全文获取类型
收费全文 | 2518篇 |
免费 | 168篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 35篇 |
儿科学 | 167篇 |
妇产科学 | 47篇 |
基础医学 | 475篇 |
口腔科学 | 69篇 |
临床医学 | 230篇 |
内科学 | 511篇 |
皮肤病学 | 40篇 |
神经病学 | 194篇 |
特种医学 | 134篇 |
外科学 | 260篇 |
综合类 | 19篇 |
预防医学 | 164篇 |
眼科学 | 14篇 |
药学 | 190篇 |
中国医学 | 9篇 |
肿瘤学 | 141篇 |
出版年
2022年 | 20篇 |
2021年 | 36篇 |
2020年 | 32篇 |
2019年 | 47篇 |
2018年 | 61篇 |
2017年 | 45篇 |
2016年 | 38篇 |
2015年 | 49篇 |
2014年 | 66篇 |
2013年 | 85篇 |
2012年 | 131篇 |
2011年 | 133篇 |
2010年 | 75篇 |
2009年 | 66篇 |
2008年 | 94篇 |
2007年 | 101篇 |
2006年 | 105篇 |
2005年 | 94篇 |
2004年 | 80篇 |
2003年 | 59篇 |
2002年 | 79篇 |
2001年 | 85篇 |
2000年 | 78篇 |
1999年 | 63篇 |
1998年 | 53篇 |
1997年 | 37篇 |
1996年 | 32篇 |
1995年 | 31篇 |
1994年 | 35篇 |
1993年 | 22篇 |
1992年 | 43篇 |
1991年 | 42篇 |
1990年 | 32篇 |
1989年 | 37篇 |
1988年 | 40篇 |
1987年 | 22篇 |
1986年 | 29篇 |
1985年 | 33篇 |
1984年 | 18篇 |
1983年 | 28篇 |
1982年 | 25篇 |
1981年 | 17篇 |
1980年 | 18篇 |
1979年 | 27篇 |
1978年 | 23篇 |
1977年 | 16篇 |
1974年 | 19篇 |
1970年 | 16篇 |
1967年 | 19篇 |
1941年 | 17篇 |
排序方式: 共有2699条查询结果,搜索用时 0 毫秒
31.
32.
Donna L Forrest Donna E Hogge Thomas J Nevill Stephen H Nantel Michael J Barnett John D Shepherd Heather J Sutherland Cynthia L Toze Clayton A Smith Julye C Lavoie Kevin W Song Nicholas J Voss Randy D Gascoyne Joseph M Connors 《Journal of clinical oncology》2005,23(31):7994-8002
PURPOSE: To determine the incidence of second malignancies among patients with Hodgkin's lymphoma (HL) treated with autologous hematopoietic stem cell transplantation (AHSCT) compared with patients receiving conventional therapy alone and to identify potential risk factors for their occurrence. PATIENTS AND METHODS: We analyzed data on 1,732 consecutive patients with HL treated at the British Columbia Cancer Agency from 1976 to 2001, including 202 patients undergoing AHSCT. The median follow-up duration was 9.8 years for the whole cohort, 9.7 years for those patients treated with conventional therapy, and 7.8 years from AHSCT. RESULTS: The cumulative incidence of developing any second malignancy 15 years after therapy for HL was 9% (risk ratio = 3.5; P < .001); however, the incidence did not differ between those patients receiving conventional therapy alone compared with those undergoing AHSCT (10% and 8%, respectively; P = .48). In multivariate analysis, the only factor significantly associated with an increased risk of developing any second neoplasm or solid tumor was age > or = 35 years (P < .0001). An increased risk of therapy-induced acute myeloid leukemia and therapy-induced myelodysplastic syndrome was seen for patients aged > or = 35 years (P = .03) and stage III/IV (P = .04). CONCLUSION: Patients with HL are at increased risk of developing a second neoplasm. However, those patients undergoing AHSCT do not seem to be at greater risk compared with those patients receiving conventional therapy alone, at least during the first decade after therapy. 相似文献
33.
Adam R. Dyas Alyson D. Kelleher Crystal J. Erickson Jennifer A. Voss Ethan U. Cumbler Anne Lambert-Kerzner Annette S. Vizena Celisse Robinson-Chavez Brandi L. Kee Alison R. Barker Melissa S. Fuller Susan A. Miller Katherine O. McCabe Katharine M. Cook Simran K. Randhawa John D. Mitchell Robert A. Meguid 《Journal of thoracic disease》2022,14(8):2855
BackgroundImplementation of enhanced recovery after surgery (ERAS) pathways for patients undergoing anatomic lung resection have been reported at individual institutions. We hypothesized that an ERAS pathway can be successfully implemented across a large healthcare system including different types of hospital settings (academic, academic-affiliated, community).MethodsAn expert panel with representation from each hospital within a healthcare system was convened to establish a thoracic ERAS pathway for patients undergoing anatomic lung resection and to develop tools and analytics to ensure consistent application. The protocol was translated into an order set and pathway within the electronic health record (EHR). Iterative implementation was performed with recording of the processes involved. Barriers and facilitators to implementation were recorded.ResultsDevelopment and implementation of the protocol took 13 months from conception to rollout. Considerable change management was needed for consensus and incorporation into practice. Facilitators of change included peer accountability, incorporating ERAS care elements into the EHR, and conducting case reviews with timely feedback on protocol deviations. Barriers included institutional cultural differences, agreement in defining mindful deviation from the ERAS protocol, lack of access to specific coded data, and resource scarcity caused by the COVID-19 pandemic. Support from the hospital system’s executive leadership and institutional commitment to quality improvement helped overcome barriers and maintain momentum.ConclusionsDevelopment and implementation of a health-system wide thoracic ERAS protocol for anatomic lung resections across a six-hospital health system requires a multidisciplinary team approach. Barriers can be overcome though multidisciplinary team engagement and executive leadership support. 相似文献
34.
Maria Voss Kyhn Jens F. Kiilgaard Ana Garcia Lopez Erik Scherfig Jan U. Prause Morten La Cour 《Acta ophthalmologica. Supplement》2008,86(1):18-25
Purpose: The aim of the study was to determine the type and magnitude of detectable changes in pig multifocal electroretinography (mfERG) induced by the vitreoretinal surgical procedures necessary to gain access to the subretinal space. Methods: Twenty pigs underwent posterior segment surgery. Six animals had a vitrectomy (V), six had in addition a retinal bleb detachment (V + B); five had in addition a retinal diathermia on the bleb (V + B + D) and three received a retinotomy in the diathermized retinal area (V + B + D + R). mfERG evaluation was performed at baseline and 1 and 6 weeks postoperatively. Selected eyes were enucleated for histological evaluation. Results: The retinal detachments blebs all reattached spontaneously. All four surgical sequences resulted in slight, non‐significant changes in the mfERG peaks. A trend towards an amplitude reduction of the mfERG peaks N1, P1 and N2 were observed within the first postoperative week. After 6 weeks, all amplitudes had normalized. Of the implicit times only that of peak N1 (after retinal diathermia) was prolonged significantly at 1 week (P = 0.037). However, it returned to the preoperative level after 6 weeks. Histologically, the retinal detachment bleb was characterized by transient double layering of the retinal pigment epithelium (RPE) and loss photoreceptor outer segments. Conclusion: Access to the subretinal space in pigs can be gained without permanent detectable changes in the mfERG. A short‐term retinal detachment was found to cause only reversible electrophysiological and histological changes in the outer retina, which suggests that this procedure is tolerated well in the porcine retina. The size of the known destructive lesion (retinotomy) was too small to be detected, given the spatial resolution of the mfERG method applied. In the future, the presented protocol can be used to assess the functional outcome of surgery and transplantation in the subretinal space in pigs. 相似文献
35.
Christine M. Olney John E. Ferguson Greg Voss Eric Nickel Stuart Fairhurst Alexandra S. Bornstein Sara Kemmer Crystal Stien Kristin Scheel Charlotte Brenteson Ann Goding Mary Murphy Kruse Byron Eddy Gary Goldish Andrew H. Hansen 《The journal of spinal cord medicine》2023,46(1):146
Objective:To describe how using a supine arm cycle ergometer can safely reduce deconditioning experienced by patients with spinal cord injury or disorder (SCI/D) during their four to six weeks of complete bed rest after surgery to close a stage 4 pressure injury.Design:This pilot project used a newly designed arm cycle ergometer (known as the M-PACE) that extends over the bed, allowing a patient to lie completely supine while exercising.Setting:The M-PACE was designed and built at the Minneapolis Veterans Affairs Health Care System (MVAHCS) and pilot tested at the MVAHCS SCI/D Center.Participants:Patients with SCI/D, recovering from flap surgery and deemed appropriate to use the arm cycle ergometer were enrolled in the pilot study (n = 47).Outcome Measures:A pre–post six-minute arm test (6MAT), a proxy for conditioning, was conducted on a subset (n = 15) of participants before and after the supine cycling exercise training program. Participants’ rating of perceived exertion (RPE) scores were collected at cessation of each 6MAT. Participants gave feedback on their perception of using the M-PACE.Results/Conclusions:The 6MAT RPE was significantly reduced after training with the M-PACE while on bed rest (P = 0.003). Also, significantly more rotations were performed after completing the training program (P = 0.02). Further, study participants who accessed the M-PACE found using it helped offset the tedium of laying supine during flap surgery recovery. The differences in the 6MAT pre- to post measures indicate the M-PACE should be further studied for offsetting the normal deconditioning that occurs with extended bedrest. 相似文献
36.
Agustín Ciapponi Mabel Berrueta Jamile Ballivian Ariel Bardach Agustina Mazzoni Steven Anderson Fernando J. Argento Karin Bok Daniel Comand Erin Goucher Beate Kampmann Edward P. K. Parker Federico Rodriguez-Cairoli Victoria Santa Maria Andy Stergachis Gerald Voss Xu Xiong Sabra Zaraa Flor M. Munoz Ruth A. Karron Sami L. Gottlieb Pierre M. Buekens 《Medicine》2023,102(9)
37.
38.
W. Biedermann Robert E. Mark Voss 《Journal of cancer research and clinical oncology》1941,51(4-5):471-471
Ohne Zusammenfassung 相似文献
39.
40.