全文获取类型
收费全文 | 1284篇 |
免费 | 224篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 52篇 |
妇产科学 | 15篇 |
基础医学 | 88篇 |
口腔科学 | 19篇 |
临床医学 | 237篇 |
内科学 | 312篇 |
皮肤病学 | 34篇 |
神经病学 | 74篇 |
特种医学 | 83篇 |
外科学 | 210篇 |
综合类 | 58篇 |
现状与发展 | 20篇 |
预防医学 | 95篇 |
眼科学 | 34篇 |
药学 | 64篇 |
中国医学 | 2篇 |
肿瘤学 | 116篇 |
出版年
2024年 | 7篇 |
2023年 | 44篇 |
2022年 | 8篇 |
2021年 | 28篇 |
2020年 | 26篇 |
2019年 | 15篇 |
2018年 | 61篇 |
2017年 | 45篇 |
2016年 | 34篇 |
2015年 | 46篇 |
2014年 | 48篇 |
2013年 | 80篇 |
2012年 | 32篇 |
2011年 | 44篇 |
2010年 | 56篇 |
2009年 | 71篇 |
2008年 | 41篇 |
2007年 | 48篇 |
2006年 | 47篇 |
2005年 | 41篇 |
2004年 | 28篇 |
2003年 | 36篇 |
2002年 | 32篇 |
2001年 | 30篇 |
2000年 | 19篇 |
1999年 | 34篇 |
1998年 | 30篇 |
1997年 | 35篇 |
1996年 | 49篇 |
1995年 | 33篇 |
1994年 | 19篇 |
1993年 | 25篇 |
1992年 | 18篇 |
1991年 | 18篇 |
1990年 | 17篇 |
1989年 | 28篇 |
1988年 | 27篇 |
1987年 | 27篇 |
1986年 | 14篇 |
1985年 | 22篇 |
1984年 | 12篇 |
1983年 | 11篇 |
1982年 | 13篇 |
1981年 | 8篇 |
1980年 | 8篇 |
1978年 | 14篇 |
1977年 | 11篇 |
1976年 | 13篇 |
1975年 | 8篇 |
1964年 | 6篇 |
排序方式: 共有1526条查询结果,搜索用时 15 毫秒
991.
992.
993.
994.
995.
996.
997.
D. R. Lachno H. Vanderstichele G. De Groote V. Kostanjevecki G. De Meyer E. R. Siemers M. B. Willey J. S. Bourdage R. J. Konrad R. A. Dean 《The journal of nutrition, health & aging》2009,13(3):220-225
Objective The aim of the study was to determine the extent to which plasma matrix types, diurnal rhythm and sample collection and processing
procedures contribute to overall variability of measurements with the INNO-BIA plasma Aβ forms assay.
Methods Plasma samples from healthy volunteers were collected at BARC-CRI. Analyte concentrations from various plasma matrix types
(EDTA, heparin, fluoride) were compared to serum after collection of blood in commercial plastic and glass tubes. Sample processing
variables including time and temperature before and after centrifugation, centrifugal force and plasma dilution factor were
also investigated. Diurnal variability in plasma Aβ isoforms was determined in 29 healthy volunteers by analysis of EDTA plasma
specimens serially collected over 24 hours and stored frozen following oral administration of a placebo treatment. All plasma
samples from a given individual and experiment were analyzed in a single analytical run.
Results Highest Aβ levels were obtained using EDTA-plasma samples (in contrast to serum, heparin, citrate, or fluoride). Addition
of aprotinin to EDTA plasma had no effect on Aβ peptide recovery. The elapsed time and temperature exposure, before and after
sample processing affects the recovery of Aβ isoforms. Analyte recovery was not significantly affected by the presence of
platelets in plasma samples. At the subject level, analysis of serially collected EDTA plasma specimens from healthy volunteers
revealed no evidence of diurnal variation in any of the Aβ isoforms investigated and results from samples collected on a monthly
basis showed only very limited intra-individual variation.
Conclusions Optimal recovery of Aβ peptides was obtained from blood drawn into EDTA tubes and processed within 4 h. Plasma that was refrigerated
after separation and analysed within 4 h gave comparable results to samples immediately processed and frozen at −70 °C. 相似文献
998.
BM Button RG Heine AG Catto-Smith PD Phelan A Olinsky 《Archives of disease in childhood》1997,76(2):148-150
Gastro-oesophageal reflux is increased in cystic fibrosis and it is possible that postural drainage techniques may exacerbate reflux, potentially resulting in aspiration and further impairment of pulmonary function. AIM: To evaluate the effects of physiotherapy with head down tilt (standard physiotherapy, SPT) on gastroesophageal reflux and to compare this with physiotherapy without head down tilt (modified physiotherapy, MPT). METHOD: Twenty (mean age 2.1 months) infants with cystic fibrosis underwent 30 hour oesophageal pH monitoring during which SPT and MPT were carried out for two sessions each on consecutive days. RESULTS: The number of reflux episodes per hour, but not their duration, was significantly increased during SPT compared with MPT (SPT 2.5 (0.4) v MPT 1.6 (0.3), p = 0.007) and to background (1.1 (0.)1, p = 0.0005). Fractional reflux time was also increased during SPT (11.7 (2.6)%) compared with background (6.9 (1.3)%) p = 0.03) but not compared with MPT (10.7 (2.7)%). There was no significant difference between MPT and background for number of reflux episodes, their duration, or fractional reflux time. CONCLUSIONS: SPT, but not MPT, was associated with a significant increase in gastro-oesophageal reflux in infants with cystic fibrosis. 相似文献
999.
1000.
B. C. Guard BM MRCP FRCA Registrar S. J. Wiltshire MB BS FRCA Consultant 《Anaesthesia》1996,51(12):1173-1175
In order to evaluate the contribution of tubal spasm to pelvic pain following laparoscopic sterilisation, we have studied the effect of glycopyrrolate, an anticholinergic agent with antispasmodic properties, on 60 ASA 1 and 2 patients presenting as day-cases for laparoscopic sterilisation using Filshie clips. In a randomised, double-blind, controlled trial, patients received either glycopyrrolate 0.3mg or saline intravenously prior to induction of anaesthesia. Compared with the control group, patients receiving glycopyrrolate had significantly reduced immediate postoperative pain scores (p < 0.02) and required significantly less postoperative morphine (p < 0.01). Nausea, vomiting and anti-emetic requirements were also reduced though not significantly. We conclude that glycopyrrolate 0.3mg at induction of anaesthesia is an effective method of improving the quality of recovery after day-case laparoscopic sterilisation using clips. 相似文献