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101.
Vergara C Tsai YJ Grant AV Rafaels N Gao L Hand T Stockton M Campbell M Mercado D Faruque M Dunston G Beaty TH Oliveira RR Ponte EV Cruz AA Carvalho E Araujo MI Watson H Schleimer RP Caraballo L Nickel RG Mathias RA Barnes KC 《American journal of respiratory and critical care medicine》2008,178(10):1017-1022
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Jo?o Alves de Araújo-Filho Arioldo Carvalho Vasconcelos-Jr Eduardo Martins de Sousa Colombina da Silveira Patrícia Tavares Pereira de Sousa Klaus Andrade Severo Ludmila Ferreira Vieira André Kipnis Ana Paula Junqueira-Kipnis 《The Brazilian journal of infectious diseases》2008,12(1):94-98
Multidrug-resistant tuberculosis (MDR-TB) is an emerging and worrisome health problem that threatens tuberculosis (TB) control worldwide. The clinical management of MDR-TB is a complex issue associated with the use of multiple drugs for a long period, usually accompanied by side effects and high costs. The objective of this work was to relate cases of MDR-TB occurring in Goiás, a central state of Brazil. We related five cases of MDR-TB, three women and two men. All were pulmonary cases. Three were in their second treatment and two in their first treatment. Surgical pulmonary resection was performed in one case. One death occurred. Lack of adherence, gastric intolerance to anti-TB drugs and poor clinical management were the main aspects related to the emergent resistance. A revision of the main clinical aspects of this disease was performed. 相似文献
107.
Clarice A. D. Caiuby Akbar Ali Vinicius T. Santana Francisco W. de S. Lucas Marilia S. Santos Arlene G. Corrêa Otaciro R. Nascimento Hao Jiang Mrcio W. Paixo 《RSC advances》2018,8(23):12879
The combination of visible-light and tris(trimethylsilyl)silane promoting intramolecular reductive cyclization protocol for the synthesis of functionalized indolines and 2,3-dihydrobenzofurans has been developed. The transformations occur in the absence of transition metal and additional photocatalyst. In addition, quantum yield (Φ) was determined and electron paramagnetic resonance spectroscopy was performed to better understand the reaction pathway.The combination of visible-light and tris(trimethylsilyl)silane promoting intramolecular reductive cyclization protocol for the synthesis of functionalized indolines and 2,3-dihydrobenzofurans has been developed. 相似文献
108.
Developing and Testing of a Software Prototype to Support Diagnostic Reasoning of Nursing Students 下载免费PDF全文
109.
Abbey Sawyer Vinicius Cavalheri Sue Jenkins Jamie Wood Nola Cecins Bhajan Singh Kylie Hill 《Sports medicine, arthroscopy, rehabilitation, therapy & technology》2018,10(1):19
Background
In people with cystic fibrosis (CF), higher exercise capacity is associated with better health-related quality of life (HRQoL), reduced risk of hospitalisation for a respiratory infection and survival. Therefore, optimisation of exercise capacity is an important treatment goal. The Australian and New Zealand clinical practice guidelines recommend that people with CF complete 30 to 60 min of moderate intensity aerobic exercise on most days of the week. This recommendation can be difficult to achieve by people with CF because of time constraints, and intolerable breathlessness and muscle fatigue during continuous exercise. In contrast, a low-volume, high intensity interval training (HIIT) program may be a more achievable and efficient training method to improve exercise capacity in people with CF.Methods
A randomised controlled trial will be undertaken. Forty people with CF (aged ≥15 years) will be randomly allocated, on a 1:1 ratio, to either the experimental or control group. Regardless of their group allocation, all participants will be asked to continue with their usual daily treatment for the study duration. Those in the experimental group will complete 8 weeks of thrice weekly HIIT on a cycle ergometer. Those in the control group will receive weekly contact with the investigators. The primary outcome of this study is exercise capacity. Secondary outcomes are HRQoL, exercise self-efficacy, feelings of anxiety, depression and enjoyment. These outcomes will be recorded at baseline (i.e. prior to randomisation) and following the 8-week intervention period. The study will also report other outcomes of the HIIT program (cardiovascular responses, symptom response, post-exercise muscle soreness and tolerance) and behaviour change techniques such as reinforcement, feedback and goal setting, used during the HIIT program.Discussion
This study will determine the effects of 8-weeks of supervised, low-volume HIIT, completed on a cycle ergometer on measures of exercise capacity, HRQoL, exercise self-efficacy, feelings of anxiety, depression and enjoyment. If effective, this type of training could be an attractive alternative to traditional continuous training because it may be more achievable and time efficient.Trial registration
Australian and New Zealand Clinical Trials Registry (ANZCTR):12617001271392 (04/09/2017).110.
Lucas Calais-Ferreira Vinicius C. Oliveira Jeffrey M. Craig Louisa B. Flander John L. Hopper Luci F. Teixeira-Salmela Paulo H. Ferreira 《Revista brasileira de fisioterapia (S?o Carlos (S?o Paulo, Brazil))》2018,22(3):184-189