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排序方式: 共有297条查询结果,搜索用时 15 毫秒
61.
A. Nilstad R. Bahr TE. Andersen 《Scandinavian journal of medicine & science in sports》2014,24(1):243-249
Methodological differences in epidemiologic studies have led to significant discrepancies in injury incidences reported. The aim of this study was to evaluate text messaging as a new method for injury registration in elite female football players and to compare this method with routine medical staff registration. Twelve teams comprising 228 players prospectively recorded injuries and exposure through one competitive football season. Players reported individually by answering three text messages once a week. A designated member of the medical staff conducted concurrent registrations of injuries and exposure. Injuries and exposure were compared between medical staff registrations from nine teams and their 159 affiliated players. During the football season, a total of 232 time‐loss injuries were recorded. Of these, 62% were captured through individual registration only, 10% by the medical staff only, and 28% were reported through both methods. The incidence of training injuries was 3.7 per 1000 player hours when calculated from individual registration vs 2.2 from medical staff registration [rate ratio (RR): 1.7, 1.2–2.4]. For match injuries, the corresponding incidences were 18.6 vs 5.4 (RR: 3.4, 2.4–4.9), respectively. There was moderate agreement for severity classifications in injury cases reported by both methods (kappa correlation coefficient: 0.48, confidence interval: 0.30–0.66). 相似文献
62.
Peter A. McCullough Melissa Zerka Esther Heimbach Maria Musialcyzk Thomas Spring Adam DeJong Syed S. Jafri Catherine Coleman Tamika Washington Shaheena Raheem Thomas Vanhecke Kerstyn C. Zalesin 《Clinical physiology and functional imaging》2010,30(5):369-374
Morbid obesity is believed to limit cardiovascular auscultation. We compared audiocardiography to senior attending physicians using conventional stethoscopes in 190 individuals with morbid obesity. Overall, there were 128 (67·4%) women and 62 (32·6%) men with mean ages of 44·9 ± 12·3 and 51·3 ± 10·8 , respectively (P = 0·001). The overall body mass index (BMI) was 47·3 ± 8·5 kg m?2. Of those with an S3 by audiocardiography (n = 7), one had a history of coronary artery disease (CAD), none had a history of heart failure, and one had a left ventricular ejection fraction (LVEF) <45%. The mean LVEF was 58·6 ± 9·9 versus 61·6 ± 5·3 for those with and without an S3 by audiocardiography (P = 0·16). By contrast, of those (n = 6) with an S3 by stethoscope, one had a history of CAD, two had histories of heart failure, and 3 had LVEF < 45%. The mean LVEF of those with and without S3 by stethoscope was 53·7 ± 2·3 and 61·6 ± 5·5%, respectively (P = 0·02). There were 40 (21·1%) patients with an S4 (S4 strength >5) identified by acoustic cardiography while there were 42 (22·1%) heard by the stethoscope and it was heard with both methods in nine patients (21·4% concordance). There were no significant correlations between BMI or peak oxygen consumption and S3 or S4 strength by audiocardiography. Acoustic cardiography performed with an electronic device was not helpful in assisting the cardiovascular examination of the morbidly obese. These data suggest the careful clinical exam with attention to traditional cardiac auscultation using a stethoscope in a quiet room should remain the gold standard. 相似文献
63.
Participation of older newly-diagnosed cancer patients in an observational prospective pilot study: an example of recruitment and retention 总被引:1,自引:0,他引:1
Martine TE Puts Johanne Monette Veronique Girre Christina Wolfson Michele Monette Gerald Batist Howard Bergman 《BMC cancer》2009,9(1):277-14
Background
There have been few prospective observational studies which recruited older newly-diagnosed cancer patients, and of these only some have reported information on the number needed to screen to recruit their study sample, and the number and reasons for refusal and drop-out. This paper reports on strategies to recruit older newly-diagnosed cancer patients prior to treatment into an observational prospective pilot study and to retain them during a six-month period. 相似文献64.
65.
Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinaemia 总被引:4,自引:0,他引:4
H. J. BLOM H. A. KLEINVELD† G. H. J. BOERS† P. N. M. DEMACKER† H. L. M. HAK-LEMMERS† M. T. W. B. TE POELE-POTHOFF J. M. F. TRIJBELS 《European journal of clinical investigation》1995,25(3):149-154
Abstract. The pathobiochemical mechanism of arteriosclerosis in hyperhomocysteinaemia has not yet been elucidated. In vitro studies have shown that the cytotoxic properties of homocysteine can be ascribed to its generation of reactive oxygen species. We studied lipid peroxidation, both in vivo and in vitro , in 10 homozygous cystathionine synthase-deficient (CSD) patients and in a control group of 10 healthy subjects of comparable age and sex. The susceptibility of low-density lipoprotein (LDL) from hyperhomo-cysteinaemic patients to oxidation was determined in vitro by continuously measuring the conjugated diene production induced by incubation with copper ions. Oxidation resistance (expressed as lag time), maximal oxidation rate, and extent of oxidation (expressed as total diene production) of LDL from CSD patients were not significantly different from those of LDL from controls. Furthermore, the time needed to reach maximal diene production, i.e. t(max), was similar for LDL from patients and controls. In addition, the vitamin E concentrations in LDL of CSD patients and controls were similar. The mean concentration (± SD) of plasma thiobarbituric acid reactive substances (TBARS), an indicator of in vivo lipid peroxidation, was 2.2 ± 0.7 μmol L-1 in CSD patients, a lower value than that measured in the matched controls (50± 2.0 μmol L-1 ). Investigation of in vivo and in vitro parameters of lipid peroxidation shows that the increased risk of arteriosclerosis in hyperhomocysteinaemia is unlikely to be due to increased lipid peroxidation. 相似文献
66.
Diaphragmatic rupture: CT findings in 11 patients 总被引:7,自引:0,他引:7
67.
68.
69.
We investigated whether cigarette smoking, measured by follicular fluid
concentrations of cotinine (a major metabolite of nicotine), affects the
maturity of oocytes from women undergoing in-vitro fertilization (IVF) and
embryo transfer. In 234 women, follicular fluid samples were assessed for
cotinine and their 2020 oocytes were assessed for maturity stage. Data on
individual proportions of oocytes which were mature (OM) and were
fertilized (OF) were analysed by regression in relation to age and
follicular fluid cotinine. OF gave an independent assessment of oocyte
maturity. Both age and follicular fluid cotinine entered the OM and OF
regressions and were significant. The age-adjusted regression coefficients
for log cotinine were positive; greater cotinine concentrations usually
accompanied greater OM and OF. The cotinine effect on OM was positive in
younger women, but it became negative (decreased OM with increasing
cotinine concentrations) in older women (> or = 40 years). We further
found in older women an average reduction of approximately 50% in the
number of mature oocytes; this reduced number was lower than the number of
embryos usually transferred. Smoking can reduce the number of mature
oocytes even further, therefore risking a negative IVF-embryo transfer
outcome. This may be the reason why the negative effects of smoking become
clinically detectable in older women.
相似文献
70.
Percutaneous abdominal biopsy: cost-identification analysis 总被引:1,自引:0,他引:1