全文获取类型
收费全文 | 33809篇 |
免费 | 4704篇 |
国内免费 | 193篇 |
专业分类
耳鼻咽喉 | 626篇 |
儿科学 | 742篇 |
妇产科学 | 590篇 |
基础医学 | 3206篇 |
口腔科学 | 941篇 |
临床医学 | 6106篇 |
内科学 | 6975篇 |
皮肤病学 | 916篇 |
神经病学 | 2521篇 |
特种医学 | 1279篇 |
外科学 | 4792篇 |
综合类 | 813篇 |
现状与发展 | 2篇 |
一般理论 | 24篇 |
预防医学 | 4366篇 |
眼科学 | 451篇 |
药学 | 2163篇 |
1篇 | |
中国医学 | 123篇 |
肿瘤学 | 2069篇 |
出版年
2023年 | 503篇 |
2022年 | 259篇 |
2021年 | 612篇 |
2020年 | 690篇 |
2019年 | 504篇 |
2018年 | 926篇 |
2017年 | 862篇 |
2016年 | 946篇 |
2015年 | 1080篇 |
2014年 | 1218篇 |
2013年 | 1847篇 |
2012年 | 1498篇 |
2011年 | 1439篇 |
2010年 | 1121篇 |
2009年 | 1189篇 |
2008年 | 1323篇 |
2007年 | 1263篇 |
2006年 | 1341篇 |
2005年 | 1274篇 |
2004年 | 1158篇 |
2003年 | 1077篇 |
2002年 | 1057篇 |
2001年 | 1148篇 |
2000年 | 1109篇 |
1999年 | 988篇 |
1998年 | 564篇 |
1997年 | 535篇 |
1996年 | 540篇 |
1995年 | 490篇 |
1994年 | 372篇 |
1993年 | 322篇 |
1992年 | 690篇 |
1991年 | 709篇 |
1990年 | 654篇 |
1989年 | 603篇 |
1988年 | 551篇 |
1987年 | 532篇 |
1986年 | 520篇 |
1985年 | 521篇 |
1984年 | 383篇 |
1983年 | 335篇 |
1982年 | 246篇 |
1981年 | 248篇 |
1979年 | 334篇 |
1978年 | 250篇 |
1977年 | 216篇 |
1974年 | 218篇 |
1973年 | 207篇 |
1972年 | 176篇 |
1971年 | 196篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
41.
42.
Diana H. Yu BA ; Kimberly A. Mace PhD ; Scott L. Hansen MD ; Nancy Boudreau PhD ; David M. Young MD 《Wound repair and regeneration》2007,15(5):628-635
Insulin-like growth factor-1 (Igf-1), a critical mediator of tissue repair, is significantly decreased in diabetic wounds. Furthermore, decreased levels of hypoxia-inducible factor 1-alpha (Hif-1alpha) and its target genes are also associated with impaired wound healing in diabetic mice. The aim of our study was to examine whether the reduced levels of Igf-1 are responsible for the reduction in Hif-1alpha protein synthesis and activity in diabetic wounds. We provide evidence that Igf-1 regulates Hif-1alpha protein synthesis and activity during wound repair. In addition, Igf-1 stimulated phosphytidylinositol 3-kinase activity in diabetic fibroblasts, which, in turn, increased activation of the translational regulatory protein, p70 S6 kinase. Moreover, improved healing of diabetic wounds by addition of recombinant IGF-1 protein was associated with an increase in Hif-1alpha protein synthesis and function in vivo. 相似文献
43.
Qualitative Data Analysis: An Introduction 总被引:1,自引:1,他引:0
44.
45.
M. S. Reddy S. A. White B. C. Jaques N. Torpey D. M. Manas 《American journal of transplantation》2007,7(10):2422-2424
As demand for donor pancreases increases, attempts are being made to utilize even marginal grafts for transplantation. Injury during pancreas recovery can predispose to posttransplant complications and graft loss. Early recognition and correction can salvage these grafts. The authors report an instance of poor segmental perfusion of the pancreas graft that was salvaged by pancreas head resection and enteric drainage through a Roux-en-Y pancreatico-jejunostomy. 相似文献
46.
Ruth McDonald BA MSc PhD Stephen Harrison BSc MPhil PhD 《Health & social care in the community》2004,12(3):194-201
Recent New Labour policy for the ‘modernisation’ of Government places a good deal of emphasis on decentralisation. This emphasis is particularly marked in relation to the organisation of primary care. However, like hospitals and other National Health Service institutions, primary care trusts (PCTs) are subject to a substantial raft of centrally established performance targets and indicators, including those which contribute to the public award of between zero and three performance ‘stars’. This raises questions about the extent to which employees can exercise autonomy in the context of rigid top‐down directives. This paper presents findings from a study using participant observation and interviews to examine the impact of a training course aimed ostensibly at increasing employee autonomy in an English PCT. The suggestion is that attempts to make employees more autonomous can be seen as a strategy for increasing central control based upon the internalisation by the employees of centrally promulgated values. The attraction of such strategies is that they may be potentially more effective and less costly than alternative strategies of direct control. However, the study suggests that the outcome of attempts by such methods as programmes to increase employee autonomy may be very different from those intended. 相似文献
47.
Starling III John BA Patel Purvisha J. MD Rasberry Ron D. MD 《Dermatologic surgery》2005,31(4):484-485
BACKGROUND: Simple surgical excision is one of the most common treatment methods in the dermatologist's armamentarium. We describe a precise postsurgical dressing technique that can be used for wound care of those patients whose treatment involves removal of lesions via cutaneous surgery. OBJECTIVE: To devise a novel, precise, and effective dressing technique for postsurgical wound care. MATERIALS AND METHODS: We describe the technique using common in-office instruments. RESULTS AND CONCLUSION: Wound dressings for lesions located on curved areas such as the ears, nose, cheeks, and chin often exhibit less than adequate adherence and stability. The kerf-cut dressing technique optimizes pliability of dressing tape, and this maximizes efficient and stable application of postsurgical wound dressings to curved areas of the body. 相似文献
48.
49.
Vanaporn Wuthiekanun Varunee Desakorn Gumphol Wongsuvan Premjit Amornchai Allen C. Cheng Bina Maharjan Direk Limmathurotsakul Wirongrong Chierakul Nicholas J. White Nicholas P. J. Day Sharon J. Peacock 《Clinical and Vaccine Immunology : CVI》2005,12(4):555-556
An immunofluorescent (IF) method that detects Burkholderia pseudomallei in clinical specimens within 10 min was devised. The results of this rapid method and those of an existing IF method were prospectively compared with the culture results for 776 specimens from patients with suspected melioidosis. The sensitivities of both IF tests were 66%, and the specificities were 99.5 and 99.4%, respectively. 相似文献
50.
Patient-controlled analgesia. Does a concurrent opioid infusion improve pain management after surgery? 总被引:4,自引:0,他引:4
OBJECTIVE.--To assess the influence of a continuous (basal) morphine infusion as part of a patient-controlled analgesia (PCA) system on the postoperative analgesic requirement and on recovery parameters following abdominal hysterectomy. DESIGN.--Single-center, randomized, controlled protocol. SETTING.--University medical center. PARTICIPANTS.--A total of 230 adult women were randomly assigned to receive no morphine infusion (control group) or a continuous 0.5-, 1.0-, or 2.0-mg/h morphine infusion. Each patient was able to self-administer supplemental intravenous bolus doses of morphine (1 to 2 mg) using a PCA infuser. MAIN OUTCOME MEASURES.--Use of the PCA device, opioid-related side effects, recovery times, and the patients' assessment of pain and sedation on linear visual analog scales were recorded during the 72-hour study period. Follow-up questionnaires were completed by the patients and their health care professionals to assess the overall adequacy of PCA therapy. RESULTS.--Patients who received the 2-mg/h morphine infusions received significantly more opioid medication 9 to 72 hours after their operation than those who received no infusion (control group). The presence of a continuous morphine infusion of 0.5 to 2 mg/h did not significantly decrease the number of patient demands or supplemental bolus doses administered compared with the control group. Overall, 168 (84%) of the 199 patients who completed the 72-hour study were able to achieve adequate analgesia without requiring changes in the PCA regimen or experiencing major side effects. Recovery times and outcome variables were similar in all four groups. CONCLUSION.--The routine use of a continuous opioid infusion in combination with a standard PCA regimen does not improve pain management compared with PCA alone after abdominal hysterectomy. 相似文献