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991.
992.
Thallium (Tl) is a highly toxic heavy metal, and its pollution and remediation in aquatic environments has attracted considerable attention. To reduce or remove Tl pollution in the environment, various strategies have been applied. Graphene oxide (GO) has abundant oxygen-containing functional groups, indicating its high application potential for pollution remediation via methods involving binding to metal ions or positively charged organic molecules or electrostatic interaction and coordination. However, the adsorption of Tl to GO occurs via physical adsorption, for which the adsorption efficiency is low. Therefore, herein, we report a new method to effectively remove Tl pollution in water. We combined GO with aza-crown ether, which enhanced the electronegativity and ability to bind metal ions. The functionalized graphene oxide (FGO) demonstrated high efficiency through a wide pH gradient of 5–10, with a dominant Tl(i) adsorption capacity (112.21 mg g−1) based on the Langmuir model (pH 9.0, adsorbent concentration of 0.8 g L−1). The adsorption of Tl(i) during removal fit a pseudo-second-order kinetic model well. The mechanisms of Tl removal involve physical and chemical adsorption. In summary, our study provides a new method for the detection and treatment of Tl-containing wastewater by using FGO.Thallium (Tl) is a highly toxic heavy metal, and its pollution and remediation in aquatic environments has attracted considerable attention. 相似文献
993.
The sulfur/nitrogen co-doped activated carbon fiber (S/N-ACF) is prepared by the thermal treatment of thiourea-bonded hydroxyl-rich carbon fiber, which can bond the decomposition products of thiourea through hydrogen bond interaction to avoid the significant loss of sulfur and nitrogen sources during the thermal treatment process. The sulfur/nitrogen co-doped carbon fiber (S/N-CF) is prepared by the thermal treatment of thiourea-adsorbed carbon fiber. The doping degree of the carbon fiber is improved by reasonable strategy. S/N-ACF shows a higher amount of S/N doping (4.56 at% N and 3.16 at% S) than S/N-CF (1.25 at% N and 0.61 at% S). S/N-ACF with high S/N doping level involves highly active sites to improve the capacitive performance, and high delocalization electron to improve the conductivity and rate capability when compared with the normal S/N co-doped carbon fiber (S/N-CF). Accordingly, the specific capacitance increases from 1196 mF cm−2 for S/N-CF to 2704 mF cm−2 for S/N-ACF at 1 mA cm−2. The all-solid-state flexible S/N-ACF supercapacitor achieves 184.7 μW h cm−2 at 350 μW cm−2. The results suggest that S/N-ACF has potential application as a CF-based supercapacitor electrode material.Sulfur/nitrogen co-doped activated carbon fiber is prepared by thermal treatment of thiourea-bonded hydroxyl-rich carbon fiber, which achieves high doping level and electrochemical performance. 相似文献
994.
To achieve superior lithium storage performance, SiOx is usually designed into nanostructured SiOx/C composites by complex or expensive methods. Here, micron-sized interconnected SiOx/N-doped carbon (NC) microspheres composed of evenly dispersed SiOx nano-domains and NC have been fabricated by a scalable microemulsion method and following pyrolysis, using vinyltriethoxysilane and chitosan as precursors. The unique structure of the micron-sized SiOx/NC spheres leads to enhanced structural integrity and enables stable long-term cycling (800 cycles at 2 A g−1). Benefiting from the enhanced electron/Li+ diffusion kinetics originated from the unique structure and N-doping, SiOx/NC-2 presents considerable capacitive-controlled Li storage capacity, which leads to outstanding rate capability. Consequently, the assembled SiOx/NC-2//LiFePO4 full cell exhibits superior rate capability (106 mA h g−1 at 4C) and stable long-term cycling at 2C (102 mA h g−1 after 350 cycles). This work opens a new door for the application of chitosan in building micron-sized high-performance SiOx/C anode materials, and to some extent facilitates the recycling of waste seafood shells.Chitosan is employed as a carbon precursor to fabricate micron-scale interconnected SiOx/NC spheres that exhibit excellent lithium storage performance. 相似文献
995.
996.
997.
Xingxing Meng Xi Zhang Yuting Su Zhenghui Gu Xiaoping Xie Yaoming Chang Junxiang Bao 《Clinical and experimental pharmacology & physiology》2020,47(9):1564-1574
Noise exposure relates to various pathological disorders including liver damage, preventive measures of which are being demanded. Hyperbaric oxygen treatment (HBOT), as a non-invasive procedure, exerts convincing therapeutic potency on multiple liver diseases. The efficacy of HBOT in mitigating noise induced liver damage (NILD) and associated mechanisms would be elucidated here. Mice were subject to broad band noise (20–20k Hz, 90–110 dB) for 5 days by 3 hours/day. HBOT with 2.5 atmosphere absolute (ata) was employed before noise exposure. Morphology of liver tissue was examined by hematoxylin-eosin (HE) staining. Oil Red O (ORO), transferase-mediated dUTP nick end labelling (TUNEL) test and western blot were utilized to detect lipid accumulation, apoptotic cells and protein expression, respectively. Ceramide (Cer) level was assayed by immunohistochemistry (IHC) analysis. With noise exposure, conspicuous structural derangement and lipid deposition occurred in liver tissue of mice, which was alleviated significantly by the application of HBOT. Meanwhile, HBOT reduced the proportion of apoptotic hepatocytes, restraining the superoxide production in noise exposed mice. In view of underlying mechanisms, noise enhanced the acid sphingomyelinase (ASM) protein expression and the Cer generation in liver tissue of mice which was reversed substantially by HBOT. Altogether, HBOT ameliorates the structural and functional derangement of liver by neutralizing the ASM/Cer pathway in noise exposed mice. 相似文献
998.
Tian Wang Jianan Li Ruotian Xie Jiaxing Wang Wei Zhang Feng Jiang Mei Du Xiaohong Wang Bo Huang Rodrigo Brant Cheng Zhang Hua Yan 《Clinical and experimental pharmacology & physiology》2020,47(6):966-976
Tumour necrosis factor ligand related molecule 1 A (TL1A), a member of tumour necrosis factor superfamily, has been identified as a crucial regulator for vascular homeostasis and inflammation. However, the function of TL1A in diabetic retinopathy (DR) is largely unknown. This study aims to examine levels of TL1A in serum and intraocular fluid in patients with proliferative diabetic retinopathy (PDR), and to explore the correlation of intraocular TL1A with the prognosis of PDR progression after primary vitrectomy. Seventy-five patients (75 eyes) with PDR who underwent pars plana vitrectomy (PPV) and 19 patients (19 eyes) who received vitrectomy for idiopathic macular holes (IMH) as non-diabetic control group were enrolled in this prospective study. Serum, aqueous and vitreous fluid samples were collected during cataract and PPV surgery. Protein expressions of TL1A as well as other angiogenic and inflammatory cytokines in serum and intraocular fluid were measured. Correlations of intraocular TL1A concentrations with inflammatory cytokines were analyzed. We found both aqueous and vitreous TL1A levels were significantly higher in the PDR group than in control group (Paqueous = 0.026; Pvitreous <0.001). Angiogenic and inflammatory cytokines such as VEGF, IL-6, IL-8, MCP-1, MIP-1α, and MIP-1β were significantly higher in intraocular fluid in PDR group than in controls, which MCP-1 and MIP-1α showed positive correlation with intraocular TL1A levels. There is no significant difference in the levels of serum TL1A as well as other inflammatory cytokines between PDR patients and controls. Intraocular levels of TL1A were significantly lower in PDR progression group than in the stable group (Paqueous <0.001; Pvitreous <0.001). Multivariate logistic regression analyses revealed that lower levels of intraocular TL1A was an important risk factor for predicting PDR progression after primary PPV (ORaqueous = 0.717, Paqueous = 0.001; ORvitreous = 0.684; Pvitreous = 0.002). In conclusion, TL1A and multiple inflammatory cytokines were highly enriched in the intraocular fluid of PDR patients compared with the controls. Lower levels of intraocular TL1A were associated with development of PDR complications after primary PPV and might be used as prognostic factor in predicting the vitrectomy outcome in PDR patients. 相似文献
999.
Ling Liu Zhenni Ma Xuemei Zhou Jie Yin Jun Lu Jian Su Fei Shen Liqian Xie Shaoyan Hu Jing Ling 《Clinical and experimental pharmacology & physiology》2020,47(8):1402-1409
A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAMTS13) was mainly generated and secreted from endothelial cells (ECs). Our previous study showed that tryptophan (Trp) residues at 387 and 390 in ADAMTS13 are required for its secretion and enzymatic activity. However, the effects on its host cell as well as the potential mechanism have not been clear. The aim of the study was to examine the effects of Trp residues 387 and 390 of ADAMTS13 on the biological processes of ECs. Herein, Trp was substituted with alanine in ADAMTS13 to generate ADAMTS13 mutants at 387 (W387A), 390 (W390A), and double mutants at 387 and 390 (2WA), respectively. We found that substitution mutation impaired vascular endothelial growth factor (VEGF) secretion and the downstream JAK1/STAT3 activation, the binding ability to Von Willebrand factor, cell proliferation, migration, and vascular tube formation. Overall, our study concluded that Trp387 and Trp390 of ADAMTS13 play vital roles in the biological function of ECs. 相似文献
1000.