全文获取类型
收费全文 | 518122篇 |
免费 | 46109篇 |
国内免费 | 36886篇 |
专业分类
耳鼻咽喉 | 4477篇 |
儿科学 | 5139篇 |
妇产科学 | 7199篇 |
基础医学 | 63289篇 |
口腔科学 | 8770篇 |
临床医学 | 73108篇 |
内科学 | 76604篇 |
皮肤病学 | 4784篇 |
神经病学 | 28947篇 |
特种医学 | 18960篇 |
外国民族医学 | 339篇 |
外科学 | 51075篇 |
综合类 | 83653篇 |
现状与发展 | 116篇 |
一般理论 | 45篇 |
预防医学 | 31471篇 |
眼科学 | 15695篇 |
药学 | 53829篇 |
554篇 | |
中国医学 | 29378篇 |
肿瘤学 | 43685篇 |
出版年
2024年 | 1573篇 |
2023年 | 7632篇 |
2022年 | 20117篇 |
2021年 | 25091篇 |
2020年 | 18899篇 |
2019年 | 16711篇 |
2018年 | 17668篇 |
2017年 | 15800篇 |
2016年 | 14757篇 |
2015年 | 22390篇 |
2014年 | 27922篇 |
2013年 | 24160篇 |
2012年 | 35918篇 |
2011年 | 41183篇 |
2010年 | 25451篇 |
2009年 | 19830篇 |
2008年 | 27002篇 |
2007年 | 27210篇 |
2006年 | 27649篇 |
2005年 | 27575篇 |
2004年 | 17133篇 |
2003年 | 15852篇 |
2002年 | 13621篇 |
2001年 | 12296篇 |
2000年 | 13648篇 |
1999年 | 14963篇 |
1998年 | 9389篇 |
1997年 | 9413篇 |
1996年 | 7344篇 |
1995年 | 6867篇 |
1994年 | 5669篇 |
1993年 | 3772篇 |
1992年 | 4753篇 |
1991年 | 4027篇 |
1990年 | 3471篇 |
1989年 | 2983篇 |
1988年 | 2526篇 |
1987年 | 2177篇 |
1986年 | 1758篇 |
1985年 | 1435篇 |
1984年 | 821篇 |
1983年 | 557篇 |
1982年 | 341篇 |
1981年 | 327篇 |
1980年 | 250篇 |
1979年 | 296篇 |
1978年 | 82篇 |
1977年 | 89篇 |
1974年 | 102篇 |
1973年 | 83篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
Dan-Feng Xu Bing Wu Jin-Xin Wang Jian Yu Jian-Xin Xie 《World Journal of Clinical Cases》2021,9(5):1096-1102
BACKGROUNDGuillain-Barré syndrome (GBS) is a rare disorder that typically presents with ascending weakness, pain, paraesthesias, and numbness, which mimic the findings in lumbar spinal stenosis. Here, we report a case of severe lumbar spinal stenosis combined with GBS.CASE SUMMARYA 70-year-old man with a history of lumbar spinal stenosis presented to our emergency department with severe lower back pain and lower extremity numbness. Magnetic resonance imaging confirmed the diagnosis of severe lumbar spinal stenosis. However, his symptoms did not improve postoperatively and he developed dysphagia and upper extremity numbness. An electromyogram was performed. Based on his symptoms, physical examination, and electromyogram, he was diagnosed with GBS. After 5 d of intravenous immunoglobulin (0.4 g/kg/d for 5 d) therapy, he gained 4/5 of strength in his upper and lower extremities and denied paraesthesias. He had regained 5/5 of strength in his extremities when he was discharged and had no symptoms during follow-up.CONCLUSIONGBS should be considered in the differential diagnosis of spinal disorder, even though magnetic resonance imaging shows severe lumbar spinal stenosis. This case highlights the importance of a careful diagnosis when a patient has a history of a disease and comes to the hospital with the same or similar symptoms. 相似文献
12.
13.
Yulong Lian Jing Xiao Chen Zhang Suzhen Guan Fuye Li Hua Ge 《Archives of environmental & occupational health》2016,71(2):74-84
The present study compared the level of occupational strain and work ability among Han, Hui, Uygur, Hui, and Kazakh teachers, and explored ethnic differences based on the associations of psychosocial factors at work, occupational strain, and work ability. A cross-sectional survey was conducted among 2,941 teachers in primary and secondary schools in Xinjiang Province, China. Psychosocial factors, occupational strain, and work ability were measured using the Occupation Stress Inventory—Revised Edition (OSI-R) and Work Ability Index. Han and Hui teachers experienced reduced work ability compared with Uygur and Kazakh teachers, and this finding was caused, in part, by exposure to psychosocial factors at work. The vocational and psychological strains caused by these factors play an important role in reduced work ability among all ethnic teacher groups. The findings indicate the importance of taking action to reduce occupational strain for promoting teachers' work ability in multiethnic workplaces. 相似文献
14.
15.
16.
17.
Edward J. Holland Walter O. Whitley Kenneth Sall Stephen S. Lane Aparna Raychaudhuri Steven Y. Zhang 《Current medical research and opinion》2016,32(10):1759-1765
Objective: Report efficacy findings from three clinical trials (one phase 2 and two phase 3 [OPUS-1, OPUS-2]) of lifitegrast ophthalmic solution 5.0% for treatment of dry eye disease (DED).Research design and methods: Three 84-day, randomized, double-masked, placebo-controlled trials. Adults (≥18 years) with DED were randomized (1:1) to lifitegrast 5.0% or matching placebo. Changes from baseline to day 84 in signs and symptoms of DED were analyzed.Main outcome measures: Phase 2, pre-specified endpoint: inferior corneal staining score (ICSS; 0–4); OPUS-1, coprimary endpoints: ICSS and visual-related function subscale (0–4 scale); OPUS-2, coprimary endpoints: ICSS and eye dryness score (EDS, VAS; 0–100).Results: Fifty-eight participants were randomized to lifitegrast 5.0% and 58 to placebo in the phase 2 trial; 293 to lifitegrast and 295 to placebo in OPUS-1; 358 to lifitegrast and 360 to placebo in OPUS-2. In participants with mild-to-moderate baseline DED symptomatology, lifitegrast improved ICSS versus placebo in the phase 2 study (treatment effect, 0.35; 95% CI, 0.05–0.65; p?=?0.0209) and OPUS-1 (effect, 0.24; 95% CI, 0.10–0.38; p?=?0.0007). Among more symptomatic participants (baseline EDS ≥40, recent artificial tear use), lifitegrast improved EDS versus placebo in a post hoc analysis of OPUS-1 (effect, 13.34; 95% CI, 2.35–24.33; nominal p?=?0.0178) and in OPUS-2 (effect, 12.61; 95% CI, 8.51–16.70; p?<?0.0001).Limitations: Trials were conducted over 12 weeks; efficacy beyond this period was not assessed.Conclusions: Across three trials, lifitegrast improved ICSS in participants with mild-to-moderate baseline symptomatology in two studies, and EDS in participants with moderate-to-severe baseline symptomatology in two studies. Based on the overall findings from these trials, lifitegrast shows promise as a new treatment option for signs and symptoms of DED. 相似文献
18.
19.
20.