Acute Perforation in Spite of Implantation with an “Antiperforation” Defibrillator Lead

A 74‐year‐old male underwent implantation of implantable cardioverter defibrillator per multicenter automatic defibrillator trial two criteria. The new St. Jude Medical Riata STS Durata defibrillator lead (St. Jude Medical, Sylmar, CA, USA) was used. This lead has a slight curve at the right ventricle shock coil and a silicone tip designed to decrease tip pressure at the endocardium interface. We presented a case of acute perforation during implantation of this lead. The patient was treated with pericardiocentesis and recovered.     

p-Cresol: cause of ink-induced hair depigmentation in mice

p-Cresol has been identified as the active chemical in a laundry-ink responsible for the previously reported contact depigmentation of hair in agouti CBA/J mice. p-Cresol has been shown to induce depigmentation of both skin and hair in agouti as well as black mice. In the agouti mice there were bands and whorls, as well as plaques of white hair. However, the most striking finding was an occult hair depigmentation wherein the new hair shafts were white except for the tips. Such pigment-loss was not apparent on surface examination of the fur, becoming evident only on parting the hairs. All of these patterned hair pigment losses have been related to a unique sensitivity of the follicular melanocytes to the toxic effect of p-cresol during the earliest days of new hair formation, that is, during the initial anagen phase.     

Herpetic arthritis associated with disseminate herpes simplex in a wrestler

A case of widespread inoculation herpes simplex of the skin is reported in a wrestler. Five days after the skin lesions appeared, the right knee became markedly tender and swollen. Herpesvirus hoministype I was cultured from the joint exudate as well as from the skin lesions. The determinant of the monoarticular localization of the arthritis appeared to be a prior injury to the knee, rendering it a specific site for deposition of the blood-borne virus.