全文获取类型
收费全文 | 736篇 |
免费 | 33篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 52篇 |
妇产科学 | 15篇 |
基础医学 | 96篇 |
口腔科学 | 7篇 |
临床医学 | 59篇 |
内科学 | 138篇 |
皮肤病学 | 15篇 |
神经病学 | 58篇 |
特种医学 | 29篇 |
外科学 | 94篇 |
综合类 | 6篇 |
预防医学 | 59篇 |
眼科学 | 8篇 |
药学 | 90篇 |
中国医学 | 3篇 |
肿瘤学 | 37篇 |
出版年
2023年 | 2篇 |
2022年 | 13篇 |
2021年 | 24篇 |
2020年 | 15篇 |
2019年 | 17篇 |
2018年 | 12篇 |
2017年 | 13篇 |
2016年 | 16篇 |
2015年 | 19篇 |
2014年 | 30篇 |
2013年 | 38篇 |
2012年 | 36篇 |
2011年 | 42篇 |
2010年 | 30篇 |
2009年 | 27篇 |
2008年 | 35篇 |
2007年 | 45篇 |
2006年 | 39篇 |
2005年 | 41篇 |
2004年 | 37篇 |
2003年 | 40篇 |
2002年 | 36篇 |
2001年 | 4篇 |
2000年 | 5篇 |
1999年 | 4篇 |
1998年 | 18篇 |
1997年 | 11篇 |
1996年 | 5篇 |
1995年 | 14篇 |
1994年 | 6篇 |
1993年 | 5篇 |
1992年 | 5篇 |
1991年 | 4篇 |
1990年 | 2篇 |
1989年 | 5篇 |
1988年 | 7篇 |
1987年 | 4篇 |
1986年 | 4篇 |
1985年 | 4篇 |
1984年 | 4篇 |
1980年 | 6篇 |
1979年 | 4篇 |
1978年 | 4篇 |
1977年 | 4篇 |
1975年 | 7篇 |
1974年 | 6篇 |
1973年 | 5篇 |
1972年 | 4篇 |
1971年 | 2篇 |
1967年 | 2篇 |
排序方式: 共有769条查询结果,搜索用时 15 毫秒
101.
Vida S. Sandoval Ashaki Jackson Erin Saleeby Lynne Smith Adam Schickedanz 《Academic pediatrics》2021,21(3):455-461
ObjectiveChildhood food insecurity endangers child development and health outcomes. Food insecurity will grow increasingly common in the economic wake of the coronavirus pandemic and prenatal care represents an early, clinical opportunity to identify families at risk. However, longitudinal relationships between clinically-identified prenatal food insecurity and prematurity, pediatric health care utilization, and postnatal social needs have not been described.MethodsWe examined longitudinal data from mother-child dyads who received prenatal and pediatric care and social needs screening at a large academically-affiliated safety net medical center between October 2018 and July 2019. Associations among household food insecurity and premature birth, pediatric inpatient and outpatient utilization, missed immunizations, and postnatal social needs were estimated using adjusted regression.ResultsAmong the 268 mothers, those who experienced prenatal household food insecurity had 3 times higher odds of having a child born prematurely (95% confidence interval [CI] 1.0–8.9, P = .05) and had children with higher inpatient hospitalizations (incidence rate ratio [IRR] 2.4, 95% CI 1.0–5.6, P = .04) and missed immunizations (IRR 3.4, 95% CI 1.1–10.3, P = .03) in the first 6 months of the child's life. These mothers also had higher odds of having any social needs in the pediatric setting (odds ratio 3.4; 95% CI 1.5–8.0, P = .004).ConclusionsPrenatal household food insecurity was linked to future adverse perinatal and pediatric outcomes in low-income mother-child dyads. Food insecurity identifies children at social and medical risk, providing an early clinical opportunity to intervene. 相似文献
102.
Srdjana Čulić Vida Čulić Visnja Armanda Dubravka Kuljiš Valdi Pešutić-Pisac Stipan Janković 《Pediatric hematology and oncology》2013,30(4):339-344
Intravenous therapy with the anti-CD20 antibody Rituximab has been recently approved for the treatment of CD20 positive non-Hodgkin's lymphoma (NHL) in adults but not in children. The authors present the benefits of its application for mediastinal NHL CD 20+ with a local extension into the lung of a 10-year-old-girl. Receiving the chemotherapy according to study NHL-BFM-95 for high-risk lymphoma the girl did not reach complete remission. Before the last chemotherapy block was started, a computed tomography scan of the thorax showed residue in the right lung. Twenty-five days after the last chemotherapy she received Rituximab at a dose of 375 mg/m 2 by intravenous infusion once a week for a total of four doses without the adverse reactions. Complete remission was achieved. The patient was high risk with lung involvement of lymphoma suggesting a pure prognosis. The results suggest that Rituximab may improve the outcome in high-risk patients and appeared to be safe and effective in children also. 相似文献
103.
Joseph C. Presti Jr Katsuto Shinohara Peter Bacchetti Vida Tigrani Vivek Bhargava 《Urology》1998,52(6):1079-1084
Objectives. To determine whether the positive fraction of systematic sextant biopsies contributes to the prediction of serologic relapse after radical prostatectomy.Methods. A retrospective review of patients who underwent transrectal ultrasound-guided systematic sextant biopsy and radical prostatectomy was performed. No patients received neoadjuvant or adjuvant therapy. The relationship between the positive fraction of systematic biopsies and risk of prostate-specific antigen recurrence was assessed with Kaplan-Meier and multivariate analyses.Results. Patients with three or fewer positive sextant biopsies were at a significantly lower risk of relapse after radical prostatectomy than patients with four or more positive biopsies. Tumor grade and systematic biopsy results were the most powerful predictors of serologic relapse.Conclusions. The positive fraction of systematic biopsies contributes to the prediction of risk of relapse after radical prostatectomy. 相似文献
104.
Estevam Barbosa de Las Casas André Fran?a de Almeida Carlos Alberto Cimini Junior Paulo de Tarso Vida Gomes Tulimar Pereira Machado Cornacchia Jorge Milton Elian Saffar 《Journal of applied oral science : revista FOB》2007,15(1):70-76
Oral forces applied to human teeth during biting and mastication are normally described in the literature only in terms of their axial components. The purpose of this study was to fully determine the spatial characteristics of the oral resultant force – its normal and tangential components - for a given individual. A load cell was especially manufactured to measure oral force and was temporarily implanted as a prosthetic device in the dental arch of a volunteer, replacing his missing upper first molar. The mastication and occlusion tests were carried out in such a way the cell should withstand the loads applied to the molar, and its state of strain was recorded by strain gauges attached to it. Based on the results of these tests and using balance equations, normal and tangential components of the resultant oral force were determined. For direct occlusion, without interposition any obstacle between cusps, a peak normal force of 135 N was recorded simultaneously to a tangential force of 44 N. For mastication of biscuits, a peak normal force of 133 N and a tangential force of 39 N were obtained. 相似文献
105.
Soulez G; Therasse E; Oliva VL; Pomp A; Busque S; Dagenais M; Deslandres E; Ghattas G; Gagner M 《Radiology》1997,204(3):780
106.
A Hajnal P Sándor G Jandó I Vida A Czurkó Z Karádi L Lénárd 《Brain research bulletin》1992,29(6):909-916
Kainic acid (KA), in various concentrations, was applied iontophoretically into the central nucleus of the amygdala. Microlesions with this cell specific neurotoxin caused body weight loss, hypo- or aphagia and hypo- or adipsia in a dose-dependent manner. EEG-examinations proved that even low doses of KA produced seizure activity; however, these epileptiform symptoms disappeared within the first 48 h after the operations. Thus, the lasting feeding disturbances produced by iontophoretic KA applications to the central nucleus of the amygdala (i.e., even these fine microlesions) were not related causally to the pathological EEG activity changes. Our findings, along with previous data, indicated that the body weight loss and feeding deficits were due to the KA-induced impairment of complex regulatory mechanisms. 相似文献
107.
108.
109.
George R. Honig R. George Mason Larry M. Tremaine Loyda N. Vida 《American journal of hematology》1978,5(4):335-340
Hemoglobin synthesis was studied in vitro in reticulocytes from a patient with the anti-Lepore variant Hb Lincoln Park. Incorporation of L-leucine-3H into the α and βδ chains of Hb Lincoln Park was substantially less than the incorporation into the corresponding globin chains of Hb A, with the rate of synthesis of the βδ chain being similar to that of the δ chain of Hb A2. Synthcis of the a and total non-α globin components was unbalanced, with a substantial excess of α chain synthesis. These findings help to explain the mild hemolytic disease present in individuals with this hemoglobin variant. 相似文献
110.
In patients with a bipolar disorder and well regulated lithium prophylaxis many psychological and social problems still remain. These can lead to non-compliance and relapse, which often increases the problems especially in the patient's direct environment. After group therapy, the self-confidence of 20 patients appeared to have improved compared with 14 control patients on the waiting-list for group therapy. The most important discovery for most of the patients was that their condition is not unique. They also gained the insight that they were potentially able to solve some of their problems themselves. 相似文献