Neurophysiologic studies of the brain (principle trends and prospects)

Results of the analysis of 3675 papers dedicated to the neurophysiological brain research and published during 1983-84 are presented in the paper. Main directions of investigations and promising methods are elucidated. The sections of the brain neurophysiology which are either slightly developed or not developed at all are revealed.     

Total hip replacement for proximal femoral tumours: our midterm results

Data from 44 patients (23 males, 21 females) with a median age of 39 (range 13–80) years who underwent total hip arthroplasty for proximal femoral tumours (1994–2004) were analysed. The histological diagnoses included 14 metastases, six osteosarcomas, six chondrosarcomas, four Ewing’s sarcomas, four giant cell tumours, three malignant fibrous histiocytomas, two parosteal and two periosteal osteosarcomas, and one each primary neuroectodermal tumour, myeloid disease, and aneurysmal bone cyst. Twenty-one patients (48%) had pathological fractures. The cause of the pathological fracture was metastasis in 12 patients (57%). Twenty-eight patients (64%) had soft tissue invasion. Complications observed in 17 patients (37%) were local recurrence in two, postoperative haematoma in two, dislocation of prosthesis in five, deep infection in six, and one patient died of myocardial infarction in the early postoperative period. During our midterm survival analysis, functional results were excellent in 25% of patients, good in 57%, fair in 12%, and poor in 6%.

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Résumé Entre 1994 et 2004, nous avons récolté les données de 44 patients (23 hommes et 21 femmes), dont l’age moyen était de 39 ans (de 13 à 80), qui ont bénéficié d’une prothèse totale de hanche pour une tumeur de l’extrémité proximale du fémur 4. Le diagnostic étiologique a inclus, chez ces patients, 14 métastases, 6 ostéosarcomes, 6 chondrosarcomes, 4 sarcomes d’Ewing, 4 tumeurs à cellules géantes, 4 histiocytomes malins, 2 sarcomes paraosteal, 2 sarcomes périosters et une tumeur neuroectodermique, un myélome un kyste anévrismal. 21 patients (48%) présentaient une fracture pathologique. La fracture pathologique était une métastase chez 12 patients (soit 57%). Pour 28 patients (64%) avaient un envahissement des parties molles. Des complications ont été observées chez 17 patients (37%) avec 2 récidives locales de la tumeur, 2 hématomes post-opératoires, 5 luxations de prothèse, 6 infections profondes et un patient décédé d’infarctus du myocarde en post opératoire précoce. Le résultat fonctionnel a été noté excellent à moyen terme chez 25 patients, bon chez 57%, moyen pour 12% et mauvais pour 6% des patients.

     

Oxygen metabolism with low hematocrit levels in the course of guided hemodilution procedure in cardiosurgical patients

Influence of hemodilution on the oxygen metabolism in patients, operated, using the artificial blood circulation apparatus, was studied up. Factors, determining the oxygen delivery to tissues, was estimated, correlational links between the blood rheological properties and its oxygen--transporting function were established. Experience of application of apparatus Aeprex, promoting the oxygen delivery to tissue improvement and the need in donor's blood lowering, performing operations, using the artificial blood circulation apparatus.