全文获取类型
收费全文 | 22033篇 |
免费 | 1434篇 |
国内免费 | 51篇 |
专业分类
耳鼻咽喉 | 250篇 |
儿科学 | 561篇 |
妇产科学 | 375篇 |
基础医学 | 3115篇 |
口腔科学 | 870篇 |
临床医学 | 2043篇 |
内科学 | 4407篇 |
皮肤病学 | 409篇 |
神经病学 | 1892篇 |
特种医学 | 1045篇 |
外国民族医学 | 25篇 |
外科学 | 2852篇 |
综合类 | 161篇 |
一般理论 | 6篇 |
预防医学 | 2270篇 |
眼科学 | 223篇 |
药学 | 1722篇 |
中国医学 | 72篇 |
肿瘤学 | 1220篇 |
出版年
2022年 | 209篇 |
2021年 | 396篇 |
2020年 | 263篇 |
2019年 | 337篇 |
2018年 | 425篇 |
2017年 | 328篇 |
2016年 | 373篇 |
2015年 | 456篇 |
2014年 | 566篇 |
2013年 | 756篇 |
2012年 | 1125篇 |
2011年 | 1127篇 |
2010年 | 643篇 |
2009年 | 649篇 |
2008年 | 1041篇 |
2007年 | 986篇 |
2006年 | 1015篇 |
2005年 | 985篇 |
2004年 | 908篇 |
2003年 | 857篇 |
2002年 | 805篇 |
2001年 | 599篇 |
2000年 | 627篇 |
1999年 | 535篇 |
1998年 | 234篇 |
1997年 | 177篇 |
1996年 | 144篇 |
1995年 | 170篇 |
1994年 | 204篇 |
1993年 | 267篇 |
1992年 | 609篇 |
1991年 | 560篇 |
1990年 | 462篇 |
1989年 | 317篇 |
1988年 | 298篇 |
1987年 | 289篇 |
1986年 | 240篇 |
1985年 | 280篇 |
1984年 | 217篇 |
1983年 | 157篇 |
1982年 | 130篇 |
1979年 | 174篇 |
1978年 | 140篇 |
1977年 | 134篇 |
1976年 | 137篇 |
1975年 | 145篇 |
1974年 | 183篇 |
1973年 | 155篇 |
1971年 | 138篇 |
1970年 | 126篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
92.
H. Klüter I. Dörges E. Maass T. Wagner H. Bartels H. Kirchner 《Annals of hematology》1996,73(2):85-89
Random-donor platelet concentrates (PC) prepared from pooled buffy coats have recently been described as an alternative method
for platelet preparation. We evaluated such PCs in the clinical setting compared with a standard PC from platelet apheresis.
PCs were prepared either from pools of buffy coats (BC-PC) or from single donors (SD-PC) with the cell separator CS-3000 plus.
PCs were stored for up to 5 days before transfusion. We compared fresh PC (day 1) with stored (day 2–3) and long-stored PC
(day 4–5). For analysis, platelet increment in the recipient was determined immediately and 16–22 h (mean 20 h) after transfusion,
corrected for total body area and transfused platelets (CCI). A total of 316 PCs were administered to 36 thrombocytopenic
patients suffering from various hematological disorders. Patients with detectable HLA or platelet-specific antibodies or splenomegaly
were excluded from the study. Mean platelet content of the PC was 262×109 for BC-PC and 251×109 for SD-PC. The 20-h CCI after transfusion of fresh PC was slightly higher with BC-PC than with SD-PC (14.5 versus 11.9;p=0.19), but values did not differ significantly between the two types of PC on any day of storage. For BC-PC, 20-h CCI decreased
with further storage by 30% (10.2;p=0.02). For SD-PC a decrease by 9% was not significant. In conclusion, platelet concentrates prepared from pools of buffy
coats showed excellent transfusion results when administered fresh, but storage decreased the CCI by 30%. No significant difference
from PCs from plateletpheresis was observed on any day of storage. Both types of platelet concentrates were capable of sufficient
platelet increment even when stored for up to 5 days.
Received: 28 December 1995 / Accepted: 14 May 1996 相似文献
93.
Abstract –This study investigated whether two new composite dental indicators -"the number of functioning teeth" and "the number of sound-equivalent teeth" are more efficient than the conventional DM FT index in revealing the social and behavioural factors which are significantly related to oral health status. The arbitrary set of weights given to the T-Health indicator was also evaluated. The number of functioning teeth was defined as the aggregate of filled (otherwise sound) and sound teeth. The T-Health was defined as a weighted average of sound teeth, filled (otherwise sound) teeth and teeth with some decay, the weights intended in principle to represent the relative amounts of sound tissue in these three categories of teeth. An arbitrary set of weights was used: 4, 2, and 1 for sound, filled, and decayed teeth, respectively. 164 families (father, mother and at least one 13-yr-old child) from Belo Horizonte, Brazil, were randomly selected from 13-yr-old children from private and state schools. The parents'ages ranged from 35 to 44 yr. Socio-economic status, area of residence, level of education, family income, sugar consumption, toothbrushing frequency and type of dental attendance were the social and behavioural oral health risk-factors considered in this study. The results indicated that the two new dental indicators are more sensitive to the influence of social and behavioural factors, such as those investigated here, than is the traditional DM FT index. A different set of weights (4, I, and I for sound, filled, and decayed) was suggested for the construction of the T-Health. 相似文献
94.
Schimpf PP Jamieson PM Khan MA Wagner RB 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》1988,15(1):49-51
After sustaining a free rupture of the intrapericardial ascending aorta secondary to blunt chest trauma, a 27-year-old man underwent successful aortic repair. To our knowledge, this is the first time a patient has ever survived this condition. Pericardial tamponade-together with rapid transport to the hospital and an aggressive surgical approach-was a key to the recovery of effective cardiac function and successful aortic repair. Although the patient succumbed to complications 74 days after surgery, this case illustrates the possibility of longterm survival after free rupture of the ascending aorta. The following report emphasizes the technical feasibility of controlling the perforated aortic root in such cases. 相似文献
95.
96.
97.
E Irschick K Miller M Berger D Sch?nitzer J Koller H Wagner W G?ttinger C Huber 《Transplantation》1989,48(6):986-990
Transplantation of unmatched allogeneic corneas into highly vascularized recipient eyes under the cover of short-term immunosuppression with cyclosporine enables permanent engraftment. The aim of this study was to further elucidate the mechanism(s) underlying this tolerant state. In eight "high-risk" cornea recipients the clone sizes of donor-specific and third-party reactive cytotoxic T cell precursors were assessed by limiting dilution analyses before and at three and six months after transplantation. Acquired allograft tolerance in these patients was not accompanied by clonal reduction of donor-specific CTL-p, whereas in the case of an irreversible rejection the donor-specific CTL pool size was significantly enlarged. This donor-specific CTL-p increase could already be seen two months before clinical manifestation. These patterns differed from that of tolerant renal transplant patients, in whom marked and donor-specific reduction of CTL-p was observed. During rejection identical patterns with increasing donor-specific CTL-p frequencies were seen in both groups of patients. We conclude that induction of tolerance by short-term CsA to unmatched cornea grafts is not caused by clonal reduction of the effector precursor cell pool. 相似文献
98.
Minor Iridoid and Phenol Glycosides of Picrorhiza kurrooa 总被引:3,自引:0,他引:3
From the roots of PICRORHIZA KURROOA a new iridoid glycoside, 6-feruloylcatalpol has been isolated, along with veronicoside and minecoside and two phenol glucosides, picein and androsin. 相似文献
99.
100.
Wagner Costalas J Itzen M Malick J Babb JS Bove B Godwin AK Daly MB 《American journal of medical genetics. Part C, Seminars in medical genetics》2003,(1):11-18
We describe results from a survey designed to assess patterns of communication within families shortly after an individual receives results of BRCA1 and BRCA2 mutation carrier status. Shortly after disclosure of BRCA1 and BRCA2 genetic test results, the proband was contacted by phone to administer the post disclosure survey. Questions asked included whether they had shared their results with their siblings or adult children, if there were difficulties in communicating the test results, and if there was any distress associated with the sharing of results. A total of 162 women who have received results from BRCA1 and BRCA2 genetic testing participated in the survey. The probands shared their results more often with their female than their male relatives (P < 0.001). Probands who had tested positive for a mutation in the BRCA1 or BRCA2 gene shared their results more often with their relatives than did probands who were not carriers (P = 0.002). Probands reported more often that their siblings rather than their adult children had difficulties understanding the results (P = 0.001). The probands who were carriers more often reported having difficulties explaining their results to their relatives (P < 0.001) and their relatives were upset on hearing the result more often than were the relatives of probands who were not carriers (P < 0.001). The probands who were carriers reported more often that they were upset explaining their results to their relatives than did the probands who were not carriers (P < 0.001). Individuals are disclosing their test results to their relatives. Probands who are BRCA1- or BRCA2-positive are more likely to experience difficulty and distress with the communication of their test results to family members. 相似文献