低，血红蛋白和血钙含量明显减少，可明显增加血小板数量，升高血中胆固醇含量，并可导致脾肿大，抑制细胞吞噬功能，提示高锌对机体的危害。     

Early stent occlusion is not always caused by thrombosis

Early occlusion of intracoronary stents has been exclusively attributed to thrombosis. Using intracoronary angioscopy, we have found 2 patients in whom this common and serious complication of coronary stenting was caused by obstructive intima dissection rather than thrombosis. © 1993 Wiley-Liss, Inc.     

The Stroke Area: Feasibility of Adoption in Community Hospitals

Pioneering efforts to establish what are known as stroke areas in community hospitals were made primarily by Dr Charles Bonner at Youville Hospital in Cambridge, Massachusetts, and Dr. Bertram Howard at St. Luke''s Hospital in New Bedford, Massachusetts during the early 1960s. Analysis of comparative data collected in subsequent years from 15 or more hospitals that followed their lead suggests that the stroke unit concept has become recognized as a medically sound approach to the management of stroke victims toward enhancing, rather than simply trying to save lives.     

Translocating the aberrant right subclavian artery in dysphagia lusoria.

A case of dysphagia lusoria with unusual associated symptoms in an adult is presented. The condition was treated by division of the aberrant right subclavian artery at its origin through a median sternotomy and translocating the distal subclavian artery to the aortic arch with an interposition Dacron graft. All the reported techniques of dividing and transposing the aberrant right subclavian artery in dysphagia lusoria are reviewed and discussed.     

Aortic valvular disease. Comparison of types and their medical and surgical management

A seven year experience with pure aortic valvular disease in one hundred fifty-eight patients is reviewed. Three groups (pure aortic stenosis, combined aortic stenosis and insufficiency and pure aortic insufficiency) were contrasted as to etiology, clinical course, hemodynamic and cineangiographic data, and the results of medical versus surgical therapy.