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101.
Osamu Kainuma Yasushi Ito Tetsushi Taniguchi Takanori Shimizu Hisashi Nakada Yoko Date Tsuyoshi Hara 《Journal of gastroenterology》1996,31(3):460-464
We report a case of somatostatinoma of the ampulla of Vater associated with von Recklinghausen's disease in a 44-year-old
woman. On admission the patient was jaundiced, and percutaneous Cholangiodrainage was performed. Cholangiography revealed
stenosis of the common bile duct at the lower end Duodenoscopy showed a yellowish tumor of the ampulla of Vater, and the biopsy
specimens showed no malignant cells. Pylorus-preserving pancreaticoduodenectomy was performed. Histologically, the tumor was
composed of small round cells with a solid or trabecular pattern and with multiple psammoma bodies. Immunohistochemical examination
showed that the tumor cells stained for somatostatin. Genomic examination showed neither K-ras nor p53 gene mutations of the
resected specimen. 相似文献
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Chieko Sakano Makoto Kuroda Tsuyoshi Sekizuka Taisei Ishioka Yukio Morita Akihide Ryo Hiroyuki Tsukagoshi Yuko Kawai Nobuko Inoue Hayato Takada Yumiko Ogaswara Atsuyoshi Nishina Masa-aki Shimoda Kunihisa Kozawa Kazunori Oishi Hirokazu Kimura 《Journal of clinical microbiology》2013,51(1):328-330
Whole-genome sequencing of non-H2S-producing Salmonella enterica serovar Typhimurium and S. enterica serovar Infantis isolates from poultry meat revealed a nonsense mutation in the phsA thiosulfate reductase gene and carriage of a CMY-2 β-lactamase. The lack of production of H2S might lead to the incorrect identification of S. enterica isolates carrying antimicrobial resistance genes. 相似文献
103.
Mayu Harada Takeshi Terao Koji Hatano Kentaro Kohno Yasuo Araki Yoshinori Mizokami Kensuke Kodama Nobuhiko Hoaki Miyano Arasaki Tsuyoshi Shimomura Minoru Fujiki Takanori Kochiyama 《Journal of affective disorders》2013
Background
Hyperthymic temperament has been generally accepted as one of premorbid temperament of bipolar disorders. Although several studies indicate that subjects with hyperthymic temperament receive more illuminance, our recent study suggests that the threshold of brightness and darkness judgment is not different between more and less hyperthymic subjects, and that hyperthymic temperament may be associated with left inferior orbitofrontal cortex, which has been reported to be associated with bipolar disorder. Therefore, at the next stage, it can be hypothesized that hyperthymic subjects may prefer brightness (i.e., heliotropism) and thereby seek illuminance, and that percent signal changes of left inferior orbitofrontal cortex during the preference task may be associated with hyperthymic temperament scores.Methods
We compared brightness preference and un-preference between more and less hyperthymic subjects, and investigated percent signal changes of left inferior orbitofrontal cortex during brightness preference judgment, brightness un-preference judgment, and control task by using functional Magnetic Resonance Imaging (fMRI).Results
There were significant differences in brightness preference judgment and un-preference judgment, showing that more hyperthymic subjects preferred brighter illuminace levels and un-preferred darker illuminance levels than less hyperthymic subjects. Moreover, fMRI signal changes of left inferior orbitofrontal cortex was significantly and negatively associated with hyperthymic temperament scores.Limitations
It is unknown why left but not right inferior orbitofrontal cortex was associated with hyperthymic temperament scores.Conclusions
The present findings suggest that more hyperthymic subjects may prefer brightness and un-prefer darkness than less hyperthymic subjects (i.e., heliotropism), and reconfirm that hyperthymic temperament may be associated with left inferior orbitofrontal cortex, which have been reported to be associated with bipolar disorders. 相似文献104.
Mime Kobayashi Ryosuke Honda Tsuyoshi Ando Masao Tanihara 《Journal of biomaterials science. Polymer edition》2013,24(13):1161-1171
AbstractWe have developed biocompatible scaffolds that enable cell fate control with visible light. The scaffolds are based on synthetic collagen-like polypeptide, poly(prolyl-hydroxyprolyl-glycyl) {poly(Pro-Hyp-Gly)} which has been used for cosmetics and other healthcare applications. Bioactive peptides were conjugated to the scaffolds via photoactivation reaction utilizing 488?nm visible light. In addition, the use of a photocleavable crosslinker enables dissociation of chemical moieties by 405?nm laser irradiation. The synthesis scheme enables optical control to attach and detach functional peptides in pre-patterned shapes. Using bone forming peptide (BFP), we demonstrate that calcium deposition by rat bone stromal cells can be directed on the scaffold. Using other signaling molecules and three-dimensional scaffolds, controlled differentiation of stem cells can be achieved by spatio-temporally specific irradiation of confocal microscope laser. 相似文献
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Tanaka Kazunari Katanuma Akio Hayashi Tsuyoshi Kin Toshifumi Takahashi Kuniyuki 《Journal of Medical Ultrasonics》2021,48(2):187-198
Journal of Medical Ultrasonics - Endoscopic ultrasonography (EUS) has excellent spatial resolution and allows more detailed examination than abdominal ultrasonography (US) in terms of qualitative... 相似文献
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